Paclitaxel

AKT serine/threonine kinase 1 ; Homo sapiens







196 Article(s)
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1 34535390 Radix Tetrastigma Extracts Enhance the Chemosensitivity in Triple-Negative Breast Cancer Via Inhibiting PI3K/Akt/mTOR-Mediated Autophagy. 2022 Feb 2
2 34837170 AZD4547 targets the FGFR/Akt/SOX2 axis to overcome paclitaxel resistance in head and neck cancer. 2022 Feb 2
3 35122700 Circulating tumor DNA predicts efficacy of a dual AKT/p70S6K inhibitor (LY2780301) plus paclitaxel in metastatic breast cancer: plasma analysis of the TAKTIC phase IB/II study. 2022 May 1
4 35440807 Exosomal PD-L1 confers chemoresistance and promotes tumorigenic properties in esophageal cancer cells via upregulating STAT3/miR-21. 2022 Apr 19 1
5 35531363 Response to anti-DKK1 therapy in uterine carcinosarcoma: A case report. 2022 Feb 1
6 35588308 GAS6-AXL inhibition by AVB-500 overcomes resistance to paclitaxel in endometrial cancer by decreasing tumor cell glycolysis. 2022 May 19 1
7 33436648 Integrative microRNA and gene expression analysis identifies new epigenetically regulated microRNAs mediating taxane resistance in ovarian cancer. 2021 Jan 12 1
8 33556340 TLR4/IL-6/IRF1 signaling regulates androgen receptor expression: A potential therapeutic target to overcome taxol resistance in ovarian cancer. 2021 Apr 2
9 33613708 Paclitaxel increases the sensitivity of lung cancer cells to lobaplatin via PI3K/Akt pathway. 2021 Mar 1
10 33738259 Heat Shock Protein 90 Triggers Multi-Drug Resistance of Ovarian Cancer via AKT/GSK3β/β-Catenin Signaling. 2021 2
11 33764366 CCL26 is upregulated by nab-paclitaxel in pancreatic cancer-associated fibroblasts and promotes PDAC invasiveness through activation of the PI3K/AKT/mTOR pathway. 2021 Apr 15 1
12 33809079 GBP5 Serves as a Potential Marker to Predict a Favorable Response in Triple-Negative Breast Cancer Patients Receiving a Taxane-Based Chemotherapy. 2021 Mar 12 1
13 33848578 Synergistic effects of green tea extract and paclitaxel in the induction of mitochondrial apoptosis in ovarian cancer cell lines. 2021 Jun 30 1
14 34145425 MiR-181c sensitizes ovarian cancer cells to paclitaxel by targeting GRP78 through the PI3K/Akt pathway. 2021 Jun 18 2
15 34229754 Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α-AKT-mTOR pathway in esophageal squamous cell carcinoma. 2021 Jul 6 3
16 34338752 Correction: LncRNA HOTAIR contributes Taxol-resistance of hepatocellular carcinoma cells via activating AKT phosphorylation by down-regulating miR-34a. 2021 Aug 27 1
17 34479917 Paclitaxel Impedes EGFR-mutated PC9 Cell Growth via Reactive Oxygen Species-mediated DNA Damage and EGFR/PI3K/AKT/mTOR Signaling Pathway Suppression. 2021 Sep-Oct 2
18 34512368 Targeting Autophagy with Natural Compounds in Cancer: A Renewed Perspective from Molecular Mechanisms to Targeted Therapy. 2021 1
19 34584572 Targeting Mps1 in combination with paclitaxel inhibits osteosarcoma progression by modulating spindle assembly checkpoint and Akt/mTOR signaling. 2021 Nov 3
20 34761351 The combined therapy of miR-383-5p restoration and paclitaxel for treating MDA-MB-231 breast cancer. 2021 Nov 10 1
21 34768915 Ursolic Acid Accelerates Paclitaxel-Induced Cell Death in Esophageal Cancer Cells by Suppressing Akt/FOXM1 Signaling Cascade. 2021 Oct 25 3
22 34847067 Correction for: Overexpressed ITGA2 contributes to paclitaxel resistance by ovarian cancer cells through the activation of the AKT/FoxO1 pathway. 2021 Nov 30 1
23 34915631 [Effect and mechanism of siRNA targeting α-enolase gene combined with paclitaxel on proliferation, invasion and apoptosis of hepatocellular carcinoma cell]. 2021 Dec 23 3
24 31648639 Functionalization of Silver Nanoparticles Loaded with Paclitaxel-induced A549 Cells Apoptosis Through ROS-Mediated Signaling Pathways 2020 1
25 31783010 Overcoming Taxol-resistance in A549 cells: A comprehensive strategy of targeting P-gp transporter, AKT/ERK pathways, and cytochrome P450 enzyme CYP1B1 by 4-hydroxyemodin. 2020 Jan 1
26 31841354 Capivasertib Plus Paclitaxel Versus Placebo Plus Paclitaxel As First-Line Therapy for Metastatic Triple-Negative Breast Cancer: The PAKT Trial. 2020 Feb 10 1
27 32110051 Knockdown of FOXO6 Inhibits Glycolysis and Reduces Cell Resistance to Paclitaxel in HCC Cells via PI3K/Akt Signaling Pathway. 2020 1
28 32194871 Bioinspired tumor-homing nanoplatform for co-delivery of paclitaxel and siRNA-E7 to HPV-related cervical malignancies for synergistic therapy. 2020 2
29 32202508 Overexpressed ITGA2 contributes to paclitaxel resistance by ovarian cancer cells through the activation of the AKT/FoxO1 pathway. 2020 Mar 22 2
30 32268876 Shikonin suppresses NEAT1 and Akt signaling in treating paclitaxel-resistant non-small cell of lung cancer. 2020 Apr 8 2
31 32452013 Interleukin-22 enhances chemoresistance of lung adenocarcinoma cells to paclitaxel. 2020 Jul 1
32 32494162 MiR-153-5p Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Paclitaxel by Inducing G2M Phase Arrest. 2020 1
33 32554905 CRISPR-mediated knockdown of miR-214 modulates cell fate in response to anti-cancer drugs in HPV-negative and HPVpositive cervical cancer cells. 2020 1
34 32700738 LncRNA HOTAIR contributes Taxol-resistance of hepatocellular carcinoma cells via activating AKT phosphorylation by down-regulating miR-34a. 2020 Jul 31 2
35 32805372 YAN, a novel microtubule inhibitor, inhibits P-gp and MRP1 function and induces mitotic slippage followed by apoptosis in multidrug-resistant A549/Taxol cells. 2020 Dec 1
36 33019717 Specific c-Jun N-Terminal Kinase Inhibitor, JNK-IN-8 Suppresses Mesenchymal Profile of PTX-Resistant MCF-7 Cells through Modulating PI3K/Akt, MAPK and Wnt Signaling Pathways. 2020 Oct 1 2
37 33102192 Induction of apoptosis and role of paclitaxel-loaded hyaluronic acid-crosslinked nanoparticles in the regulation of AKT and RhoA. 2020 Jul-Sep 1
38 33165766 Paclitaxel-Loaded Colloidal Silica and TPGS-Based Solid Self-Emulsifying System Interferes Akt/mTOR Pathway in MDA-MB-231 and Demonstrates Anti-tumor Effect in Syngeneic Mammary Tumors. 2020 Nov 9 1
39 33218396 Inhibitory effects of everolimus in combination with paclitaxel on adriamycin-resistant breast cancer cell line MDA-MB-231. 2020 Nov 2
40 33256016 Sitagliptin Modulates the Response of Ovarian Cancer Cells to Chemotherapeutic Agents. 2020 Nov 26 1
41 33269821 Paclitaxel inhibits proliferation and invasion and promotes apoptosis of breast cancer cells by blocking activation of the PI3K/AKT signaling pathway. 2020 Nov 6
42 33292283 Resveratrol, curcumin, paclitaxel and miRNAs mediated regulation of PI3K/Akt/mTOR pathway: go four better to treat bladder cancer. 2020 Nov 23 1
43 33817712 Adjuvant effects of chemotherapeutics and Metformin on MFE-319 endometrial carcinoma cell line. 2020 Jul-Sep 1
44 30563934 Phase IB Dose Escalation and Expansion Study of AKT Inhibitor Afuresertib with Carboplatin and Paclitaxel in Recurrent Platinum-resistant Ovarian Cancer. 2019 Mar 1 1
45 30782035 NEAT1 mediates paclitaxel-resistance of non-small cell of lung cancer through activation of Akt/mTOR signalling pathway. 2019 Dec 1
46 30863067 Improving the anti-keloid outcomes through liposomes loading paclitaxel-cholesterol complexes. 2019 1
47 30866697 Dasatinib can enhance paclitaxel and gemcitabine inhibitory activity in human pancreatic cancer cells. 2019 1
48 31098863 Inhibiting casein kinase 2 overcomes paclitaxel resistance in gastric cancer. 2019 Nov 1
49 31136990 Resveratrol enhances chemosensitivity of renal cell carcinoma to paclitaxel. 2019 Jun 1 1
50 31197964 Pectasol-C Modified Citrus Pectin targets Galectin-3-induced STAT3 activation and synergize paclitaxel cytotoxic effect on ovarian cancer spheroids. 2019 Aug 1