| 1 |
35203270 | MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression. | 2022 Feb 10 |
1 |
| 2 |
33672718 | Molecular Regulation of Canalicular ABC Transporters. | 2021 Feb 20 |
1 |
| 3 |
34022183 | Monomeric bile acids modulate the ATPase activity of detergent-solubilized ABCB4/MDR3. | 2021 |
6 |
| 4 |
34107287 | Evidence for a credit-card-swipe mechanism in the human PC floppase ABCB4. | 2021 Oct 7 |
2 |
| 5 |
34209301 | RAB10 Interacts with ABCB4 and Regulates Its Intracellular Traffic. | 2021 Jun 30 |
4 |
| 6 |
34385322 | Structures of ABCB4 provide insight into phosphatidylcholine translocation. | 2021 Aug 17 |
4 |
| 7 |
31873305 | Structure of the human lipid exporter ABCB4 in a lipid environment. | 2020 Jan |
1 |
| 8 |
32917728 | Stimulation of ABCB4/MDR3 ATPase activity requires an intact phosphatidylcholine lipid. | 2020 Dec |
6 |
| 9 |
33256620 | Case report: progressive familial intrahepatic cholestasis type 3 with compound heterozygous ABCB4 variants diagnosed 15 years after liver transplantation. | 2020 Nov 30 |
2 |
| 10 |
33383947 | Gene Therapy for Progressive Familial Intrahepatic Cholestasis: Current Progress and Future Prospects. | 2020 Dec 29 |
1 |
| 11 |
30222019 | Paucity of Interlobular Bile Ducts in Multidrug-Resistant P-Glycoprotein 3 (MDR3) Deficiency. | 2019 May |
1 |
| 12 |
30730833 | ABCB4/MDR3 in health and disease - at the crossroads of biochemistry and medicine. | 2019 Sep 25 |
3 |
| 13 |
31040306 | Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models. | 2019 Apr 30 |
1 |
| 14 |
31176036 | Enhancing effect of taurohyodeoxycholate on ABCB4-mediated phospholipid efflux. | 2019 Oct |
4 |
| 15 |
31538486 | Familial low phospholipid-associated cholelithiasis resulting from an autosomal dominant ABCB4 mutation. | 2019 Oct |
1 |
| 16 |
31886153 | Expression Analysis of ATP-Binding Cassette Transporters ABCB11 and ABCB4 in Primary Sclerosing Cholangitis and Variety of Pediatric and Adult Cholestatic and Noncholestatic Liver Diseases. | 2019 |
1 |
| 17 |
29635711 | Genetics of gallstone disease. | 2018 Jul |
1 |
| 18 |
30357767 | ABCB4 Gene Aberrations in Human Liver Disease: An Evolving Spectrum. | 2018 Nov |
2 |
| 19 |
28012258 | Functional defect of variants in the adenosine triphosphate-binding sites of ABCB4 and their rescue by the cystic fibrosis transmembrane conductance regulator potentiator, ivacaftor (VX-770). | 2017 Feb |
4 |
| 20 |
28127842 | Hepatocarcinogenesis in multidrug-resistant P-glycoprotein 3 deficiency. | 2017 May |
1 |
| 21 |
28220208 | ABCB4 missense mutations D243A, K435T, G535D, I490T, R545C, and S978P significantly impair the lipid floppase and likely predispose to secondary pathologies in the human population. | 2017 Jul |
1 |
| 22 |
26153658 | Heterozygous ABCB4 mutations in children with cholestatic liver disease. | 2016 Feb |
3 |
| 23 |
26789121 | A PDZ-Like Motif in the Biliary Transporter ABCB4 Interacts with the Scaffold Protein EBP50 and Regulates ABCB4 Cell Surface Expression. | 2016 |
2 |
| 24 |
26900700 | Functional Rescue of Trafficking-Impaired ABCB4 Mutants by Chemical Chaperones. | 2016 |
3 |
| 25 |
27112167 | Role of Multidrug Resistance Protein 3 in Antifungal-Induced Cholestasis. | 2016 Jul |
1 |
| 26 |
27256251 | Functional characterization of ABCB4 mutations found in progressive familial intrahepatic cholestasis type 3. | 2016 Jun 3 |
4 |
| 27 |
24594635 | Functional analysis of ABCB4 mutations relates clinical outcomes of progressive familial intrahepatic cholestasis type 3 to the degree of MDR3 floppase activity. | 2015 Jan |
3 |
| 28 |
24620780 | Pathophysiological analysis of primary biliary cirrhosis focusing on choline/phospholipid metabolism. | 2015 Mar |
2 |
| 29 |
25173835 | Expression of indocyanine green-related transporters in hepatocellular carcinoma. | 2015 Feb |
1 |
| 30 |
25533467 | A mutation within the extended X loop abolished substrate-induced ATPase activity of the human liver ATP-binding cassette (ABC) transporter MDR3. | 2015 Feb 20 |
1 |
| 31 |
25601960 | ABCB4 exports phosphatidylcholine in a sphingomyelin-dependent manner. | 2015 Mar |
4 |
| 32 |
26256905 | Reversal of advanced fibrosis after long-term ursodeoxycholic acid therapy in a patient with residual expression of MDR3. | 2015 Sep-Oct |
3 |
| 33 |
24045840 | Two ABCB4 point mutations of strategic NBD-motifs do not prevent protein targeting to the plasma membrane but promote MDR3 dysfunction. | 2014 May |
2 |
| 34 |
24122873 | Peroxisome proliferator-activated receptor α activates human multidrug resistance transporter 3/ATP-binding cassette protein subfamily B4 transcription and increases rat biliary phosphatidylcholine secretion. | 2014 Mar |
4 |
| 35 |
24723470 | Phosphorylation of ABCB4 impacts its function: insights from disease-causing mutations. | 2014 Aug |
4 |
| 36 |
24806754 | Molecular mechanistic explanation for the spectrum of cholestatic disease caused by the S320F variant of ABCB4. | 2014 May |
1 |
| 37 |
24953525 | ABCB4: Insights from pathobiology into therapy. | 2014 Oct |
4 |
| 38 |
25133187 | Molecular mechanisms for biliary phospholipid and drug efflux mediated by ABCB4 and bile salts. | 2014 |
1 |
| 39 |
25544413 | LPAC syndrome associated with deletion of the full exon 4 in a ABCB4 genetic mutation in a patient with hepatitis C. | 2014 Dec |
2 |
| 40 |
23305784 | ATPase activity of nucleotide binding domains of human MDR3 in the context of MDR1. | 2013 Apr |
2 |
| 41 |
23468132 | Bile salt-stimulated phospholipid efflux mediated by ABCB4 localized in nonraft membranes. | 2013 May |
4 |
| 42 |
23593265 | Detergent screening and purification of the human liver ABC transporters BSEP (ABCB11) and MDR3 (ABCB4) expressed in the yeast Pichia pastoris. | 2013 |
3 |
| 43 |
22859919 | Hepatobiliary transport in health and disease. | 2012 Apr |
1 |
| 44 |
23141892 | Low phospholipid-associated cholestasis and cholelithiasis. | 2012 Sep |
3 |
| 45 |
21638239 | Cholestatic liver diseases from child to adult: the diversity of MDR3 disease. | 2011 Jun |
2 |
| 46 |
21801087 | Targeting the ABCB4 gene to control cholesterol homeostasis. | 2011 Oct |
4 |
| 47 |
20153493 | Canine ABCB4: Tissue expression and cDNA structure. | 2010 Aug |
1 |
| 48 |
20422497 | Genetic determinants of drug-induced cholestasis and intrahepatic cholestasis of pregnancy. | 2010 May |
3 |
| 49 |
19018976 | ABCB4 sequence variations in young adults with cholesterol gallstone disease. | 2009 May |
1 |
| 50 |
19185004 | A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature. | 2009 Apr |
3 |