N-Methylaspartate

AKT serine/threonine kinase 1 ; Homo sapiens







29 Article(s)
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1 32892226 Kukoamine A Protects against NMDA-Induced Neurotoxicity Accompanied with Down-Regulation of GluN2B-Containing NMDA Receptors and Phosphorylation of PI3K/Akt/GSK-3β Signaling Pathway in Cultured Primary Cortical Neurons. 2020 Nov 3
2 31201887 Neuroprotective effect of catechins derivatives isolated from Anhua dark tea on NMDA-induced excitotoxicity in SH-SY5Y cells. 2019 Sep 1
3 28484273 Role of Akt-independent mTORC1 and GSK3β signaling in sublethal NMDA-induced injury and the recovery of neuronal electrophysiology and survival. 2017 May 8 3
4 27140692 Prokineticins are neuroprotective in models of cerebral ischemia and ischemic tolerance in vitro. 2016 Sep 1
5 27430327 Propofol protects hippocampal neurons from apoptosis in ischemic brain injury by increasing GLT-1 expression and inhibiting the activation of NMDAR via the JNK/Akt signaling pathway. 2016 Sep 1
6 24523415 Ras protein activation is a key event in activity-dependent survival of cerebellar granule neurons. 2014 Mar 21 4
7 24595404 Soluble beta-amyloid peptides, but not insoluble fibrils, have specific effect on neuronal microRNA expression. 2014 1
8 24604717 IGF-1 alleviates NMDA-induced excitotoxicity in cultured hippocampal neurons against autophagy via the NR2B/PI3K-AKT-mTOR pathway. 2014 Nov 1
9 23161148 Neuroprotection of interleukin-6 against NMDA-induced neurotoxicity is mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT signaling pathways. 2013 Mar 1
10 23958999 Nitric oxide regulates AKT phosphorylation and nuclear translocation in cultured retinal cells. 2013 Dec 1
11 22836274 Neuronal stimulation induces autophagy in hippocampal neurons that is involved in AMPA receptor degradation after chemical long-term depression. 2012 Jul 25 1
12 23077075 Dual effect of 17β-estradiol on NMDA-induced neuronal death: involvement of metabotropic glutamate receptor 1. 2012 Dec 1
13 20717763 Neuroprotection of interleukin-6 against NMDA-induced apoptosis and its signal-transduction mechanisms. 2011 Apr 1
14 21490677 Cell-type-specific regulation of raft-associated Akt signaling. 2011 Apr 14 1
15 21597037 Glutamatergic signaling maintains the epithelial phenotype of proximal tubular cells. 2011 Jun 2
16 19766294 Role of NMDA receptor in homocysteine-induced activation of mitogen-activated protein kinase and phosphatidyl inositol 3-kinase pathways in cultured human vascular smooth muscle cells. 2010 Feb 1
17 20026151 Striatal Akt/GSK3 signaling pathway in the development of L-Dopa-induced dyskinesias in MPTP monkeys. 2010 Apr 16 1
18 20043967 Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase. 2010 Mar 2
19 19462233 Different mechanisms of NMDA-mediated protection against neuronal apoptosis: a stimuli-dependent effect. 2009 Nov 1
20 17893911 Growth-compromised HSV-2 vector Delta RR protects from N-methyl-D-aspartate-induced neuronal degeneration through redundant activation of the MEK/ERK and PI3-K/Akt survival pathways, either one of which overrides apoptotic cascades. 2008 Feb 1 1
21 17401440 Cell signaling pathways in the mechanisms of neuroprotection afforded by bergamot essential oil against NMDA-induced cell death in vitro. 2007 Jun 2
22 17492691 Subtoxic N-methyl-D-aspartate delayed neuronal death in ischemic brain injury through TrkB receptor- and calmodulin-mediated PI-3K/Akt pathway activation. 2007 6
23 17714450 A role for polyamines in retinal ganglion cell excitotoxic death. 2007 Nov 1
24 16621159 Modulation of NMDA receptors by AKT kinase. 2006 Sep 1
25 16641230 Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitability. 2006 Apr 26 2
26 14504398 Akt as a mediator of cell death. 2003 Sep 30 2
27 12373512 Co-activation of the phosphatidylinositol-3-kinase/Akt signaling pathway by N-methyl-D-aspartate and TrkB receptors in cerebellar granule cell neurons. 2002 7
28 10212287 Brain-derived neurotrophic factor mediates the anti-apoptotic effect of NMDA in cerebellar granule neurons: signal transduction cascades and site of ethanol action. 1999 May 1 1
29 9859994 Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway. 1998 Dec 10 1