| 1 |
35042744 | Hypoxia-Inducible Factors in Cancer. | 2022 Jan 15 |
1 |
| 2 |
35205407 | The Role of VHL in the Development of von Hippel-Lindau Disease and Erythrocytosis. | 2022 Feb 17 |
1 |
| 3 |
35247316 | The evolutionarily conserved arginyltransferase 1 mediates a pVHL-independent oxygen-sensing pathway in mammalian cells. | 2022 Mar 14 |
3 |
| 4 |
35323939 | Elongin C (ELOC/TCEB1) associated von Hippel-Lindau disease. | 2022 Mar 21 |
2 |
| 5 |
33799686 | Prolyl Hydroxylase 3 Knockdown Accelerates VHL-Mutant Kidney Cancer Growth In Vivo. | 2021 Mar 11 |
2 |
| 6 |
34209205 | Molecular Insights into the Oxygen-Sensing Pathway and Erythropoietin Expression Regulation in Erythropoiesis. | 2021 Jun 30 |
1 |
| 7 |
34376376 | Von Hippel-Lindau tumor suppressor pathways & corresponding therapeutics in kidney cancer. | 2021 Jul 20 |
2 |
| 8 |
34431623 | Amyloidogenic Properties of Peptides Derived from the VHL Tumor Suppressor Protein. | 2021 Dec 6 |
1 |
| 9 |
34537235 | HIF-1α Hydroxyprolines Modulate Oxygen-Dependent Protein Stability Via Single VHL Interface With Comparable Effect on Ubiquitination Rate. | 2021 Nov 5 |
2 |
| 10 |
32255719 | The Genomics and Genetics of Oxygen Homeostasis. | 2020 Aug 31 |
1 |
| 11 |
32339495 | Understanding the Oxygen-Sensing Pathway and Its Therapeutic Implications in Diseases. | 2020 Aug |
2 |
| 12 |
32943729 | Androgen receptor modulates metastatic routes of VHL wild-type clear cell renal cell carcinoma in an oxygen-dependent manner. | 2020 Oct |
4 |
| 13 |
33020645 | Targeting the HIF2-VEGF axis in renal cell carcinoma. | 2020 Oct |
3 |
| 14 |
33142830 | Hypoxia and Oxygen-Sensing Signaling in Gene Regulation and Cancer Progression. | 2020 Oct 31 |
2 |
| 15 |
30194449 | Arginine refolds, stabilizes, and restores function of mutant pVHL proteins in animal model of the VHL cancer syndrome. | 2019 Feb |
1 |
| 16 |
31337753 | Evolution of metazoan oxygen-sensing involved a conserved divergence of VHL affinity for HIF1α and HIF2α. | 2019 Jul 23 |
1 |
| 17 |
31375625 | EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance. | 2019 Aug 20 |
4 |
| 18 |
28925400 | The HIF and other quandaries in VHL disease. | 2018 Jan 11 |
1 |
| 19 |
29121446 | VBP1 represses cancer metastasis by enhancing HIF-1α degradation induced by pVHL. | 2018 Jan |
1 |
| 20 |
29373688 | Compromised JMJD6 Histone Demethylase Activity Affects VHL Gene Repression in Preeclampsia. | 2018 Apr 1 |
1 |
| 21 |
29741264 | Genetic basis of congenital erythrocytosis. | 2018 May |
1 |
| 22 |
29938199 | Hypoxia-Inducible Factor 2-Dependent Pathways Driving Von Hippel-Lindau-Deficient Renal Cancer. | 2018 |
1 |
| 23 |
30105105 | Bilateral Pheochromocytomas in a Patient with Y175C Von Hippel-Lindau Mutation. | 2018 |
1 |
| 24 |
30619851 | Possible Role of PHD Inhibitors as Hypoxia-Mimicking Agents in the Maintenance of Neural Stem Cells' Self-Renewal Properties. | 2018 |
1 |
| 25 |
28400504 | Cardiopulmonary phenotype associated with human PHD2 mutation. | 2017 Apr |
2 |
| 26 |
29032393 | Acute effects of repeated cycling sprints in hypoxia induced by voluntary hypoventilation. | 2017 Dec |
2 |
| 27 |
29158891 | Overexpression of hypoxia-inducible factor and metabolic pathways: possible targets of cancer. | 2017 |
1 |
| 28 |
26620126 | (1)H NMR metabolomics analysis of renal cell carcinoma cells: Effect of VHL inactivation on metabolism. | 2016 May 15 |
1 |
| 29 |
26846855 | Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling. | 2016 Apr 1 |
1 |
| 30 |
27693634 | pVHL mediates K63-linked ubiquitination of IKKβ, leading to IKKβ inactivation. | 2016 Dec 1 |
1 |
| 31 |
27932568 | Targeting HIF2 in Clear Cell Renal Cell Carcinoma. | 2016 |
1 |
| 32 |
25500545 | RSUME inhibits VHL and regulates its tumor suppressor function. | 2015 Sep 10 |
1 |
| 33 |
25533676 | VHL, the story of a tumour suppressor gene. | 2015 Jan |
1 |
| 34 |
25936780 | NDRG3-mediated lactate signaling in hypoxia. | 2015 Jun |
1 |
| 35 |
26037477 | Jumonji Domain Containing Protein 6: A Novel Oxygen Sensor in the Human Placenta. | 2015 Aug |
1 |
| 36 |
26296657 | pVHL interacts with Ceramide kinase like (CERKL) protein and ubiquitinates it for oxygen dependent proteasomal degradation. | 2015 Nov |
2 |
| 37 |
26574473 | Quantifying the Binding Interaction between the Hypoxia-Inducible Transcription Factor and the von Hippel-Lindau Suppressor. | 2015 Aug 11 |
1 |
| 38 |
26611735 | Phospholipase D2 promotes degradation of hypoxia-inducible factor-1α independent of lipase activity. | 2015 Nov 27 |
2 |
| 39 |
25298778 | Multiple Components of the VHL Tumor Suppressor Complex Are Frequently Affected by DNA Copy Number Loss in Pheochromocytoma. | 2014 |
1 |
| 40 |
25361009 | Phospholipase D1 protein coordinates dynamic assembly of HIF-1α-PHD-VHL to regulate HIF-1α stability. | 2014 Dec 15 |
1 |
| 41 |
25440060 | Hif-2α promotes degradation of mammalian peroxisomes by selective autophagy. | 2014 Nov 4 |
1 |
| 42 |
23011899 | Simulation of the mutation F76del on the von Hippel-Lindau tumor suppressor protein: mechanism of the disease and implications for drug development. | 2013 Feb |
2 |
| 43 |
24386511 | Interaction of HIF-1α and Notch3 Is Required for the Expression of Carbonic Anhydrase 9 in Breast Carcinoma Cells. | 2013 Nov |
1 |
| 44 |
22086907 | Association of the von Hippel-Lindau protein with AUF1 and posttranscriptional regulation of VEGFA mRNA. | 2012 Jan |
1 |
| 45 |
22113277 | Transcriptional regulation of genes via hypoxia-inducible factor. | 2012 |
1 |
| 46 |
22207131 | Dynamic regulation of Th17 differentiation by oxygen concentrations. | 2012 Mar |
1 |
| 47 |
22406000 | Renal cancer: oxygen meets metabolism. | 2012 May 15 |
1 |
| 48 |
22562152 | The updated biology of hypoxia-inducible factor. | 2012 May 30 |
2 |
| 49 |
20802534 | Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor. | 2011 Jan 6 |
1 |
| 50 |
21069338 | Antitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase. | 2011 Aug |
1 |