Troglitazone

cytochrome P450 family 2 subfamily C member 8 ; Homo sapiens







10 Article(s)
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1 21178300 Drug-induced idiosyncratic hepatotoxicity: prevention strategy developed after the troglitazone case. 2011 1
2 21511944 In vitro investigation of the glutathione transferase M1 and T1 null genotypes as risk factors for troglitazone-induced liver injury. 2011 Jul 2
3 20214592 Human CYP2C8: structure, substrate specificity, inhibitor selectivity, inducers and polymorphisms. 2009 Nov 1
4 18413310 Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid. 2008 Jun 20 1
5 17201456 Pharmacokinetic interactions with thiazolidinediones. 2007 1
6 16372821 Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance. 2005 1
7 12642470 Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition. 2003 Apr 1
8 11921435 Differentiating members of the thiazolidinedione class: a focus on safety. 2002 Mar-Apr 2
9 10659951 In vitro inhibitory effects of troglitazone and its metabolites on drug oxidation activities of human cytochrome P450 enzymes: comparison with pioglitazone and rosiglitazone. 2000 Jan 2
10 10534310 Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes. 1999 Nov 2