Metformin

interleukin 6 ; Mus musculus







36 Article(s)
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1 35145895 Aqueous and alcoholic extracts of Artemisia annua L. improved insulin resistance via decreasing TNF-alpha, IL-6 and free fatty acids in high-fat diet/streptozotocin-induced diabetic mice. 2022 Jan-Feb 2
2 33947424 Metformin ameliorates scleroderma via inhibiting Th17 cells and reducing mTOR-STAT3 signaling in skin fibroblasts. 2021 May 4 1
3 31102492 Metformin shows anti-inflammatory effects in murine macrophages through Dicer/microribonucleic acid-34a-5p and microribonucleic acid-125b-5p. 2020 Jan 1
4 31902918 Metformin Suppresses LPS-Induced Inflammatory Responses in Macrophage and Ameliorates Allergic Contact Dermatitis in Mice via Autophagy. 2020 1
5 31977586 Effects of metformin on lipopolysaccharide-induced depressive-like behavior in mice and its mechanisms. 2020 Mar 4 1
6 32377293 Metformin Ameliorates Aβ Pathology by Insulin-Degrading Enzyme in a Transgenic Mouse Model of Alzheimer's Disease. 2020 1
7 32443237 Identification and validation of metformin protects against PM2.5-induced macrophages cytotoxicity by targeting toll like receptor pathway. 2020 Jul 1
8 32471963 The concentration-dependent pro-fibrotic effect of metformin on LPS and high glucose induced fibroblast NIH 3T3 and Macrophage RAW 264.7 Cell co-culture. 2020 May 2
9 30896853 Renal dysfunction in a mouse model of GDM is prevented by metformin through MAPKs. 2019 May 1
10 30935688 Metformin alleviates inflammatory response in non-alcoholic steatohepatitis by restraining signal transducer and activator of transcription 3-mediated autophagy inhibition in vitro and in vivo. 2019 May 21 1
11 31319131 AMPK as a potential pharmacological target for alleviating LPS-induced acute lung injury partly via NLRC4 inflammasome pathway inhibition. 2019 Oct 1 1
12 28935544 Metformin improves obesity-associated inflammation by altering macrophages polarization. 2018 Feb 5 2
13 29157127 Modulation of the gut microbiota by metformin improves metabolic profiles in aged obese mice. 2018 Mar 4 1
14 29545331 Metformin Suppresses Tumor Progression by Inactivating Stromal Fibroblasts in Ovarian Cancer. 2018 Jun 1
15 29554661 Alkannin Inhibited Hepatic Inflammation in Diabetic Db/Db Mice. 2018 1
16 29655055 Geniposide improves hepatic inflammation in diabetic db/db mice. 2018 Jun 1
17 29659176 Nrf2 attenuates inflammatory response in COPD/emphysema: Crosstalk with Wnt3a/β-catenin and AMPK pathways. 2018 Jul 2
18 29859833 Metformin alleviated endotoxemia-induced acute lung injury via restoring AMPK-dependent suppression of mTOR. 2018 Aug 1 2
19 30230981 Metformin Inhibits Chemokine Expression Through the AMPK/NF-κB Signaling Pathway. 2018 Sep 1
20 27800648 Treatment with a novel agent combining docosahexaenoate and metformin increases protectin DX and IL-6 production in skeletal muscle and reduces insulin resistance in obese diabetic db/db mice. 2017 Mar 1
21 28410530 Metformin attenuated endotoxin-induced acute myocarditis via activating AMPK. 2017 Jun 2
22 28921708 Scopoletin Supplementation Ameliorates Steatosis and Inflammation in Diabetic Mice. 2017 Nov 2
23 27059094 The role of metformin and resveratrol in the prevention of hypoxia-inducible factor 1α accumulation and fibrosis in hypoxic adipose tissue. 2016 Jun 1
24 27252117 The protective potential of metformin against acetaminophen-induced hepatotoxicity in BALB/C mice. 2016 Dec 1
25 25895126 Metformin prevents aggressive ovarian cancer growth driven by high-energy diet: similarity with calorie restriction. 2015 May 10 1
26 26303871 Interaction between metformin and leucine in reducing hyperlipidemia and hepatic lipid accumulation in diet-induced obese mice. 2015 Nov 1
27 24789104 Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis. 2014 4
28 24973221 Metformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction. 2014 Aug 15 4
29 24976178 Partial hepatic resistance to IL-6-induced inflammation develops in type 2 diabetic mice, while the anti-inflammatory effect of AMPK is maintained. 2014 Aug 5 1
30 25315906 Metformin attenuates blood-brain barrier disruption in mice following middle cerebral artery occlusion. 2014 Oct 15 1
31 24009539 Metformin Down-regulates TNF-α Secretion via Suppression of Scavenger Receptors in Macrophages. 2013 Aug 1
32 22349108 Metformin ameliorates IL-6-induced hepatic insulin resistance via induction of orphan nuclear receptor small heterodimer partner (SHP) in mouse models. 2012 May 5
33 20869956 Ursolic acid ameliorates thymic atrophy and hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice. 2010 Dec 5 1
34 21311678 Metformin Inhibits Isoproterenol-induced Cardiac Hypertrophy in Mice. 2010 Dec 1
35 18606228 Dehydroepiandrosterone and metformin modulate progesterone-induced blocking factor (PIBF), cyclooxygenase 2 (COX2) and cytokines in early pregnant mice. 2008 Sep 2
36 16229818 AICAR stimulates IL-6 production via p38 MAPK in cardiac fibroblasts in adult mice: a possible role for AMPK. 2005 Dec 2 1