| 1 |
33360352 | A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation. | 2021 Feb |
2 |
| 2 |
33600944 | A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis. | 2021 Apr |
1 |
| 3 |
33774477 | The diverse functionality of NQO1 and its roles in redox control. | 2021 May |
1 |
| 4 |
34091287 | Transforming iodoquinol into broad spectrum anti-tumor leads: Repurposing to modulate redox homeostasis. | 2021 Aug |
1 |
| 5 |
34234670 | NQO1 Binds and Supports SIRT1 Function. | 2021 |
2 |
| 6 |
34439319 | Measuring NQO1 Bioactivation Using [2H7]Glucose. | 2021 Aug 19 |
1 |
| 7 |
34769515 | Modulation of Cellular NAD+ Attenuates Cancer-Associated Hypercoagulability and Thrombosis via the Inhibition of Tissue Factor and Formation of Neutrophil Extracellular Traps. | 2021 Nov 8 |
4 |
| 8 |
31775023 | The ying and yang of idebenone: Not too little, not too much - cell death in NQO1 deficient cells and the mouse retina. | 2020 May 20 |
2 |
| 9 |
32645959 | Insights into the New Cancer Therapy through Redox Homeostasis and Metabolic Shifts. | 2020 Jul 7 |
2 |
| 10 |
32974194 | Targeting Base Excision Repair in Cancer: NQO1-Bioactivatable Drugs Improve Tumor Selectivity and Reduce Treatment Toxicity Through Radiosensitization of Human Cancer. | 2020 |
2 |
| 11 |
33005608 | Covalent-Assembly Based Fluorescent Probes for Detection of hNQO1 and Imaging in Living Cells. | 2020 |
1 |
| 12 |
30828537 | A pH/ROS Cascade-Responsive Charge-Reversal Nanosystem with Self-Amplified Drug Release for Synergistic Oxidation-Chemotherapy. | 2019 Feb 20 |
2 |
| 13 |
31287140 | Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress. | 2019 Jul 9 |
2 |
| 14 |
31589435 | Enzyme-Instructed Activation of Pro-protein Therapeutics In Vivo. | 2019 Nov 13 |
2 |
| 15 |
32055310 | Engineering an NIR rhodol derivative with spirocyclic ring-opening activation for high-contrast photoacoustic imaging. | 2019 Oct 28 |
2 |
| 16 |
29298345 | Redox modulation of NQO1. | 2018 |
2 |
| 17 |
30026729 | KL1333, a Novel NAD+ Modulator, Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts. | 2018 |
4 |
| 18 |
30114477 | NQO1 regulates mitotic progression and response to mitotic stress through modulating SIRT2 activity. | 2018 Oct |
1 |
| 19 |
27913299 | The inhibitory effect of beta-lapachone on RANKL-induced osteoclastogenesis. | 2017 Jan 22 |
5 |
| 20 |
28592850 | NAD+ augmentation ameliorates acute pancreatitis through regulation of inflammasome signalling. | 2017 Jun 7 |
1 |
| 21 |
28883796 | Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch. | 2017 |
1 |
| 22 |
28916726 | The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism. | 2017 Nov 3 |
2 |
| 23 |
28977855 | Characteristics of ovarian cancer detection by a near-infrared fluorescent probe activated by human NAD(P)H: quinone oxidoreductase isozyme 1 (hNQO1). | 2017 Sep 22 |
2 |
| 24 |
26341473 | Dunnione ameliorates cisplatin ototoxicity through modulation of NAD(+) metabolism. | 2016 Mar |
1 |
| 25 |
27135737 | Cancer Targeted Enzymatic Theranostic Prodrug: Precise Diagnosis and Chemotherapy. | 2016 May 18 |
2 |
| 26 |
27558805 | NAD(P)H-dependent quinone oxidoreductase 1 (NQO1) and cytochrome P450 oxidoreductase (CYP450OR) differentially regulate menadione-mediated alterations in redox status, survival and metabolism in pancreatic β-cells. | 2016 Nov 16 |
2 |
| 27 |
27566573 | De-novo NAD+ synthesis regulates SIRT1-FOXO1 apoptotic pathway in response to NQO1 substrates in lung cancer cells. | 2016 Sep 20 |
3 |
| 28 |
27608947 | NAMPT inhibition synergizes with NQO1-targeting agents in inducing apoptotic cell death in non-small cell lung cancer cells. | 2016 Aug |
1 |
| 29 |
25590809 | NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone. | 2015 Jan 15 |
3 |
| 30 |
25881497 | Non-classical azoreductase secretion in Clostridium perfringens in response to sulfonated azo dye exposure. | 2015 Aug |
1 |
| 31 |
26498527 | Dunnione ameliorates cisplatin-induced small intestinal damage by modulating NAD(+) metabolism. | 2015 Nov 27 |
3 |
| 32 |
24922076 | Augmentation of NAD(+) by NQO1 attenuates cisplatin-mediated hearing impairment. | 2014 Jun 12 |
2 |
| 33 |
23089953 | Characterization of an efficient catalytic and organic solvent-tolerant azoreductase toward methyl red from Shewanella oneidensis MR-1. | 2013 May |
3 |
| 34 |
23321587 | Construction of an integrated enzyme system consisting azoreductase and glucose 1-dehydrogenase for dye removal. | 2013 Feb |
4 |
| 35 |
23648480 | The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1. | 2013 Jul |
1 |
| 36 |
23803694 | NQO1 prevents radiation-induced aneuploidy by interacting with Aurora-A. | 2013 Nov |
1 |
| 37 |
21487704 | The plasma membrane redox enzyme NQO1 sustains cellular energetics and protects human neuroblastoma cells against metabolic and proteotoxic stress. | 2012 Apr |
5 |
| 38 |
22201895 | Toxicological significance of azo dye metabolism by human intestinal microbiota. | 2012 Jan 1 |
3 |
| 39 |
22359433 | BiodEnz:A database of biodegrading enzymes. | 2012 |
1 |
| 40 |
22532167 | An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis. | 2012 Jun 15 |
1 |
| 41 |
23086932 | NAD(P)H:quinone oxidoreductase 1 (NQO1) competes with 20S proteasome for binding with C/EBPα leading to its stabilization and protection against radiation-induced myeloproliferative disease. | 2012 Dec 7 |
2 |
| 42 |
21354327 | In vitro genotoxicity of danthron and its potential mechanism. | 2011 May 18 |
1 |
| 43 |
21502369 | Activation of NAD(P)H:quinone oxidoreductase ameliorates spontaneous hypertension in an animal model via modulation of eNOS activity. | 2011 Aug 1 |
5 |
| 44 |
18848878 | Preferential utilization of NADPH as the endogenous electron donor for NAD(P)H:quinone oxidoreductase 1 (NQO1) in intact pulmonary arterial endothelial cells. | 2009 Jan 1 |
3 |
| 45 |
17396564 | [Energotropic, antihypoxic, and antioxidative effects of flavonoids]. | 2007 |
2 |
| 46 |
17405841 | The expression of NAD(P)H:quinone oxidoreductase 1 is high in human adipose tissue, reduced by weight loss, and correlates with adiposity, insulin sensitivity, and markers of liver dysfunction. | 2007 Jun |
1 |
| 47 |
17455910 | Development of indolequinone mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1): NQO1 inhibition and growth inhibitory activity in human pancreatic MIA PaCa-2 cancer cells. | 2007 May 22 |
1 |
| 48 |
17893042 | Evidence from ESI-MS for NQO1-catalyzed reduction of estrogen ortho-quinones. | 2007 Nov 1 |
1 |
| 49 |
16385446 | A testing framework for identifying susceptibility genes in the presence of epistasis. | 2006 Jan |
1 |
| 50 |
15694256 | No associations between Parkinson's disease and polymorphisms of the quinone oxidoreductase (NQO1, NQO2) genes. | 2005 Mar 3 |
1 |