trichostatin A

histone deacetylase 1 ; Homo sapiens







71 Article(s)
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1 33576217 Effect of Valproic Acid on the Class I Histone Deacetylase 1, 2 and 3, Tumor Suppressor Genes p21WAF1/CIP1 and p53, and Intrinsic Mitochondrial Apoptotic Pathway, Pro- (Bax, Bak, and Bim) and anti- (Bcl-2, Bcl-xL, and Mcl-1) Apoptotic Genes Expression, Cell Viability, and Apoptosis Induction in Hepatocellular Carcinoma HepG2 Cell Line. 2021 Feb 1 2
2 33649777 HDAC inhibitors suppress the proliferation, migration and invasiveness of human head and neck squamous cell carcinoma cells via p63‑mediated tight junction molecules and p21‑mediated growth arrest. 2021 Apr 2
3 33818027 Trichostatin A sensitizes hepatoma cells to Taxol more than 5-Aza-dC and dexamethasone. 2021 Apr 5 1
4 34773731 Trichostatin A sensitizes hepatoma cells to Taxol more than 5-Aza-dC and dexamethasone. 2021 Apr 5 1
5 31950542 HDAC1 and HDAC2 regulate anti-inflammatory effects of anesthetic isoflurane in human monocytes. 2020 Apr 1
6 33194023 ΔNp63α promotes the expression and nuclear translocation of PTEN, leading to cisplatin resistance in oral cancer cells. 2020 1
7 30518985 Histone deacetylase inhibition disturbs the balance between ACE and chymase expression in endothelial cells: a potential mechanism of chymase activation in preeclampsia. 2019 Feb 1
8 31256937 C/EBPε ΔRS derived from a neutrophil-specific granule deficiency patient interacts with HDAC1 and its dysfunction is restored by trichostatin A. 2019 Aug 13 2
9 31516890 Effect of 5-Aza-2'-Deoxycytidine in Comparison to Valproic Acid and Trichostatin A on Histone Deacetylase 1, DNA Methyltransferase 1, and CIP/KIP Family (p21, p27, and p57) Genes Expression, Cell Growth Inhibition, and Apoptosis Induction in Colon Cancer SW480 Cell Line. 2019 1
10 28884479 Transcriptional repression of Aurora-A gene by wild-type p53 through directly binding to its promoter with histone deacetylase 1 and mSin3a. 2018 Jan 1 4
11 29374219 Depletion of HDAC1, 7 and 8 by Histone Deacetylase Inhibition Confers Elimination of Pancreatic Cancer Stem Cells in Combination with Gemcitabine. 2018 Jan 26 2
12 30090184 Trichostatin A Restores Expression of Adherens and Tight Junction Proteins during Transforming Growth Factor β-Mediated Epithelial-to-Mesenchymal Transition. 2018 Jul-Sep 1
13 28012453 The effect of histone deacetylase inhibition on the expression of P-glycoprotein in human placental trophoblast cell lines. 2017 Jan 1
14 28524836 Effect of Histone Deacetylase Inhibition on the Expression of Multidrug Resistance-associated Protein 2 in a Human Placental Trophoblast Cell Line. 2017 Jun 5 1
15 25409339 Treatment of buffalo (Bubalus bubalis) donor cells with trichostatin A and 5-aza-2'-deoxycytidine alters their growth characteristics, gene expression and epigenetic status and improves the in vitro developmental competence, quality and epigenetic status of cloned embryos. 2016 Apr 1
16 27220438 [Effect of hydroquinone on the histone deacetylase in human bone marrow mononuclear cells]. 2016 Mar 20 2
17 27353169 MiR-548an, Transcriptionally Downregulated by HIF1α/HDAC1, Suppresses Tumorigenesis of Pancreatic Cancer by Targeting Vimentin Expression. 2016 Sep 1
18 25434997 Trichostatin A, a histone deacetylase inhibitor, reverses epithelial-mesenchymal transition in colorectal cancer SW480 and prostate cancer PC3 cells. 2015 Jan 2 1
19 25036040 Integrating genomics and proteomics data to predict drug effects using binary linear programming. 2014 1
20 25057056 [Inhibitory effect of trichostatin A on HepG2 cell proliferation and the mechanisms]. 2014 Jun 2
21 22355002 Methylation characteristics and developmental potential of Guangxi Bama minipig (Sus scrofa domestica) cloned embryos from donor cells treated with trichostatin A and 5-aza-2'-deoxycytidine. 2013 May 1
22 23709006 Inhibition of DNA methyltransferases, histone deacetylases and lysine-specific demethylase-1 suppresses the tumorigenicity of the ovarian cancer ascites cell line SKOV3. 2013 Aug 1
23 24007823 Treatment of donor cells with trichostatin A improves in vitro development and reprogramming of buffalo (Bubalus bubalis) nucleus transfer embryos. 2013 Nov 1
24 21957129 Opposed regulation of type I IFN-induced STAT3 and ISGF3 transcriptional activities by histone deacetylases (HDACS) 1 and 2. 2012 Jan 1
25 21983014 Dimethylcelecoxib induces an inhibitory complex consisting of HDAC1/NF-κB(p65)RelA leading to transcriptional downregulation of mPGES-1 and EGR1. 2012 Feb 2
26 22156375 HDAC1 regulates pluripotency and lineage specific transcriptional networks in embryonic and trophoblast stem cells. 2012 Apr 1
27 22158273 Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide. 2012 Jan 3 1
28 22270849 P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells. 2012 May 1
29 21636851 Epigenetic regulation of phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 gene expression in prostate cancer cells. 2011 Jul 22 1
30 25961258 Liposomal trichostatin A: therapeutic potential in hormone-dependent and -independent breast cancer xenograft models. 2011 May 1 1
31 19277896 Mode of action of the retrogene product SNAI1P, a SNAIL homolog, in human breast cancer cells. 2010 Mar 1
32 19699029 Troglitazone inhibits histone deacetylase activity in breast cancer cells. 2010 Feb 28 1
33 20946668 Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells. 2010 Oct 14 1
34 19417144 Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis. 2009 May 1
35 18322101 Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition. 2008 Mar 5 1
36 18596044 Unlocking repression of the human luteinizing hormone receptor gene by trichostatin A-induced cell-specific phosphatase release. 2008 Aug 29 1
37 18822204 [Effects of trichostatin A on the interaction between HBx and histone deacetylase protein 1]. 2008 Sep 6
38 17226765 Dual transcriptional control of claudin-11 via an overlapping GATA/NF-Y motif: positive regulation through the interaction of GATA, NF-YA, and CREB and negative regulation through the interaction of Smad, HDAC1, and mSin3A. 2007 Jun 1
39 17625602 Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells. 2007 Oct 1
40 18059533 Competitive inhibition of histone deacetylase activity by trichostatin A and butyrate. 2007 Dec 1
41 18253084 Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation? 2007 Oct 1
42 16528103 Histone deacetylase 3 binds to and regulates the GCMa transcription factor. 2006 2
43 15716589 Histone deacetylase 1: a target of 9-hydroxystearic acid in the inhibition of cell growth in human colon cancer. 2005 Aug 2
44 15722551 Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthase. 2005 Apr 22 1
45 16121030 Histone deacetylase-1 represses transcription by interacting with zinc-fingers and interfering with the DNA binding activity of Sp1. 2005 2
46 16150558 The Krüppel-like zinc-finger protein ZNF224 represses aldolase A gene transcription by interacting with the KAP-1 co-repressor protein. 2005 Oct 10 1
47 16186112 Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes. 2005 Nov 18 1
48 16197452 Transcription repression activity is associated with the type I isoform of the MMSET gene involved in t(4;14) in multiple myeloma. 2005 Oct 1
49 15051827 Krüppel-like factor 4 is transactivated by butyrate in colon cancer cells. 2004 Apr 3
50 12482978 Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain. 2003 Jan 2