Bile Acids and Salts

nuclear receptor subfamily 0 group B member 2 ; Homo sapiens







64 Article(s)
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Pub. Year
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1 35156505 The effectiveness of small heterodimer partner and FGF 19 levels in prediction of perinatal morbidity in intrahepatic cholestasis of pregnancy. 2022 Feb 14 4
2 32598580 The small heterodimer partner inhibits activation of hepatic stellate cells via autophagy. 2020 Jun 2
3 33692750 Chenodeoxycholic Acid Modulates Bile Acid Synthesis Independent of Fibroblast Growth Factor 19 in Primary Human Hepatocytes. 2020 1
4 30419252 Adaptive homeostasis of the vitamin D-vitamin D nuclear receptor axis in 8-methoxypsoralen-induced hepatotoxicity. 2019 Jan 1 1
5 30745141 FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis. 2019 Feb 25 2
6 31628911 Association between the perturbation of bile acid homeostasis and valproic acid-induced hepatotoxicity. 2019 Dec 1
7 31767173 Steroidogenic control of liver metabolism through a nuclear receptor-network. 2019 Dec 1
8 31905685 Gene Expression Profiling of Different Huh7 Variants Reveals Novel Hepatitis C Virus Host Factors. 2019 Dec 28 1
9 29849798 Activation of FXR promotes intestinal metaplasia of gastric cells via SHP-dependent upregulation of the expression of CDX2. 2018 May 1
10 27770549 Long noncoding RNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate shp mRNA decay. 2017 Feb 1
11 28805978 Obeticholic acid, a selective farnesoid X receptor agonist, regulates bile acid homeostasis in sandwich-cultured human hepatocytes. 2017 Aug 1
12 28873070 Functional assessment of genetic variants located in the promoter of SHP1 (NR0B2). 2017 Nov 1
13 26521940 Hypoxic repression of CYP7A1 through a HIF-1α- and SHP-independent mechanism. 2016 Mar 2
14 26609171 Inactivation of Adenomatous Polyposis Coli Reduces Bile Acid/Farnesoid X Receptor Expression through Fxr gene CpG Methylation in Mouse Colon Tumors and Human Colon Cancer Cells. 2016 Feb 1
15 26504773 New Insights into Orphan Nuclear Receptor SHP in Liver Cancer. 2015 1
16 24338587 SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling. 2014 May 1
17 24379397 Structural insights into gene repression by the orphan nuclear receptor SHP. 2014 Jan 14 2
18 24415870 Bile acid increases expression of the histamine-producing enzyme, histidine decarboxylase, in gastric cells. 2014 Jan 7 2
19 24819989 Bile acids are nutrient signaling hormones. 2014 Aug 2
20 24999016 Altered FXR signalling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease. 2014 Nov 1
21 25100060 Another Shp on the horizon for bile acids. 2014 Aug 5 1
22 23299969 Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis. 2013 Apr 1
23 23824184 Bile acid signal-induced phosphorylation of small heterodimer partner by protein kinase Cζ is critical for epigenomic regulation of liver metabolic genes. 2013 Aug 9 9
24 22291651 Rifampicin Does not Significantly Affect the Expression of Small Heterodimer Partner in Primary Human Hepatocytes. 2012 1
25 22577560 A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways. 2012 1
26 23038264 Nuclear receptors HNF4α and LRH-1 cooperate in regulating Cyp7a1 in vivo. 2012 Nov 30 1
27 20970497 Role of nuclear receptor SHP in metabolism and cancer. 2011 Aug 1
28 21262773 Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner. 2011 Apr 3
29 21566081 Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes. 2011 Jul 3
30 21679700 Bile acid signaling after an oral glucose tolerance test. 2011 Sep 1
31 22235657 [Mechanisms of bile acid biosynthesis regulation--autoregulation by bile acids]. 2011 1
32 24212613 Nuclear receptor small heterodimer partner in apoptosis signaling and liver cancer. 2011 Jan 5 1
33 20233723 Regulation of bile acid synthesis by fat-soluble vitamins A and D. 2010 May 7 1
34 20375098 Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation. 2010 Aug 3
35 20444884 Farnesoid X receptor activation mediates head-to-tail chromatin looping in the Nr0b2 gene encoding small heterodimer partner. 2010 Jul 1
36 19185005 High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis. 2009 Apr 2
37 19426389 Bile acids and insulin resistance: implications for treating nonalcoholic fatty liver disease. 2009 May 1
38 19805516 Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis. 2009 Dec 6
39 18307978 Bile acid regulates c-Jun expression through the orphan nuclear receptor SHP induction in gastric cells. 2008 May 2 3
40 18775915 Bile acid induces expression of COX-2 through the homeodomain transcription factor CDX1 and orphan nuclear receptor SHP in human gastric cancer cells. 2008 Dec 4
41 17145766 Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism. 2007 Feb 4
42 17601490 Transcriptional activation of SHP by PPAR-gamma in liver. 2007 Aug 24 1
43 17895379 Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis. 2007 Oct 2 1
44 16436500 The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4alpha. 2006 May 3
45 15796896 Feedback regulation of bile acid synthesis in human liver: importance of HNF-4alpha for regulation of CYP7A1. 2005 May 6 2
46 16168958 Bile acids reduce SR-BI expression in hepatocytes by a pathway involving FXR/RXR, SHP, and LRH-1. 2005 Nov 4 3
47 14672953 Inhibitory effect of the small heterodimer partner on hepatocyte nuclear factor-4 mediates bile acid-induced repression of the human angiotensinogen gene. 2004 Feb 27 2
48 14699511 Enterohepatic bile salt transporters in normal physiology and liver disease. 2004 Jan 2
49 15047713 Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and Foxo1. 2004 May 28 3
50 15123650 Differential regulation of human and mouse orphan nuclear receptor small heterodimer partner promoter by sterol regulatory element binding protein-1. 2004 Jul 2 1