| 1 |
31885313 | Binding of Avibirnavirus VP3 to the PIK3C3-PDPK1 complex inhibits autophagy by activating the AKT-MTOR pathway. | 2020 Sep |
2 |
| 2 |
31554835 | GRK2 promotes growth of medulloblastoma cells and protects them from chemotherapy-induced apoptosis. | 2019 Sep 25 |
1 |
| 3 |
29309885 | HBXIP regulates etoposide-induced cell cycle checkpoints and apoptosis in MCF-7 human breast carcinoma cells. | 2018 Mar 20 |
1 |
| 4 |
29953987 | 17-(Allylamino)-17-Demethoxygeldanamycin Enhances Etoposide-Induced Cytotoxicity via the Downregulation of Xeroderma Pigmentosum Complementation Group C Expression in Human Lung Squamous Cell Carcinoma Cells. | 2018 |
4 |
| 5 |
30121250 | JNK-AKT-NF-κB controls P-glycoprotein expression to attenuate the cytotoxicity of deoxynivalenol in mammalian cells. | 2018 Oct |
1 |
| 6 |
24038446 | Phosphorylation of Smac by Akt promotes the caspase-3 activation during etoposide-induced apoptosis in HeLa cells. | 2015 Feb |
3 |
| 7 |
25543088 | Regulation and function of Myb-binding protein 1A (MYBBP1A) in cellular senescence and pathogenesis of head and neck cancer. | 2015 Mar 28 |
1 |
| 8 |
25954860 | Low expression of phosphatase and tensin homolog in clear‑cell renal cell carcinoma contributes to chemoresistance through activating the Akt/HDM2 signaling pathway. | 2015 Aug |
1 |
| 9 |
26046675 | Resveratrol Enhances Etoposide-Induced Cytotoxicity through Down-Regulating ERK1/2 and AKT-Mediated X-ray Repair Cross-Complement Group 1 (XRCC1) Protein Expression in Human Non-Small-Cell Lung Cancer Cells. | 2015 Dec |
5 |
| 10 |
26232556 | Erythropoietin protects neuroblastoma cells against etoposide and vincristine by activating ERK and AKT pathways but has no effect in kidney cells. | 2015 Sep 15 |
1 |
| 11 |
26458825 | Akt is translocated to the mitochondria during etoposide-induced apoptosis of HeLa cells. | 2015 Nov |
7 |
| 12 |
24569089 | Context-dependent antagonism between Akt inhibitors and topoisomerase poisons. | 2014 May |
1 |
| 13 |
22488521 | Attenuation of PTEN perturbs genomic stability via activation of Akt and down-regulation of Rad51 in human embryonic kidney cells. | 2013 Aug |
1 |
| 14 |
23579276 | p38MAPK inhibition: a new combined approach to reduce neuroblastoma resistance under etoposide treatment. | 2013 Apr 11 |
1 |
| 15 |
23796964 | Multinucleation regulated by the Akt/PTEN signaling pathway is a survival strategy for HepG2 cells. | 2013 Aug 15 |
3 |
| 16 |
24260231 | Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis. | 2013 |
1 |
| 17 |
23093908 | Bid-overexpression regulates proliferation and phosphorylation of Akt and MAPKs in response to etoposide-induced DNA damage in hepatocellular carcinoma cells. | 2012 |
3 |
| 18 |
21325296 | ICER evokes Dusp1-p38 pathway enhancing chemotherapy sensitivity in myeloid leukemia. | 2011 Feb 15 |
1 |
| 19 |
21617849 | Aspirin reduces the apoptotic effect of etoposide via Akt activation and up-regulation of p21(cip). | 2011 Oct |
1 |
| 20 |
21730367 | Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy. | 2011 Jul |
7 |
| 21 |
21784088 | Inactivation of PTEN is responsible for the survival of Hep G2 cells in response to etoposide-induced damage. | 2011 Oct 1 |
4 |
| 22 |
20338106 | Nicotine induces resistance to chemotherapy in nasal epithelial cancer. | 2010 Mar-Apr |
1 |
| 23 |
20369051 | Maspin suppresses survival of lung cancer cells through modulation of Akt pathway. | 2010 Mar |
1 |
| 24 |
19212674 | Synergistic cell growth inhibition by the combination of amrubicin and Akt-suppressing tyrosine kinase inhibitors in small cell lung cancer cells: implication of c-Src and its inhibitor. | 2009 Mar |
3 |
| 25 |
17935137 | Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death. | 2008 Jan 15 |
2 |
| 26 |
18695355 | AG490, a Jak2-specific inhibitor, induces osteoclast survival by activating the Akt and ERK signaling pathways. | 2008 Nov 30 |
1 |
| 27 |
16778834 | Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death. | 2007 Feb |
1 |
| 28 |
17699715 | Selective cell death of oncogenic Akt-transduced brain cancer cells by etoposide through reactive oxygen species mediated damage. | 2007 Aug |
7 |
| 29 |
16424010 | Phospholipase D prevents etoposide-induced apoptosis by inhibiting the expression of early growth response-1 and phosphatase and tensin homologue deleted on chromosome 10. | 2006 Jan 15 |
2 |
| 30 |
16427189 | Hypoxia confers protection against apoptosis via PI3K/Akt and ERK pathways in lung cancer cells. | 2006 Oct 28 |
2 |
| 31 |
16527552 | Activation of Akt and ERK signalling pathways induced by etoposide confer chemoresistance in gastric cancer cells. | 2006 May |
2 |
| 32 |
16721826 | Different signaling responses to anti-proliferative agents in human aortic and venous smooth muscle cells. | 2006 Oct 15 |
1 |
| 33 |
15674326 | Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis. | 2005 Mar 17 |
4 |
| 34 |
15703783 | PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways. | 2005 Apr |
1 |
| 35 |
16267399 | PI3-kinase and PDK-1 regulate HDAC1-mediated transcriptional repression of transcription factor NF-kappaB. | 2005 Oct 31 |
1 |
| 36 |
15287952 | Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway. | 2004 Aug |
1 |
| 37 |
12761490 | HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells. | 2003 May 22 |
1 |
| 38 |
12869645 | Aspirin protects Caco-2 cells from apoptosis after serum deprivation through the activation of a phosphatidylinositol 3-kinase/AKT/p21Cip/WAF1pathway. | 2003 Aug |
1 |
| 39 |
12970779 | A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells. | 2003 Sep |
1 |
| 40 |
11864976 | The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. | 2002 May 10 |
1 |
| 41 |
11896462 | A novel conditional Akt 'survival switch' reversibly protects cells from apoptosis. | 2002 Feb |
1 |
| 42 |
12481412 | Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy. | 2002 Sep |
1 |
| 43 |
10669740 | Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB. | 2000 Mar |
1 |