Tretinoin

AKT serine/threonine kinase 1 ; Homo sapiens







60 Article(s)
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1 35278669 ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury. 2022 May 1
2 33074481 Salt-inducible kinase inhibition sensitizes human acute myeloid leukemia cells to all-trans retinoic acid-induced differentiation. 2021 Feb 1
3 34355652 Trametinib enhances ATRA-induced differentiation in AML cells. 2021 Dec 2
4 34579932 Expression of concern: "Tyrosine phosphatase inhibitors combined with retinoic acid can enhance differentiation of neuroblastoma cells and trigger ERK- and AKT-dependent, p53-independent senescence" Cancer Letters, Volume 328, Issue 1, 1 January 2013, Pages 44-54. 2021 Nov 28 1
5 32424865 Rapid human-derived iPSC osteogenesis combined with three-dimensionally printed Ti6Al4V scaffolds for the repair of bone defects. 2020 Dec 1
6 32630207 All-Trans Retinoic Acid Enhances both the Signaling for Priming and the Glycolysis for Activation of NLRP3 Inflammasome in Human Macrophage. 2020 Jul 1 1
7 33276438 Oxidative Stress Impact on the Transcriptome of Differentiating Neuroblastoma Cells: Implication for Psychiatric Disorders. 2020 Dec 2 1
8 30536958 PML/RARA inhibits expression of HSP90 and its target AKT. 2019 Mar 6
9 31322252 All‑trans‑retinoic acid modulates TGF‑β‑induced apoptosis, proliferation, migration and extracellular matrix synthesis of conjunctival fibroblasts by inhibiting PI3K/AKT signaling. 2019 Sep 3
10 31500289 Inhibition of Rho GTPases in Invertebrate Growth Cones Induces a Switch in Responsiveness to Retinoic Acid. 2019 Sep 7 2
11 29305588 Short-term retinoic acid treatment sustains pluripotency and suppresses differentiation of human induced pluripotent stem cells. 2018 Jan 5 1
12 30359286 The deubiquitinating enzyme UCHL1 is a favorable prognostic marker in neuroblastoma as it promotes neuronal differentiation. 2018 Oct 25 1
13 28379293 Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation and differentiation in the mouse†. 2017 Apr 1 1
14 28656276 Lentivirus‑mediated RIG‑I knockdown relieves cell proliferation inhibition, cell cycle arrest and apoptosis in ATRA‑induced NB4 cells via the AKT‑FOXO3A signaling pathway in vitro. 2017 Sep 2
15 26541884 NRF2 Mediates Neuroblastoma Proliferation and Resistance to Retinoic Acid Cytotoxicity in a Model of In Vitro Neuronal Differentiation. 2016 Nov 1
16 26747727 All-trans retinoic acid modulates Wnt3A-induced osteogenic differentiation of mesenchymal stem cells via activating the PI3K/AKT/GSK3β signalling pathway. 2016 Feb 15 1
17 27919568 All-trans retinoic acid suppresses the adhering ability of ARPE-19 cells via mitogen-activated protein kinase and focal adhesion kinase. 2016 Dec 1
18 26257239 Sorafenib enriches epithelial cell adhesion molecule-positive tumor initiating cells and exacerbates a subtype of hepatocellular carcinoma through TSC2-AKT cascade. 2015 Dec 1
19 26295826 Ouabain-Induced Signaling and Cell Survival in SK-N-SH Neuroblastoma Cells Differentiated by Retinoic Acid. 2015 1
20 24300824 All-trans retinoic acid modulates bone morphogenic protein 9-induced osteogenesis and adipogenesis of preadipocytes through BMP/Smad and Wnt/β-catenin signaling pathways. 2014 Feb 2
21 24406248 Reactive oxygen species-regulated glycogen synthase kinase-3β activation contributes to all-trans retinoic acid-induced apoptosis in granulocyte-differentiated HL60 cells. 2014 Mar 1 1
22 24522204 Prohibitin 2 represents a novel nuclear AKT substrate during all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia cells. 2014 May 8
23 24791595 The effect to IL-3Ralpha, downstream PI3k/Akt signaling of all-trans retinoic acid and arsenic trioxide in NB4 cells. 2014 Apr 1
24 24954410 Pulmonary administration of integrin-nanoparticles regenerates collapsed alveoli. 2014 Aug 10 1
25 25118897 Neuroprotective properties of ciliary neurotrophic factor on retinoic acid (RA)-predifferentiated SH-SY5Y neuroblastoma cells. 2014 1
26 25531381 [The anti-apoptotic effect of cytoplasmic alpha-fetoprotein in hepatoma cells induced by all-trans retinoic acid involves activation of the PI3K/AKT signaling pathway]. 2014 Nov 2
27 23022267 Tyrosine phosphatase inhibitors combined with retinoic acid can enhance differentiation of neuroblastoma cells and trigger ERK- and AKT-dependent, p53-independent senescence. 2013 Jan 1 1
28 23142153 Retinoic acid protects against proteasome inhibition associated cell death in SH-SY5Y cells via the AKT pathway. 2013 Jan 4
29 23319320 All-trans retinoic acid displays multiple effects on the growth, lipogenesis and adipokine gene expression of AML-I preadipocyte cell line. 2013 Jan 2
30 23693014 Activation of Akt pathway by transcription-independent mechanisms of retinoic acid promotes survival and invasion in lung cancer cells. 2013 May 21 11
31 23849428 Calcium prevents retinoic acid-induced disruption of the spectrin-based cytoskeleton in keratinocytes through the Src/PI3K-p85α/AKT/PKCδ/β-adducin pathways. 2013 Sep 4
32 23998581 [Effect of curcumin combined with ATRA on differentiation of ATRA-resistant acute promyelocytic leukemia cells]. 2013 Aug 1
33 24030392 A proline-rich loop mediates specific functions of human sialidase NEU4 in SK-N-BE neuronal differentiation. 2013 Dec 3
34 22229477 Combination of valproic acid and ATRA restores RARβ2 expression and induces differentiation in cervical cancer through the PI3K/Akt pathway. 2012 Mar 1
35 22391160 [Regulation of all-trans retinoic acid and arsenic trioxide on CD44v6 expression in NB4 cells]. 2012 Feb 3
36 22766505 PI3K/AKT and ERK regulate retinoic acid-induced neuroblastoma cellular differentiation. 2012 Aug 3 1
37 21354561 All-trans-retinoic acid mediates changes in PI3K and retinoic acid signaling proteins of leiomyomas. 2011 May 5
38 20225234 Differential antiapoptotic effect of erythropoietin on undifferentiated and retinoic acid-differentiated SH-SY5Y cells. 2010 May 1
39 21086135 Akt and PKC are involved not only in upregulation of telomerase activity but also in cell differentiation-related function via mTORC2 in leukemia cells. 2010 Dec 1
40 19056420 Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research. 2009 Jan 2
41 19726747 Retinoic acid-induced nNOS expression depends on a novel PI3K/Akt/DAX1 pathway in human TGW-nu-I neuroblastoma cells. 2009 Nov 2
42 18491231 Death-associated protein 5 (DAP5/p97/NAT1) contributes to retinoic acid-induced granulocytic differentiation and arsenic trioxide-induced apoptosis in acute promyelocytic leukemia. 2008 Jul 3
43 17293044 Resistance to geldanamycin-induced apoptosis in differentiated neuroblastoma SH-SY5Y cells. 2007 Mar 6 1
44 17449938 Promotive effect of minoxidil combined with all-trans retinoic acid (tretinoin) on human hair growth in vitro. 2007 Apr 2
45 17616812 Combination of all-trans retinoic acid and interferon-gamma suppressed PI3K/Akt survival pathway in glioblastoma T98G cells whereas NF-kappaB survival signaling in glioblastoma U87MG cells for induction of apoptosis. 2007 Dec 2
46 16274701 Casein kinase Iepsilon down-regulates phospho-Akt via PTEN, following genotoxic stress-induced apoptosis in hematopoietic cells. 2006 Feb 28 1
47 16304046 FLT3-ITD-, but not BCR/ABL-transformed cells require concurrent Akt/mTor blockage to undergo apoptosis after histone deacetylase inhibitor treatment. 2006 Mar 1 1
48 16456186 Retinoic acid inhibits airway smooth muscle cell migration. 2006 Jun 2
49 16617325 The role of the nuclear Akt activation and Akt inhibitors in all-trans-retinoic acid-differentiated HL-60 cells. 2006 Jun 7
50 16043647 Upregulation of nitric oxide production in vascular endothelial cells by all-trans retinoic acid through the phosphoinositide 3-kinase/Akt pathway. 2005 Aug 2 2