Clozapine

5-hydroxytryptamine receptor 1A ; Homo sapiens







23 Article(s)
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1 33805130 Development of a New Polymeric Nanocarrier Dedicated to Controlled Clozapine Delivery at the Dopamine D2-Serotonin 5-HT1A Heteromers. 2021 Mar 24 1
2 31636356 A functional HTR1A polymorphism, rs6295, predicts short-term response to lurasidone: confirmation with meta-analysis of other antipsychotic drugs. 2020 Apr 1
3 26876117 Dopamine D2 and serotonin 5-HT1A receptor interaction in the context of the effects of antipsychotics - in vitro studies. 2016 May 2
4 25560469 COMT Val158Met and 5-HT1A-R -1019 C/G polymorphisms: effects on the negative symptom response to clozapine. 2015 Jan 2
5 24423786 Improving cognition in schizophrenia with antipsychotics that elicit neurogenesis through 5-HT(1A) receptor activation. 2014 Apr 1
6 24429224 Clozapine effects on adenylyl cyclase activity and serotonin type 1A receptors in human brain post-mortem. 2014 Apr 4
7 22044428 Clozapine functions through the prefrontal cortex serotonin 1A receptor to heighten neuronal activity via calmodulin kinase II-NMDA receptor interactions. 2012 Feb 3
8 22283753 Serotonin receptors as targets for drugs useful to treat psychosis and cognitive impairment in schizophrenia. 2012 Jun 1
9 22419526 Increased levels of 5-HT1A receptor binding in ventral visual pathways in Parkinson's disease. 2012 May 1
10 19149529 Atypical neuroleptic malignant syndrome or serotonin toxicity associated with atypical antipsychotics? 2009 Jan 1
11 18707769 Does stimulation of 5-HT(1A) receptors improve cognition in schizophrenia? 2008 Dec 16 1
12 16697427 QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine. 2006 Aug 1
13 16918396 Pharmacological profile of antipsychotics at monoamine receptors: atypicality beyond 5-HT2A receptor blockade. 2006 Aug 2
14 15358978 A positron emission tomography study of the 5-HT1A receptor in schizophrenia and during clozapine treatment. 2004 Sep 2
15 12589516 Occupancy of 5-HT1A receptors by clozapine in the primate brain: a PET study. 2003 Mar 3
16 12923612 Comparison of hippocampal G protein activation by 5-HT(1A) receptor agonists and the atypical antipsychotics clozapine and S16924. 2003 Sep 2
17 11997696 Increasing D2 affinity results in the loss of clozapine's atypical antipsychotic action. 2002 May 7 1
18 11163544 Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia. 2001 Jan 15 2
19 10087034 S-16924, a novel, potential antipsychotic with marked serotonin1A agonist properties. IV. A drug discrimination comparison with clozapine. 1999 Apr 1
20 9732398 S 16924 ((R)-2-[1-[2-(2,3-dihydro-benzo[1,4] dioxin-5-Yloxy)-ethyl]-pyrrolidin-3yl]-1-(4-fluoro-phenyl)-ethanone), a novel, potential antipsychotic with marked serotonin (5-HT)1A agonist properties: I. Receptorial and neurochemical profile in comparison with clozapine and haloperidol. 1998 Sep 1
21 9369342 5-HT1A receptor agonist properties of the antipsychotic, nemonapride: comparison with bromerguride and clozapine. 1997 Sep 10 1
22 8684591 Clozapine is a partial agonist at cloned, human serotonin 5-HT1A receptors. 1996 Jan 2
23 1426017 Clozapine has sub-micromolar affinity for 5-HT1A receptors in human brain tissue. 1992 Oct 20 2