| 1 |
34224815 | Biliverdin reductase as a target in drug research and development: Facts and hypotheses. | 2021 Aug 20 |
2 |
| 2 |
34924900 | Induction of cell apoptosis by biliverdin reductase inhibitor in MCF-7 and MDA-MB-468 breast cancer cell lines: Experimental and in silico studies. | 2021 |
1 |
| 3 |
32425592 | Biliverdin Reductase A (BLVRA) Promotes Colorectal Cancer Cell Progression by Activating the Wnt/β-Catenin Signaling Pathway. | 2020 |
2 |
| 4 |
30954759 | Bilin-metabolizing enzymes: site-specific reductions catalyzed by two different type of enzymes. | 2019 Dec |
5 |
| 5 |
31065010 | TLR4 counteracts BVRA signaling in human leukocytes via differential regulation of AMPK, mTORC1 and mTORC2. | 2019 May 7 |
2 |
| 6 |
31704097 | Biliverdin reductase deficiency triggers an endothelial-to-mesenchymal transition in human endothelial cells. | 2019 Dec 15 |
1 |
| 7 |
28708313 | Human biliverdin reductase regulates the molecular mechanism underlying cancer development. | 2018 Feb |
1 |
| 8 |
29249571 | Redox Functions of Heme Oxygenase-1 and Biliverdin Reductase in Diabetes. | 2018 Feb |
1 |
| 9 |
27166089 | Interaction of human biliverdin reductase with Akt/protein kinase B and phosphatidylinositol-dependent kinase 1 regulates glycogen synthase kinase 3 activity: a novel mechanism of Akt activation. | 2016 Aug |
2 |
| 10 |
27387768 | Protective role of biliverdin against bile acid-induced oxidative stress in liver cells. | 2016 Aug |
2 |
| 11 |
24095978 | The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: it's time for reconciliation. | 2014 Feb |
1 |
| 12 |
25196843 | Protein/protein interactions in the mammalian heme degradation pathway: heme oxygenase-2, cytochrome P450 reductase, and biliverdin reductase. | 2014 Oct 24 |
2 |
| 13 |
24113378 | Biliverdin reductase plays a crucial role in hypoxia-induced chemoresistance in human glioblastoma. | 2013 Nov 1 |
1 |
| 14 |
22438843 | Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase? | 2012 |
2 |
| 15 |
22438844 | Go green: the anti-inflammatory effects of biliverdin reductase. | 2012 |
3 |
| 16 |
22457648 | Physiological antioxidative network of the bilirubin system in aging and age-related diseases. | 2012 |
2 |
| 17 |
22584576 | The human biliverdin reductase-based peptide fragments and biliverdin regulate protein kinase Cδ activity: the peptides are inhibitors or substrate for the protein kinase C. | 2012 Jul 13 |
1 |
| 18 |
22823425 | Molecular modeling to provide insight into the substrate binding and catalytic mechanism of human biliverdin-IXα reductase. | 2012 Aug 16 |
3 |
| 19 |
21099244 | Biliverdin reductase A in the prevention of cellular senescence against oxidative stress. | 2011 Jan 31 |
2 |
| 20 |
21241799 | Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment. | 2011 Apr |
1 |
| 21 |
21278388 | A homozygous nonsense mutation (c.214C->A) in the biliverdin reductase alpha gene (BLVRA) results in accumulation of biliverdin during episodes of cholestasis. | 2011 Apr |
1 |
| 22 |
20410444 | Characterization of the human biliverdin reductase gene structure and regulatory elements: promoter activity is enhanced by hypoxia and suppressed by TNF-alpha-activated NF-kappaB. | 2010 Sep |
3 |
| 23 |
20430037 | Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1-evidence for direct and indirect antioxidant actions of bilirubin. | 2010 Aug |
2 |
| 24 |
20679134 | Human heme oxygenase-1 efficiently catabolizes heme in the absence of biliverdin reductase. | 2010 Nov |
1 |
| 25 |
20704544 | Potential application of biliverdin reductase and its fragments to modulate insulin/IGF-1/MAPK/PI3-K signaling pathways in therapeutic settings. | 2010 Dec |
1 |
| 26 |
19509285 | Cell surface biliverdin reductase mediates biliverdin-induced anti-inflammatory effects via phosphatidylinositol 3-kinase and Akt. | 2009 Aug 7 |
3 |
| 27 |
19614742 | The use of synthetic linear tetrapyrroles to probe the verdin sites of human biliverdin-IXalpha reductase and human biliverdin-IXbeta reductase. | 2009 Aug |
6 |
| 28 |
19690164 | Limited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductase. | 2009 Oct 23 |
2 |
| 29 |
18241201 | Computational and experimental studies on the catalytic mechanism of biliverdin-IXbeta reductase. | 2008 May 1 |
1 |
| 30 |
18276984 | Biliverdin reductase: new features of an old enzyme and its potential therapeutic significance. | 2008 Jan-Feb |
3 |
| 31 |
18395354 | Old biliverdin reductase: links to insulin resistance and may be a novel therapeutic target. | 2008 |
1 |
| 32 |
18412543 | Biliverdin reductase is a transporter of haem into the nucleus and is essential for regulation of HO-1 gene expression by haematin. | 2008 Aug 1 |
1 |
| 33 |
17919068 | Biliverdin reductase: PKC interaction at the cross-talk of MAPK and PI3K signaling pathways. | 2007 Dec |
1 |
| 34 |
16287987 | New insights into biliverdin reductase functions: linking heme metabolism to cell signaling. | 2005 Dec |
2 |
| 35 |
14988408 | Biliverdin reductase, a novel regulator for induction of activating transcription factor-2 and heme oxygenase-1. | 2004 May 7 |
2 |
| 36 |
15665804 | The presence of heme-oxygenase and biliverdin reductase in human cranial ganglia indicates a role for carbon monoxide in neural transmission. | 2004 Dec |
1 |
| 37 |
11773068 | Human biliverdin reductase is a leucine zipper-like DNA-binding protein and functions in transcriptional activation of heme oxygenase-1 by oxidative stress. | 2002 Mar 15 |
1 |
| 38 |
11909697 | Immunohistochemical localization of the antioxidant enzymes biliverdin reductase and heme oxygenase-2 in human and pig gastric fundus. | 2002 Apr 1 |
1 |
| 39 |
11224564 | Structure of human biliverdin IXbeta reductase, an early fetal bilirubin IXbeta producing enzyme. | 2001 Mar |
1 |
| 40 |
11224565 | Crystal structure of rat biliverdin reductase. | 2001 Mar |
2 |
| 41 |
11278740 | Human biliverdin reductase is autophosphorylated, and phosphorylation is required for bilirubin formation. | 2001 Apr 6 |
2 |
| 42 |
10957639 | Crystallization and preliminary X-ray diffraction analysis of a rat biliverdin reductase. | 2000 Sep |
2 |
| 43 |
8631357 | Human biliverdin IXalpha reductase is a zinc-metalloprotein. Characterization of purified and Escherichia coli expressed enzymes. | 1996 Jan 15 |
2 |
| 44 |
1417867 | The interplay between basicity, conformation, and enzymatic reduction in biliverdins. | 1992 Oct 15 |
5 |
| 45 |
2759328 | Biliverdin reductase activity in cattle, sheep, rabbits and rats. | 1989 |
1 |