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serine hydroxymethyltransferase 1 ; Homo sapiens







44 Article(s)
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1 35402174 Serine hydroxymethyltransferase 2 predicts unfavorable outcomes in multiple cancer: a systematic review and meta-analysis. 2022 Mar 2
2 34136101 Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments. 2021 2
3 31967407 Deciphering tissue-based proteome signatures revealed novel subtyping and prognostic markers for thymic epithelial tumors. 2020 Apr 1
4 32142918 Drosha-independent miR-6778-5p strengthens gastric cancer stem cell stemness via regulation of cytosolic one-carbon folate metabolism. 2020 May 28 1
5 33243973 Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity. 2020 Nov 26 1
6 30809670 The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism. 2019 May 7 2
7 30867454 The 5-formyltetrahydrofolate futile cycle reduces pathway stochasticity in an extended hybrid-stochastic model of folate-mediated one-carbon metabolism. 2019 Mar 13 2
8 31127856 Structural basis of inhibition of the human serine hydroxymethyltransferase SHMT2 by antifolate drugs. 2019 Jul 2
9 31581160 High Expression of Serine Hydroxymethyltransferase 2 Indicates Poor Prognosis of Gastric Cancer Patients. 2019 Oct 3 2
10 29339156 Structure and function of cytoplasmic serine hydroxymethyltransferase from Pichia pastoris. 2018 Feb 5 1
11 29627528 The association between donor genetic variations in one-carbon metabolism pathway genes and hepatitis B recurrence after liver transplantation. 2018 Jul 15 1
12 29991441 Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes. 2018 Sep 1 4
13 28265077 Arsenic trioxide targets MTHFD1 and SUMO-dependent nuclear de novo thymidylate biosynthesis. 2017 Mar 21 1
14 28411382 Interaction between Maternal and Paternal SHMT1 C1420T Predisposes to Neural Tube Defects in the Fetus: Evidence from Case-Control and Family-Based Triad Approaches. 2017 Apr 14 2
15 28461497 Folate rescues vitamin B12 depletion-induced inhibition of nuclear thymidylate biosynthesis and genome instability. 2017 May 16 1
16 28762673 Interaction between Maternal and Paternal SHMT1 C1420T Predisposes to Neural Tube Defects in the Fetus: Evidence from Case-Control and Family-Based Triad Approaches. 2017 Jul 17 2
17 29073064 Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. 2017 Oct 24 3
18 29321350 Neuro-fuzzy model of homocysteine metabolism. 2017 Dec 1
19 26717037 A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells. 2016 Jan 26 2
20 27386562 Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. 2016 Jun 1
21 25677305 Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase. 2015 Mar 2
22 26666829 SHMT1 C1420T polymorphism contributes to the risk of non-Hodgkin lymphoma: evidence from 7309 patients. 2015 Dec 14 2
23 24789272 Polymorphism of cytosolic serine hydroxymethyltransferase and breast cancer risk: evidence from a meta-analysis. 2014 Aug 2
24 25194438 Association between cytosolic serine hydroxymethyltransferase (SHMT1) gene polymorphism and cancer risk: a meta-analysis. 2014 Jul 1
25 21178087 Polymorphisms in serine hydroxymethyltransferase 1 and methylenetetrahydrofolate reductase interact to increase cardiovascular disease risk in humans. 2011 Feb 1
26 19707223 No association between cSHMT genotypes and the risk of breast cancer in the Nurses' Health Study. 2010 Jan 2
27 19158217 Moderate dietary vitamin B-6 restriction raises plasma glycine and cystathionine concentrations while minimally affecting the rates of glycine turnover and glycine cleavage in healthy men and women. 2009 Mar 1
28 17446168 Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway. 2007 Jun 15 2
29 17482557 Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells. 2007 Jun 1 2
30 18029478 Glycine turnover and decarboxylation rate quantified in healthy men and women using primed, constant infusions of [1,2-(13)C2]glycine and [(2)H3]leucine. 2007 Dec 2
31 18067453 Small ubiquitin-like modifier-1 (SUMO-1) modification of thymidylate synthase and dihydrofolate reductase. 2007 2
32 16536979 [Correlations between serine hydroxymethyltransferase1 C1420T polymorphisms and susceptibilities to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma]. 2006 Mar 2
33 16830093 Lateral transfers of serine hydroxymethyltransferase (glyA) and UDP-N-acetylglucosamine enolpyruvyl transferase (murA) genes from free-living Actinobacteria to the parasitic chlamydiae. 2006 Aug 1
34 15531579 Mimosine attenuates serine hydroxymethyltransferase transcription by chelating zinc. Implications for inhibition of DNA replication. 2005 Jan 7 1
35 16006999 Polymorphisms and haplotypes of serine hydroxymethyltransferase and risk of squamous cell carcinoma of the head and neck: a case-control analysis. 2005 Aug 2
36 16137637 Properties of human and rabbit cytosolic serine hydroxymethyltransferase are changed by single nucleotide polymorphic mutations. 2005 Oct 1 2
37 15170323 Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism. 2004 Jun 8 2
38 12138190 A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism. 2002 Aug 1
39 12161434 Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses. 2002 Oct 11 2
40 11305908 Lack of catalytic activity of a murine mRNA cytoplasmic serine hydroxymethyltransferase splice variant: evidence against alternative splicing as a regulatory mechanism. 2001 Apr 24 1
41 11516159 The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by (13)C NMR. 2001 Sep 1 2
42 11902725 Alterations in the flow of one-carbon units affect KinB-dependent sporulation in Bacillus subtilis. 1997 Jul 1
43 8786078 Characterisation of a human serine hydroxymethyltransferase pseudogene and its localisation to 1p32.3-33. 1996 Mar 2
44 1532227 Characterization of the formate (for) locus, which encodes the cytosolic serine hydroxymethyltransferase of Neurospora crassa. 1992 Apr 1