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protein phosphatase 2 phosphatase activator ; Homo sapiens







169 Article(s)
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1 34686773 PP2A-B55: substrates and regulators in the control of cellular functions. 2022 Jan 1
2 34902541 Protein phosphatase 2A in the healthy and failing heart: New insights and therapeutic opportunities. 2022 Mar 2
3 34984583 Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A): Could It Be a Promising Biomarker and Therapeutic Target in Parkinson's Disease? 2022 Feb 1
4 35020443 PP2A-dependent TFEB activation is blocked by PIKfyve-induced mTORC1 activity. 2022 Mar 1 4
5 35092492 Combination of dasatinib and okadaic acid induces apoptosis and cell cycle arrest by targeting protein phosphatase PP2A in chronic myeloid leukemia cells. 2022 Jan 29 1
6 35154432 PP2A promotes apoptosis and facilitates docetaxel sensitivity via the PP2A/p-eIF4B/XIAP signaling pathway in prostate cancer. 2022 Mar 1
7 35217176 Exercise decreases PP2A-specific reversible thiol oxidation in human erythrocytes: Implications for redox biomarkers. 2022 Mar 1
8 35502616 Overexpression of cancerous inhibitor ofPP2A (CIP2A) in acute myeloid leukemia. 2022 May 1
9 32950569 AMOTL2 inhibits JUN Thr239 dephosphorylation by binding PPP2R2A to suppress the proliferation in non-small cell lung cancer cells. 2021 Jan 1
10 33137394 CqPP2A inhibits white spot syndrome virus infection by up-regulating antimicrobial substances expression in red claw crayfish Cherax quadricarinatus. 2021 Mar 2
11 33449151 LFA-1 cluster formation in T-cells depends on L-plastin phosphorylation regulated by P90RSK and PP2A. 2021 Apr 1
12 33718377 Critical Functions of PP2A-Like Protein Phosphotases in Regulating Meiotic Progression. 2021 2
13 33762326 The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway. 2021 Apr 15 1
14 33815291 Sphingolipids as a Culprit of Mitochondrial Dysfunction in Insulin Resistance and Type 2 Diabetes. 2021 2
15 33901925 PP1/PP2A phosphatase inhibition-induced metaplasticity in protein synthesis blocker-treated hippocampal slices: LTP and LTD, or There and Back again. 2021 Jun 18 3
16 33913576 PPP2R1B is modulated by ubiquitination and is essential for spermatogenesis. 2021 May 2
17 34205611 Review of PP2A Tumor Biology and Antitumor Effects of PP2A Inhibitor LB100 in the Nervous System. 2021 Jun 21 1
18 34228795 Protein phosphatase 2A - structure, function and role in neurodevelopmental disorders. 2021 Jul 1 1
19 34241636 Protein Phosphatase 2A (PP2A) mutations in brain function, development, and neurologic disease. 2021 Aug 27 1
20 34253596 Protein Phosphatase 2A as a Therapeutic Target in Small Cell Lung Cancer. 2021 Oct 1
21 34422684 PP2A Phosphatase as an Emerging Viral Host Factor. 2021 1
22 34518217 TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation. 2021 Sep 21 1
23 34534457 SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape. 2021 Nov 4 1
24 34661528 PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107. 2021 Oct 18 2
25 34768523 Differential Expression of the Sphingolipid Pathway Is Associated with Sensitivity to the PP2A Activator FTY720 in Colorectal Cancer Cell Lines. 2021 Oct 27 1
26 34898995 Genetic Variant of PP2A Subunit Gene Confers an Increased Risk of Primary Liver Cancer in Chinese. 2021 1
27 34984142 Refractory Epilepsy in a Toddler With PPP2R1A Gene Mutation and Congenital Hydrocephalus. 2021 Nov 1
28 31541192 Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors. 2020 Jan 1
29 31669744 Nuclear import of IER5 is mediated by a classical bipartite nuclear localization signal and is required for HSF1 full activation. 2020 Jan 1 1
30 31765670 Novel PRMT5-mediated arginine methylations of HSP90A are essential for maintenance of HSP90A function in NDRG2low ATL and various cancer cells. 2020 Feb 1
31 31822503 Protein phosphatase 2A activation as a therapeutic strategy for managing MYC-driven cancers. 2020 Jan 17 2
32 32098814 Serine-Arginine Protein Kinase 1 Regulates Ebola Virus Transcription. 2020 Feb 25 1
33 32156701 Reduction of protein phosphatase 2A (PP2A) complexity reveals cellular functions and dephosphorylation motifs of the PP2A/B'δ holoenzyme. 2020 Apr 24 1
34 32166659 Protein Phosphatase 2A as a Drug Target in the Treatment of Cancer and Alzheimer's Disease. 2020 Feb 1
35 32315618 Selective PP2A Enhancement through Biased Heterotrimer Stabilization. 2020 Apr 30 1
36 32359434 Piecing Together a Broken Tumor Suppressor Phosphatase for Cancer Therapy. 2020 Apr 30 1
37 32468417 1H, 13C and 15N NMR chemical shift assignments of cAMP-regulated phosphoprotein-19 and -16 (ARPP-19 and ARPP-16). 2020 Oct 1
38 32582689 Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development. 2020 1
39 32620552 Phosphorylation on Ser-359 of the α2 subunit in GABA type A receptors down-regulates their density at inhibitory synapses. 2020 Aug 28 1
40 32847617 PP2A and tumor radiotherapy. 2020 Aug 26 1
41 33068647 The PP2A subunit PR130 is a key regulator of cell development and oncogenic transformation. 2020 Dec 1
42 33069748 Restoration of PP2A levels in inflamed microglial cells: Important for neuroprotective M2 microglial viability. 2020 Dec 15 1
43 33184242 High-glucose-induced apoptosis, ROS production and pro-inflammatory response in cardiomyocytes is attenuated by metformin treatment via PP2A activation. 2020 1
44 33243860 Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase. 2020 Nov 27 1
45 33255747 The Serine/Threonine Protein Phosphatase 2A (PP2A) Regulates Syk Activity in Human Platelets. 2020 Nov 25 1
46 33266510 PP2A-B55 Holoenzyme Regulation and Cancer. 2020 Nov 22 1
47 33302514 Differences in Toxic Response Induced by Three Variants of the Diarrheic Shellfish Poisoning Phycotoxins in Human Intestinal Epithelial Caco-2 Cells. 2020 Dec 8 1
48 30453012 Neuronal ceroid lipofuscinosis related ER membrane protein CLN8 regulates PP2A activity and ceramide levels. 2019 Feb 1 1
49 30679389 The Antitumor Drug LB-100 Is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Active-Site Catalytic Metals in PPP5C. 2019 Mar 1
50 30797822 Regulation of the phosphoprotein phosphatase 2A system and its modulation during oxidative stress: A potential therapeutic target? 2019 Jun 1