| 1 |
28395199 | Design, synthesis, and biological evaluation of NAD(P)H: Quinone oxidoreductase (NQO1)-targeted oridonin prodrugs possessing indolequinone moiety for hypoxia-selective activation. | 2017 May 26 |
1 |
| 2 |
24666648 | Bexarotene prodrugs: targeting through cleavage by NQO1 (DT-diaphorase). | 2014 Apr 15 |
1 |
| 3 |
25281270 | Synthesis and in vitro evaluation of radioiodinated indolequinones targeting NAD(P)H: quinone oxidoreductase 1 for internal radiation therapy. | 2014 Nov 1 |
2 |
| 4 |
20433816 | ES936 stimulates DNA synthesis in HeLa cells independently on NAD(P)H:quinone oxidoreductase 1 inhibition, through a mechanism involving p38 MAPK. | 2010 Jul 30 |
2 |
| 5 |
17455910 | Development of indolequinone mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1): NQO1 inhibition and growth inhibitory activity in human pancreatic MIA PaCa-2 cancer cells. | 2007 May 22 |
11 |
| 6 |
17571194 | Indolequinone antitumour agents: correlation between quinone structure and rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase. | 2007 May 21 |
3 |
| 7 |
17944451 | Synthesis and evaluation of 3-aryloxymethyl-1,2-dimethylindole-4,7-diones as mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1) activity. | 2007 Nov 15 |
2 |
| 8 |
14505799 | 3-substituted-5-aziridinyl-1-methylindole-4,7-diones as NQO1-directed antitumour agents: mechanism of activation and cytotoxicity in vitro. | 2003 Oct 1 |
2 |
| 9 |
11735396 | Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches. | 2001 Dec 18 |
1 |
| 10 |
10910079 | Increased tumor necrosis factor-alpha sensitivity of MCF-7 cells transfected with NAD(P)H:quinone reductase. | 2000 Jul 1 |
2 |
| 11 |
11040064 | Establishment of an isogenic human colon tumor model for NQO1 gene expression: application to investigate the role of DT-diaphorase in bioreductive drug activation in vitro and in vivo. | 2000 Nov |
1 |
| 12 |
10514277 | Bioreductive activation of a series of indolequinones by human DT-diaphorase: structure-activity relationships. | 1999 Oct 7 |
1 |
| 13 |
9871615 | Indolequinone antitumor agents: relationship between quinone structure and rate of metabolism by recombinant human NQO1. | 1998 Mar 3 |
1 |
| 14 |
7547240 | DT-diaphorase activity in normal and neoplastic human tissues; an indicator for sensitivity to bioreductive agents? | 1995 Oct |
1 |
| 15 |
7514407 | Chemosensitivity to the indoloquinone EO9 is correlated with DT-diaphorase activity and its gene expression. | 1994 Apr 20 |
1 |
| 16 |
7526885 | DT-diaphorase protects cells from the hypoxic cytotoxicity of indoloquinone EO9. | 1994 Dec |
1 |
| 17 |
8262670 | Unusually marked hypoxic sensitization to indoloquinone EO9 and mitomycin C in a human colon-tumour cell line that lacks DT-diaphorase activity. | 1994 Jan 2 |
1 |
| 18 |
1544832 | Structure-activity relationships for DT-diaphorase reduction of hypoxic cell directed agents: indoloquinones and diaziridinyl benzoquinones. | 1992 |
1 |
| 19 |
1714284 | The role of NAD(P)H: quinone reductase (EC 1.6.99.2, DT-diaphorase) in the reductive bioactivation of the novel indoloquinone antitumor agent EO9. | 1991 Jul |
1 |