Dexmedetomidine

interleukin 6 ; Mus musculus







23 Article(s)
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1 35412062 Dexmedetomidine attenuates hippocampal neuroinflammation in postoperative neurocognitive disorders by inhibiting microRNA-329-3p and activating the CREB1/IL1RA axis. 2022 Jul 1
2 35538293 MiR-665 Participates in the Protective Effect of Dexmedetomidine in Ischemic Stroke by ROCK2/NF-κB Axis. 2022 Jul 1
3 33179100 Dexmedetomidine attenuates sevoflurane‑induced neurocognitive impairment through α2‑adrenoceptors. 2021 Jan 1
4 33220278 Dexmedetomidine inhibits LPS-induced inflammatory responses through peroxisome proliferator-activated receptor gamma (PPARγ) activation following binding to α2 adrenoceptors. 2021 Feb 5 2
5 33821300 Dexmedetomidine ameliorates lipopolysaccharide-induced acute lung injury by inhibiting the PI3K/Akt/FoxO1 signaling pathway. 2021 Jun 1
6 34278508 Dexmedetomidine alleviates early brain injury following traumatic brain injury by inhibiting autophagy and neuroinflammation through the ROS/Nrf2 signaling pathway. 2021 Sep 2
7 34421084 Dexmedetomidine relieved neuropathic pain and inflammation response induced by CCI through HMGB1/TLR4/NF-κB signal pathway. 2021 Aug 20 1
8 31954762 Dexmedetomidine attenuates ethanol-induced inhibition of hippocampal neurogenesis in neonatal mice. 2020 Mar 1 1
9 32065090 Dexmedetomidine Pretreatment Improves Lipopolysaccharide-induced Iron Homeostasis Disorder in Aged Mice. 2020 1
10 32145512 Dexmedetomidine preconditioning alleviated murine liver ischemia and reperfusion injury by promoting macrophage M2 activation via PPARγ/STAT3 signaling. 2020 Mar 4 1
11 32632241 Dexmedetomidine promotes the progression of hepatocellular carcinoma through hepatic stellate cell activation. 2020 Jul 1
12 30964190 Therapeutic effect of dexmedetomidine on intracerebral hemorrhage via regulating NLRP3. 2019 Mar 1
13 31572546 Dexmedetomidine attenuates oxidative/nitrative stress in lung tissues of septic mice partly via activating heme oxygenase-1. 2019 Oct 1
14 29269298 Dexmedetomidine attenuates pancreatic injury and inflammatory response in mice with pancreatitis by possible reduction of NLRP3 activation and up-regulation of NET expression. 2018 Jan 22 1
15 29545877 3-Methyladenine and dexmedetomidine reverse lipopolysaccharide-induced acute lung injury through the inhibition of inflammation and autophagy. 2018 Apr 1
16 30071186 The effect of dexmedetomidine on inflammatory inhibition and microglial polarization in BV-2 cells. 2018 Oct 1
17 28224201 Dexmedetomidine protects against cisplatin-induced acute kidney injury in mice through regulating apoptosis and inflammation. 2017 May 1
18 28298895 Two Phase Modulation of [Formula: see text] Entry and Cl-/[Formula: see text] Exchanger in Submandibular Glands Cells by Dexmedetomidine. 2017 1
19 28555511 Mitigation of inflammation using the intravenous anesthetic dexmedetomidine in the mouse air pouch model. 2017 Aug 1
20 28784305 Dexmedetomidine (DEX) protects against hepatic ischemia/reperfusion (I/R) injury by suppressing inflammation and oxidative stress in NLRC5 deficient mice. 2017 Nov 18 1
21 26702389 The role of spleen in the treatment of experimental lipopolysaccharide-induced sepsis with dexmedetomidine. 2015 1
22 24803295 Dexmedetomidine controls systemic cytokine levels through the cholinergic anti-inflammatory pathway. 2014 Oct 1
23 19181340 Effects of dexmedetomidine on regulating endotoxin-induced up-regulation of inflammatory molecules in murine macrophages. 2009 Jun 15 1