| 1 |
35291604 | PI3K Inhibition Sensitize the Cisplatin-resistant Human Ovarian Cancer Cell OVCAR3 by Induction of Oxidative Stress. | 2022 Jan |
2 |
| 2 |
33450879 | Lysine Deprivation Induces AKT-AADAT Signaling and Overcomes EGFR-TKIs Resistance in EGFR-Mutant Non-Small Cell Lung Cancer Cells. | 2021 Jan 13 |
3 |
| 3 |
33596421 | An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors. | 2021 Feb 16 |
1 |
| 4 |
33723214 | CircRNA circ_0124554 blocked the ubiquitination of AKT promoting the skip lymphovascular invasion on hepatic metastasis in colorectal cancer. | 2021 Mar 15 |
1 |
| 5 |
33755722 | Nuclear DEK preserves hematopoietic stem cells potential via NCoR1/HDAC3-Akt1/2-mTOR axis. | 2021 May 3 |
1 |
| 6 |
33978549 | Targeting EZH2-mediated methylation of histone 3 inhibits proliferation of pediatric acute monocytic leukemia cells in vitro. | 2021 Apr 3 |
1 |
| 7 |
34419497 | miR-26a enhances colorectal cancer cell growth by targeting RREB1 deacetylation to activate AKT-mediated glycolysis. | 2021 Aug 19 |
1 |
| 8 |
34783291 | Knockdown of lysine (K)-specific demethylase 2B KDM2B inhibits glycolysis and induces autophagy in lung squamous cell carcinoma cells by regulating the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway. | 2021 Dec |
1 |
| 9 |
34862383 | Amino acid deprivation induces AKT activation by inducing GCN2/ATF4/REDD1 axis. | 2021 Dec 3 |
1 |
| 10 |
35070988 | Inositol Polyphosphate 4-Phosphatase Type II Is a Tumor Suppressor in Multiple Myeloma. | 2021 |
1 |
| 11 |
32879443 | Aberrant JmjC domain-containing protein 8 (JMJD8) expression promotes activation of AKT and tumor epithelial-mesenchymal transition. | 2020 Oct |
1 |
| 12 |
33123537 | Effect of AKT1 (p. E17K) Hotspot Mutation on Malignant Tumorigenesis and Prognosis. | 2020 |
1 |
| 13 |
31050579 | Fine-tuning AKT kinase activity through direct lysine methylation. | 2019 May |
1 |
| 14 |
31328874 | Signal Transduction in Diffuse Intrinsic Pontine Glioma. | 2019 Nov |
1 |
| 15 |
29523594 | Dual inhibition of AKT-mTOR and AR signaling by targeting HDAC3 in PTEN- or SPOP-mutated prostate cancer. | 2018 Apr |
4 |
| 16 |
28406396 | SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation. | 2017 Apr 13 |
1 |
| 17 |
28539967 | 5,7-Dihydroxyflavone Analogues May Regulate Lipopolysaccharide-Induced Inflammatory Responses by Suppressing IκBα-Linked Akt and ERK5 Phosphorylation in RAW 264.7 Macrophages. | 2017 |
2 |
| 18 |
28628306 | Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells. | 2017 Aug 18 |
2 |
| 19 |
28671020 | The Wnt/β-catenin and PI3K/Akt signaling pathways promote EMT in gastric cancer by epigenetic regulation via H3 lysine 27 acetylation. | 2017 Jul |
1 |
| 20 |
29021135 | Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding. | 2017 Nov 15 |
1 |
| 21 |
26879868 | Ghrelin induces colon cancer cell proliferation through the GHS-R, Ras, PI3K, Akt, and mTOR signaling pathways. | 2016 Apr 5 |
1 |
| 22 |
27070556 | Formation of Peptide Bound Pyrraline in the Maillard Model Systems with Different Lys-Containing Dipeptides and Tripeptides. | 2016 Apr 7 |
1 |
| 23 |
27626683 | SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1. | 2016 Nov 15 |
9 |
| 24 |
25755737 | Vaspin alleviates dysfunction of endothelial progenitor cells induced by high glucose via PI3K/Akt/eNOS pathway. | 2015 |
1 |
| 25 |
25797242 | The promotion of angiogenesis induced by three-dimensional porous beta-tricalcium phosphate scaffold with different interconnection sizes via activation of PI3K/Akt pathways. | 2015 Mar 23 |
1 |
| 26 |
25925379 | Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN. | 2015 Apr |
1 |
| 27 |
24532005 | Lysine suppresses protein degradation through autophagic-lysosomal system in C2C12 myotubes. | 2014 Jun |
1 |
| 28 |
25122478 | Epidermal growth factor stimulates nuclear factor-κB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells. | 2014 |
1 |
| 29 |
25309720 | Posttranslational regulation of Akt in human cancer. | 2014 |
1 |
| 30 |
23300338 | The Akt DUBbed InAktive. | 2013 Jan 8 |
1 |
| 31 |
23434580 | Akt kinase targets the association of CBP with histone H3 to regulate the acetylation of lysine K18. | 2013 Apr 2 |
1 |
| 32 |
23884910 | Akt SUMOylation regulates cell proliferation and tumorigenesis. | 2013 Sep 15 |
2 |
| 33 |
24013425 | Modification of Akt by SUMO conjugation regulates alternative splicing and cell cycle. | 2013 Oct 1 |
1 |
| 34 |
22505016 | Differential effects of AKT1(p.E17K) expression on human mammary luminal epithelial and myoepithelial cells. | 2012 Aug |
1 |
| 35 |
21321111 | mTOR complex 2 targets Akt for proteasomal degradation via phosphorylation at the hydrophobic motif. | 2011 Apr 22 |
2 |
| 36 |
20177150 | Activation of AMP-activated protein kinase stimulates the nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in human diploid fibroblasts. | 2010 Apr 30 |
1 |
| 37 |
20403980 | Selective blockade of protein kinase B protects the rat and human myocardium against ischaemic injury. | 2010 Jun 15 |
1 |
| 38 |
20678559 | The role of cyclooxygenase-2-dependent signaling via cyclic AMP response element activation on aromatase up-regulation by o,p'-DDT in human breast cancer cells. | 2010 Oct 20 |
1 |
| 39 |
19351806 | Visfatin activates eNOS via Akt and MAP kinases and improves endothelial cell function and angiogenesis in vitro and in vivo: translational implications for atherosclerosis. | 2009 Jun |
2 |
| 40 |
19713527 | The E3 ligase TRAF6 regulates Akt ubiquitination and activation. | 2009 Aug 28 |
2 |
| 41 |
18791070 | The human ERG1 channel polymorphism, K897T, creates a phosphorylation site that inhibits channel activity. | 2008 Sep 23 |
1 |
| 42 |
17917251 | LIF- and IL-6-induced acetylation of STAT3 at Lys-685 through PI3K/Akt activation. | 2007 Oct |
3 |
| 43 |
16148030 | Thrombin induces expression of FGF-2 via activation of PI3K-Akt-Fra-1 signaling axis leading to DNA synthesis and motility in vascular smooth muscle cells. | 2006 Jan |
1 |
| 44 |
16619521 | The antiproliferative effect of Quercetin in cancer cells is mediated via inhibition of the PI3K-Akt/PKB pathway. | 2006 Mar-Apr |
2 |
| 45 |
16926151 | Suberoylanilide hydroxamic acid induces Akt-mediated phosphorylation of p300, which promotes acetylation and transcriptional activation of RelA/p65. | 2006 Oct 20 |
2 |
| 46 |
15850772 | Inhibition of the PI3K pathway sensitizes fludarabine-induced apoptosis in human leukemic cells through an inactivation of MAPK-dependent pathway. | 2005 Jun 3 |
1 |
| 47 |
16224021 | Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3. | 2005 Oct 14 |
2 |
| 48 |
15100319 | Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils. | 2004 May 1 |
1 |