Nitrogen

cytochrome P450 family 2 subfamily C member 8 ; Homo sapiens







15 Article(s)
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1 30205091 Methadone Metabolism and Drug-Drug Interactions: In Vitro and In Vivo Literature Review. 2018 Dec 1
2 26161459 Impact of CYP2C8*3 polymorphism on in vitro metabolism of imatinib to N-desmethyl imatinib. 2016 1
3 24910237 Application of a higher throughput approach to derive apparent Michaelis-Menten constants of isoform-selective p450-mediated biotransformation reactions in human hepatocytes. 2014 1
4 23555822 Metabolism of BYZX in human liver microsomes and cytosol: identification of the metabolites and metabolic pathways of BYZX. 2013 1
5 20977456 Participation of CYP2C8 and CYP3A4 in the N-demethylation of imatinib in human hepatic microsomes. 2010 Nov 1
6 17537870 Hepatic metabolism of MK-0457, a potent aurora kinase inhibitor: interspecies comparison and role of human cytochrome P450 and flavin-containing monooxygenase. 2007 Sep 1
7 15365656 Identification of cytochrome P450 isoforms involved in the metabolism of loperamide in human liver microsomes. 2004 Oct 2
8 12936704 Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N-demethylation in human liver microsomes. 2003 Aug 1
9 11805197 Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate. 2002 Feb 1
10 11606127 Synthesis of sulfaphenazole derivatives and their use as inhibitors and tools for comparing the active sites of human liver cytochromes P450 of the 2C subfamily. 2001 Oct 25 1
11 10771285 Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism. 2000 Apr 14 1
12 10784435 Inhibition of drug-metabolizing enzyme activity in human hepatic cytochrome P450s by bisphenol A. 2000 Apr 1
13 10199594 Contribution of human hepatic cytochrome P450s and steroidogenic CYP17 to the N-demethylation of aminopyrine. 1999 Feb 1
14 10460803 Multiple cytochrome P-450s involved in the metabolism of terbinafine suggest a limited potential for drug-drug interactions. 1999 Sep 2
15 10510156 Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone. 1999 Sep 1