Flavonoids

AKT serine/threonine kinase 1 ; Homo sapiens







67 Article(s)
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1 33442914 The interplay of ROS and the PI3K/Akt pathway in autophagy regulation. 2022 Feb 2
2 34856476 Cardioprotective effects of phytopigments via multiple signaling pathways. 2022 Jan 1
3 35045245 Redox Activity of Flavonoids: Impact on Human Health, Therapeutics, and Chemical Safety. 2022 Feb 21 1
4 35140796 The Mechanism Study of Common Flavonoids on Antiglioma Based on Network Pharmacology and Molecular Docking. 2022 1
5 35586809 Inhibitory Effect of Lotus Leaf-Enriched Flavonoid Extract on the Growth of HT-29 Colon Cancer Cells through the Expression of PI3K-Related Molecules. 2022 2
6 33167824 mTOR Targeted Cancer Chemoprevention by Flavonoids. 2021 1
7 33246112 Molecular mechanisms underlying the anticancer activities of licorice flavonoids. 2021 Mar 1 1
8 33609662 Prenylated flavonoids from Ficus hirta induces HeLa cells apoptosis via MAPK and AKT signaling pathways. 2021 Apr 15 1
9 33647348 Acacetin and pinostrobin as a promising inhibitor of cancer-associated protein kinases. 2021 May 1
10 33918053 Effect of Quercetin on ABCC6 Transporter: Implication in HepG2 Migration. 2021 Apr 8 1
11 33995548 Total Flavonoids of Rhizoma Drynariae Restore the MMP/TIMP Balance in Models of Osteoarthritis by Inhibiting the Activation of the NF-κB and PI3K/AKT Pathways. 2021 1
12 34149918 Flavonoid GL-V9 suppresses invasion and migration of human colorectal cancer cells by inhibiting PI3K/Akt and MMP-2/9 signaling. 2021 1
13 34333340 Wound healing properties of flavonoids: A systematic review highlighting the mechanisms of action. 2021 Sep 1
14 34348607 Flavonoids and PI3K/Akt/mTOR Signaling Cascade: A Potential Crosstalk in Anticancer Treatment. 2021 2
15 34641354 STL1, a New AKT Inhibitor, Synergizes with Flavonoid Quercetin in Enhancing Cell Death in A Chronic Lymphocytic Leukemia Cell Line. 2021 Sep 25 1
16 34727985 Simulation studies, 3D QSAR and molecular docking on a point mutation of protein kinase B with flavonoids targeting ovarian Cancer. 2021 Nov 2 1
17 34745273 Explore the Lipid-Lowering and Weight-Reducing Mechanism of Lotus Leaf Based on Network Pharmacology and Molecular Docking. 2021 1
18 34830339 Targeting PI3K/Akt/mTOR Pathway by Different Flavonoids: A Cancer Chemopreventive Approach. 2021 Nov 18 2
19 32165083 Inhibition of herpes simplex virus by myricetin through targeting viral gD protein and cellular EGFR/PI3K/Akt pathway. 2020 May 1
20 32257052 RNA-seq data analysis of stimulated hepatocellular carcinoma cells treated with epigallocatechin gallate and fisetin reveals target genes and action mechanisms. 2020 1
21 32635299 Control of Reactive Oxygen Species for the Prevention of Parkinson's Disease: The Possible Application of Flavonoids. 2020 Jul 3 1
22 33143000 The Synthetic Flavonoid Derivative GL-V9 Induces Apoptosis and Autophagy in Cutaneous Squamous Cell Carcinoma via Suppressing AKT-Regulated HK2 and mTOR Signals. 2020 Oct 30 1
23 30551400 Phytochemicals and cognitive health: Are flavonoids doing the trick? 2019 Jan 1
24 30609881 Flavonoid Silibinin Increases Hair-Inductive Property Via Akt and Wnt/β-Catenin Signaling Activation in 3-Dimensional-Spheroid Cultured Human Dermal Papilla Cells. 2019 Feb 28 1
25 30841474 Flavonoids for preserving pancreatic beta cell survival and function: A mechanistic review. 2019 Mar 1
26 31438982 Inhibition of COX-2, mPGES-1 and CYP4A by isoliquiritigenin blocks the angiogenic Akt signaling in glioma through ceRNA effect of miR-194-5p and lncRNA NEAT1. 2019 Aug 22 1
27 31515296 Morin Inhibits Proliferation and Induces Apoptosis by Modulating the miR-188-5p/PTEN/AKT Regulatory Pathway in CML Cells. 2019 Dec 1
28 29375715 Dietary flavonoid tangeretin induces reprogramming of epithelial to mesenchymal transition in prostate cancer cells by targeting the PI3K/Akt/mTOR signaling pathway. 2018 Jan 1
29 29861773 The Flavonoid Jaceosidin from Artemisia princeps Induces Apoptotic Cell Death and Inhibits the Akt Pathway in Oral Cancer Cells. 2018 1
30 30035335 Quercetin-3-methyl ether inhibits esophageal carcinogenesis by targeting the AKT/mTOR/p70S6K and MAPK pathways. 2018 Nov 1
31 30050147 Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells. 2018 Jul 26 4
32 30301316 Regulation of AKT Activity by Inhibition of the Pleckstrin Homology Domain-PtdIns(3,4,5)P3 Interaction Using Flavonoids. 2018 Aug 28 4
33 30478366 Total flavonoids from Semen Cuscutae target MMP9 and promote invasion of EVT cells via Notch/AKT/MAPK signaling pathways. 2018 Nov 26 1
34 26592500 Antitumor effects of deguelin on H460 human lung cancer cells in vitro and in vivo: Roles of apoptotic cell death and H460 tumor xenografts model. 2017 Jan 1
35 28336971 Targeting to the non-genomic activity of retinoic acid receptor-gamma by acacetin in hepatocellular carcinoma. 2017 Mar 23 1
36 28364599 Flavonoids from Enicostema littorale blume enhances glucose uptake of cells in insulin resistant human liver cancer (HepG2) cell line via IRS-1/PI3K/Akt pathway. 2017 Jun 1
37 28641164 Protective effects of flavonoids against Alzheimer's disease-related neural dysfunctions. 2017 Sep 1
38 28698611 Flavonoid Enhances the Glyoxalase Pathway in Cerebellar Neurons to Retain Cellular Functions. 2017 Jul 11 1
39 28892039 Metabolites of flavonoid compounds preserve indices of endothelial cell nitric oxide bioavailability under glucotoxic conditions. 2017 Sep 11 1
40 28927111 Luteolin reduces migration of human glioblastoma cell lines via inhibition of the p-IGF-1R/PI3K/AKT/mTOR signaling pathway. 2017 Sep 1
41 27221774 Flavonoid myricetin inhibits TNF-α-stimulated production of inflammatory mediators by suppressing the Akt, mTOR and NF-κB pathways in human keratinocytes. 2016 Aug 5 1
42 27569589 The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-κB signaling. 2016 Oct 1 1
43 29023018 Akt Signal Transduction Pathways and Nuclear Factor-kappa B (NF-κB) Transcription as a Molecular Target of Oral Tongue Squamous Cell Carcinoma (SP-C1) Using Papua's Anthill Plant ( Myrmecodia pendans ). 2016 2
44 25845666 The flavonoid nobiletin inhibits tumor growth and angiogenesis of ovarian cancers via the Akt pathway. 2015 1
45 25892959 Modulation of glucose transporter protein by dietary flavonoids in type 2 diabetes mellitus. 2015 1
46 26089934 The Flavonoid Apigenin Ameliorates Cisplatin-Induced Nephrotoxicity through Reduction of p53 Activation and Promotion of PI3K/Akt Pathway in Human Renal Proximal Tubular Epithelial Cells. 2015 1
47 26439681 Flavonoids of Korean Citrus aurantium L. Induce Apoptosis via Intrinsic Pathway in Human Hepatoblastoma HepG2 Cells. 2015 Dec 1
48 24569980 Myricetin blocks lipoteichoic acid-induced COX-2 expression in human gingival fibroblasts. 2014 Mar 1
49 24623967 Effects of the vegetable polyphenols epigallocatechin-3-gallate, luteolin, apigenin, myricetin, quercetin, and cyanidin in primary cultures of human retinal pigment epithelial cells. 2014 1
50 24901042 Modulation of nitric oxide by flavonoids. 2014 Aug 1