Tyrosine

c-abl oncogene 1, non-receptor tyrosine kinase ; Mus musculus







57 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33549745 c-Abl activates RIPK3 signaling in Gaucher disease. 2021 May 1 2
2 32291831 Nilotinib Fails to Prevent Synucleinopathy and Cell Loss in a Mouse Model of Multiple System Atrophy. 2020 Jul 2
3 30629551 c-Abl regulates YAPY357 phosphorylation to activate endothelial atherogenic responses to disturbed flow. 2019 Mar 1 1
4 31681772 A cAbl-MRTF-A Feedback Loop Contributes to Hepatic Stellate Cell Activation. 2019 2
5 28819285 Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis. 2018 Mar 2
6 29304860 Role and regulation of Abelson tyrosine kinase in Crk-associated substrate/profilin-1 interaction and airway smooth muscle contraction. 2018 Jan 5 1
7 30236924 Interaction of Abl Tyrosine Kinases with SOCS3 Impairs Its Suppressor Function in Tumorigenesis. 2018 Nov 3
8 25893286 Tyr99 phosphorylation determines the regulatory milieu of tumor suppressor p73. 2016 Jan 28 1
9 25363403 G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis. 2015 Jul 1
10 25432929 Promotion of colorectal cancer invasion and metastasis through activation of NOTCH-DAB1-ABL-RHOGEF protein TRIO. 2015 Feb 1
11 24872081 Involvement of miR-196a in HIV-associated neurocognitive disorders. 2014 Aug 2
12 25219501 c-Abl stabilizes HDAC2 levels by tyrosine phosphorylation repressing neuronal gene expression in Alzheimer's disease. 2014 Oct 2 1
13 23955590 Loss of the xeroderma pigmentosum group B protein binding site impairs p210 BCR/ABL1 leukemogenic activity. 2013 Aug 16 1
14 22787435 A requirement for SOCS-1 and SOCS-3 phosphorylation in Bcr-Abl-induced tumorigenesis. 2012 Jun 9
15 20883783 Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons. 2011 Jan 1
16 21212806 An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis. 2011 Feb 1
17 21368377 Neuronal c-Abl overexpression leads to neuronal loss and neuroinflammation in the mouse forebrain. 2011 1
18 21690296 c-Abl-mediated tyrosine phosphorylation of the T-bet DNA-binding domain regulates CD4+ T-cell differentiation and allergic lung inflammation. 2011 Aug 3
19 19903482 c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration. 2010 Jan 4 2
20 19228876 c-Abl-deficient mice exhibit reduced numbers of peritoneal B-1 cells and defects in BCR-induced B cell activation. 2009 Apr 2
21 19560455 Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa; its implications during capacitation. 2009 Sep 1 1
22 19783996 Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death. 2009 Oct 1
23 18305217 The c-Abl tyrosine kinase regulates actin remodeling at the immune synapse. 2008 Jul 1 1
24 18387943 Phorbol 12-myristate 13-acetate-dependent protein kinase C delta-Tyr311 phosphorylation in cardiomyocyte caveolae. 2008 Jun 27 1
25 16291652 Mutational analysis of the SH2-kinase linker region of Bruton's tyrosine kinase defines alternative modes of regulation for cytoplasmic tyrosine kinase families. 2006 Jan 1
26 16901904 The tyrosine kinase c-Abl protects c-Jun from ubiquitination-mediated degradation in T cells. 2006 Oct 6 1
27 15657136 Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation. 2005 Jan 25 6
28 16151024 cAbl tyrosine kinase mediates reactive oxygen species- and caveolin-dependent AT1 receptor signaling in vascular smooth muscle: role in vascular hypertrophy. 2005 Oct 14 2
29 15268851 Requirement for Abl kinases in T cell receptor signaling. 2004 Jul 27 2
30 12543778 Bcr and Abl interaction: oncogenic activation of c-Abl by sequestering Bcr. 2003 Jan 15 2
31 12543790 SKI-606, a 4-anilino-3-quinolinecarbonitrile dual inhibitor of Src and Abl kinases, is a potent antiproliferative agent against chronic myelogenous leukemia cells in culture and causes regression of K562 xenografts in nude mice. 2003 Jan 15 1
32 12796783 Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction. 2003 Jul 2
33 12921535 Fyn is required for oxidative- and hyperosmotic-stress-induced tyrosine phosphorylation of caveolin-1. 2003 Nov 15 1
34 11857085 Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells. 2002 Feb 21 1
35 12082638 BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl. 2002 May 9 1
36 12107171 Interaction between UV-damaged DNA binding activity proteins and the c-Abl tyrosine kinase. 2002 Sep 20 2
37 11154271 The NH(2)-terminal coiled-coil domain and tyrosine 177 play important roles in induction of a myeloproliferative disease in mice by Bcr-Abl. 2001 Feb 1
38 11390389 c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1. 2001 Aug 3 5
39 11466610 Role for c-Abl and p73 in the radiation response of male germ cells. 2001 Jul 19 1
40 11587359 Phosphatidyl inositol signaling by BCR/ABL: opportunities for drug development. 2001 Aug 1
41 11719217 Activated c-Abl is degraded by the ubiquitin-dependent proteasome pathway. 2001 Nov 13 1
42 10962572 Progressive changes in the leukemogenic signaling in BCR/ABL-transformed cells. 2000 Aug 24 1
43 10964922 c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines. 2000 Nov 10 12
44 8981370 Growth and differentiation signals regulated by the M-CSF receptor. 1997 Jan 1
45 9009273 Mouse disabled (mDab1): a Src binding protein implicated in neuronal development. 1997 Jan 2 1
46 9053848 Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site. 1997 Feb 6 2
47 9228069 Tyrosine phosphorylation of RNA polymerase II carboxyl-terminal domain by the Abl-related gene product. 1997 Jul 25 4
48 9334312 The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity. 1997 Oct 1 1
49 9405482 BCR/ABL-induced leukemogenesis causes phosphorylation of Hef1 and its association with Crkl. 1997 Dec 19 2
50 8702653 An activating mutation in the ATP binding site of the ABL kinase domain. 1996 Aug 9 2