Oxaliplatin

AKT serine/threonine kinase 1 ; Homo sapiens







46 Article(s)
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1 32914380 MiR-325 Promotes Oxaliplatin-Induced Cytotoxicity Against Colorectal Cancer Through the HSPA12B/PI3K/AKT/Bcl-2 Pathway. 2021 Aug 2
2 33574948 Identification of AKT1/β-catenin mutations conferring cetuximab and chemotherapeutic drug resistance in colorectal cancer treatment. 2021 Mar 1
3 33578797 SILAC-Based Quantitative Proteomic Analysis of Oxaliplatin-Resistant Pancreatic Cancer Cells. 2021 Feb 10 1
4 33653494 Oxaliplatin and Gedatolisib (PKI-587) Co-Loaded Hollow Polydopamine Nano-Shells with Simultaneous Upstream and Downstream Action to Re-Sensitize Drugs-Resistant Hepatocellular Carcinoma to Chemotherapy. 2021 Jan 1 3
5 33662352 Perifosine enhances the potential antitumor effect of 5-fluorourasil and oxaliplatin in colon cancer cells harboring the PIK3CA mutation. 2021 May 5 4
6 33963708 [Synergistic effect of polysaccharide from Trichoderma pseudokoningii and oxaliplatin on colorectal cancer cells in vitro]. 2021 Apr 20 1
7 33982772 LY‑294002 enhances the chemosensitivity of liver cancer to oxaliplatin by blocking the PI3K/AKT/HIF‑1α pathway. 2021 Jul 4
8 33986248 A KLF4/PiHL/EZH2/HMGA2 regulatory axis and its function in promoting oxaliplatin-resistance of colorectal cancer. 2021 May 13 1
9 34017210 MicroRNA-19b Downregulates NR3C1 and Enhances Oxaliplatin Chemoresistance in Colon Cancer via the PI3K/AKT/mTOR Pathway. 2021 2
10 34017681 MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer. 2021 1
11 34052504 The tyrosine phosphatase SHP2 promotes proliferation and oxaliplatin resistance of colon cancer cells through AKT and ERK. 2021 Jul 23 4
12 34193174 SRPK1/AKT axis promotes oxaliplatin-induced anti-apoptosis via NF-κB activation in colon cancer. 2021 Jun 30 1
13 34477047 RecQ-like helicase 4 (RECQL4) exacerbates resistance to oxaliplatin in colon adenocarcinoma via activation of the PI3K/AKT signaling pathway. 2021 Dec 1
14 34750753 Kaempferol sensitizes cell proliferation inhibition in oxaliplatin-resistant colon cancer cells. 2021 Dec 1
15 31972222 A role for ceramide glycosylation in resistance to oxaliplatin in colorectal cancer. 2020 Mar 15 1
16 32209726 Inhibition of miR-19a partially reversed the resistance of colorectal cancer to oxaliplatin via PTEN/PI3K/AKT pathway. 2020 Mar 25 2
17 32331534 The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1. 2020 Sep 1 2
18 32818544 GOLPH3 inhibition reverses oxaliplatin resistance of colon cancer cells via suppression of PI3K/AKT/mTOR pathway. 2020 Nov 1 3
19 30468657 Nobiletin sensitizes colorectal cancer cells to oxaliplatin by PI3K/Akt/MTOR pathway. 2019 Jan 1 1
20 30672917 Cyanidin inhibits EMT induced by oxaliplatin via targeting the PDK1-PI3K/Akt signaling pathway. 2019 Feb 20 1
21 30926638 RAC1b Overexpression Confers Resistance to Chemotherapy Treatment in Colorectal Cancer. 2019 May 2
22 31423282 Response prediction to oxaliplatin plus 5-fluorouracil chemotherapy in patients with colorectal cancer using a four-protein immunohistochemical model. 2019 Aug 2
23 31497229 PKI-587 enhances chemosensitivity of oxaliplatin in hepatocellular carcinoma through suppressing DNA damage repair pathway (NHEJ and HR) and PI3K/AKT/mTOR pathway. 2019 2
24 29115606 DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53‑deficient pancreatic cancer cells. 2018 Jan 2
25 29378575 Effects of Omegaven®, EPA, DHA and oxaliplatin on oesophageal adenocarcinoma cell lines growth, cytokine and cell signal biomarkers expression. 2018 Jan 30 1
26 29497313 Knockdown of KLK11 reverses oxaliplatin resistance by inhibiting proliferation and activating apoptosis via suppressing the PI3K/AKT signal pathway in colorectal cancer cell. 2018 5
27 29721050 Secretory Clusterin Mediates Oxaliplatin Resistance via the Gadd45a/PI3K/Akt Signaling Pathway in Hepatocellular Carcinoma. 2018 1
28 29737584 Metformin increases the cytotoxicity of oxaliplatin in human DLD-1 colorectal cancer cells through down-regulating HMGB1 expression. 2018 Aug 1
29 29844803 Sphingosine kinase 1 overexpression is associated with poor prognosis and oxaliplatin resistance in hepatocellular carcinoma. 2018 Jun 1
30 28463955 Capilliposide C Sensitizes Esophageal Squamous Carcinoma Cells to Oxaliplatin by Inducing Apoptosis Through the PI3K/Akt/mTOR Pathway. 2017 May 2 3
31 28621236 Dynamic soluble changes in sVEGFR1, HGF, and VEGF promote chemotherapy and bevacizumab resistance: A prospective translational study in the BECOX (GEMCAD 09-01) trial. 2017 Jun 1
32 26733168 Reactive oxygen species mediate oxaliplatin-induced epithelial-mesenchymal transition and invasive potential in colon cancer. 2016 Jun 1
33 27091625 Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway. 2016 Apr 19 1
34 27245421 Stanniocalcin 2 induces oxaliplatin resistance in colorectal cancer cells by upregulating P-glycoprotein. 2016 Sep 1
35 27633443 Linc00152 Functions as a Competing Endogenous RNA to Confer Oxaliplatin Resistance and Holds Prognostic Values in Colon Cancer. 2016 Dec 2
36 25444914 Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells. 2015 Feb 1 2
37 25777765 Nitrogen permease regulator-like 2 enhances sensitivity to oxaliplatin in colon cancer cells. 2015 Jul 1
38 23279642 Secretory clusterin contributes to oxaliplatin resistance by activating Akt pathway in hepatocellular carcinoma. 2013 Mar 1
39 21245990 LY294002 potentiates the anti-cancer effect of oxaliplatin for gastric cancer via death receptor pathway. 2011 Jan 14 3
40 21718595 Protective autophagy antagonizes oxaliplatin-induced apoptosis in gastric cancer cells. 2011 Jul 1
41 22811824 Insulin caused drug resistance to oxaliplatin in colon cancer cell line HT29. 2011 Mar 2
42 19128511 Inhibition of PI3K increases oxaliplatin sensitivity in cholangiocarcinoma cells. 2009 Jan 8 1
43 19240026 Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation. 2009 Apr 17 1
44 18767116 Overexpression of cFLIPs inhibits oxaliplatin-mediated apoptosis through enhanced XIAP stability and Akt activation in human renal cancer cells. 2008 Nov 1 3
45 18790786 Effect of chemotherapeutic stress on induction of vascular endothelial growth factor family members and receptors in human colorectal cancer cells. 2008 Sep 2
46 16891475 Sequence-dependent inhibition of human colon cancer cell growth and of prosurvival pathways by oxaliplatin in combination with ZD6474 (Zactima), an inhibitor of VEGFR and EGFR tyrosine kinases. 2006 Jul 1