Cadmium

AKT serine/threonine kinase 1 ; Homo sapiens







46 Article(s)
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1 34903601 Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma. 2022 Feb 15 3
2 35524288 Melatonin modulates Nrf2 activity to protect porcine pre-pubertal Sertoli cells from the abnormal H2 O2 generation and reductive stress effects of cadmium. 2022 May 6 2
3 35616841 Cadmium induces apoptosis by miR-9-5p targeting PTEN and regulates the PI3K/AKT pathway in the piglet adrenal gland. 2022 May 26 2
4 32858297 Cadmium exposure triggers osteoporosis in duck via P2X7/PI3K/AKT-mediated osteoblast and osteoclast differentiation. 2021 Jan 1 3
5 33433347 Cadmium and molybdenum co-induce pyroptosis via ROS/PTEN/PI3K/AKT axis in duck renal tubular epithelial cells. 2021 Mar 1 2
6 34081812 CircSPAG16 suppresses cadmium-induced transformation of human bronchial epithelial cells by decoying PIP5K1α to inactivate Akt. 2021 Aug 2
7 34134961 [Luteolin has a significant protective effect against cadmium-induced injury in lung epithelial Beas-2B cells]. 2021 May 20 1
8 34668346 Resveratrol ameliorates toxic effects of cadmium on placental development in mouse placenta and human trophoblast cells. 2021 Dec 1 1
9 32061436 Cadmium exposure enhances organic cation transporter 2 trafficking to the kidney membrane and exacerbates cisplatin nephrotoxicity. 2020 Apr 1
10 32512147 Cadmium exposure activates Akt/ERK Signaling and pro-inflammatory COX-2 expression in human gallbladder epithelial cells via a ROS dependent mechanism. 2020 Sep 1
11 33075233 Cadmium induces CCL2 production in glioblastoma cells via activation of MAPK, PI3K, and PKC pathways. 2020 Dec 1
12 33129824 Role of the PI3K/Akt pathway in cadmium induced malignant transformation of normal prostate epithelial cells. 2020 Dec 15 3
13 30324847 AKT inhibition-mediated dephosphorylation of TFE3 promotes overactive autophagy independent of MTORC1 in cadmium-exposed bone mesenchymal stem cells. 2019 Apr 4
14 30804470 Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms. 2019 Nov 2
15 31120230 Cadmium Induces Migration of Colon Cancer Cells: Roles of Reactive Oxygen Species, P38 and Cyclooxygenase-2. 2019 2
16 31562949 Carvacrol inhibits cadmium toxicity through combating against caspase dependent/independent apoptosis in PC12 cells. 2019 Dec 2
17 29444456 Gap junctional intercellular communication and endoplasmic reticulum stress regulate chronic cadmium exposure induced apoptosis in HK-2 cells. 2018 May 15 5
18 29563926 GSK-3β-mediated regulation of cadmium-induced cell death and survival. 2018 5
19 30107323 FcγRIIB receptor-mediated apoptosis in macrophages through interplay of cadmium sulfide nanomaterials and protein corona. 2018 Nov 30 2
20 27891586 Celastrol Attenuates Cadmium-Induced Neuronal Apoptosis via Inhibiting Ca2+ -CaMKII-Dependent Akt/mTOR Pathway. 2017 Aug 6
21 27940299 GPER/ERK&AKT/NF-κB pathway is involved in cadmium-induced proliferation, invasion and migration of GPER-positive thyroid cancer cells. 2017 Feb 15 4
22 28302721 Involvement of Notch1 signaling in malignant progression of A549 cells subjected to prolonged cadmium exposure. 2017 May 12 1
23 28353032 α-Synuclein Enhances Cadmium Uptake and Neurotoxicity via Oxidative Stress and Caspase Activated Cell Death Mechanisms in a Dopaminergic Cell Model of Parkinson's Disease. 2017 Aug 1
24 28450285 Low-dose cadmium exposure induces peribronchiolar fibrosis through site-specific phosphorylation of vimentin. 2017 Jul 1 2
25 28651161 Connexin 43 mediates changes in protein phosphorylation in HK-2 cells during chronic cadmium exposure. 2017 Jul 1
26 29157834 16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells. 2017 Dec 1 1
27 26716417 Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. 2016 Feb 2 1
28 26751215 Cadmium Activates Multiple Signaling Pathways That Coordinately Stimulate Akt Activity to Enhance c-Myc mRNA Stability. 2016 1
29 26002629 Rapamycin prevents cadmium-induced neuronal cell death via targeting both mTORC1 and mTORC2 pathways. 2015 Oct 1
30 26046303 Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium. 2015 Aug 28 5
31 26182376 Cadmium toxicity induces ER stress and apoptosis via impairing energy homoeostasis in cardiomyocytes. 2015 Apr 10 1
32 26248512 Calcium Signaling Involvement in Cadmium-Induced Astrocyte Cytotoxicity and Cell Death Through Activation of MAPK and PI3K/Akt Signaling Pathways. 2015 Sep 7
33 26385184 Cadmium promotes the proliferation of triple-negative breast cancer cells through EGFR-mediated cell cycle regulation. 2015 Nov 15 1
34 26514923 Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells. 2015 Dec 2 4
35 24111524 Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network. 2014 Jan 5
36 25118938 Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells. 2014 Aug 14 1
37 23673518 Phosphorylation of FOXO3a by PI3K/Akt pathway in HK-2 renal proximal tubular epithelial cells exposed to cadmium. 2013 Dec 3
38 21984483 Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells. 2012 Jan 4
39 22011313 Metalloestrogenic effects of quantum dots. 2012 Jan 1
40 22884995 Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling. 2012 Oct 15 3
41 21195169 Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death. 2011 Mar 1 1
42 21787718 Cadmium-induced up-regulation of aldo-keto reductase 1C3 expression in human nasal septum carcinoma RPMI-2650 cells: Involvement of reactive oxygen species and phosphatidylinositol 3-kinase/Akt. 2011 May 1
43 19557366 Cadmium adaptation is regulated by multidrug resistance-associated protein-mediated Akt pathway and metallothionein induction. 2009 Jun 3
44 18275979 Rapid activation of ERK1/2 and AKT in human breast cancer cells by cadmium. 2008 May 1 5
45 17125913 Cadmium induces mitogenic signaling in breast cancer cell by an ERalpha-dependent mechanism. 2007 Jan 29 3
46 17514353 Calcium-mediated activation of PI3K and p53 leads to apoptosis in thyroid carcinoma cells. 2007 Jun 7