Glucose

glucokinase ; Rattus norvegicus







266 Article(s)
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1 33634460 Metformin Attenuates the Metabolic Disturbance and Depression-like Behaviors Induced by Corticosterone and Mediates the Glucose Metabolism Pathway. 2021 May 1
2 32188779 Metabolic control analysis of hepatic glycogen synthesis in vivo. 2020 Apr 7 9
3 32642586 Changes in expression of genes related to glucose metabolism in liver and skeletal muscle of rats exposed to acute hypoxia. 2020 Jul 1
4 33214580 Glucokinase intrinsically regulates glucose sensing and glucagon secretion in pancreatic alpha cells. 2020 Nov 19 6
5 30369030 N-pyridin-2-yl benzamide analogues as allosteric activators of glucokinase: Design, synthesis, in vitro, in silico and in vivo evaluation. 2019 Mar 3
6 30623114 Hyperinsulinemic hypoglycemia subtype glucokinase V91L mutant induces necrosis in β-cells via ATP depletion. 2019 Mar 1
7 29748994 Hypothalamic arcuate nucleus glucokinase regulates insulin secretion and glucose homeostasis. 2018 Sep 4
8 28209058 Rare Sugar Syrup Containing d-Allulose but Not High-Fructose Corn Syrup Maintains Glucose Tolerance and Insulin Sensitivity Partly via Hepatic Glucokinase Translocation in Wistar Rats. 2017 Apr 5 1
9 28539593 Identification of the matricellular protein Fibulin-5 as a target molecule of glucokinase-mediated calcineurin/NFAT signaling in pancreatic islets. 2017 May 24 1
10 28623340 Adenovirus-mediated suppression of hypothalamic glucokinase affects feeding behavior. 2017 Jun 16 1
11 29099131 Alterations in lipid metabolism due to a protein-restricted diet in rats during gestation and/or lactation. 2017 Nov 3 1
12 29167582 Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus. 2017 Nov 22 1
13 26752353 Overexpression of a glucokinase point mutant in the treatment of diabetes mellitus. 2016 Apr 1
14 26997509 Potential role of Hsp90 in rat islet function under the condition of high glucose. 2016 Aug 1
15 27568837 Induction of oxidative stress, suppression of glucose-induced insulin release, ATP production, glucokinase activity, and histomorphometric changes in pancreatic islets of hypothyroid rat. 2016 Nov 15 1
16 25485685 Glucokinase activity in the arcuate nucleus regulates glucose intake. 2015 Jan 9
17 25906449 Role of Islet Glucokinase, Glucose Metabolism, and Insulin Pathway in the Enhancing Effect of Islet Neogenesis-Associated Protein on Glucose-Induced Insulin Secretion. 2015 Aug 1
18 25997216 [Effects of biotin on blood glucose regulation in type 2 diabetes rat model]. 2015 Mar 1
19 26264555 Glucokinase activation is beneficial or toxic to cultured rat pancreatic islets depending on the prevailing glucose concentration. 2015 Oct 1 2
20 24477542 Supraoptic oxytocin and vasopressin neurons function as glucose and metabolic sensors. 2014 Apr 1 1
21 24533087 Characterization of a novel glucokinase activator in rat and mouse models. 2014 3
22 24566088 Glucagon induces translocation of glucokinase from the cytoplasm to the nucleus of hepatocytes by transfer between 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase-2 and the glucokinase regulatory protein. 2014 Jun 1
23 24714398 Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity. 2014 Jun 1 5
24 24731772 Atherogenic, fibrotic and glucose utilising actions of glucokinase activators on vascular endothelium and smooth muscle. 2014 Apr 15 2
25 24739934 Dynamic localization of glucokinase and its regulatory protein in hypothalamic tanycytes. 2014 6
26 24858947 The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats. 2014 4
27 25108335 Regulation of glucokinase activity in liver of hibernating ground squirrel Spermophilus undulatus. 2014 Jul 4
28 23211706 Essential elements for glucosensing by gastric vagal afferents: immunocytochemistry and electrophysiology studies in the rat. 2013 Jan 1
29 23816435 Hepatic glycogen cycling contributes to glucose lowering effects of the glucokinase activator LCZ960. 2013 Sep 5 6
30 24015910 Identification of a new class of glucokinase activators through structure-based design. 2013 Oct 10 2
31 22038520 Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk. 2012 Jan 1
32 22147008 Glucagon-like peptide-1 enhances glucokinase activity in pancreatic β-cells through the association of Epac2 with Rim2 and Rab3A. 2012 Feb 5
33 20817212 Constitutively active heat shock factor 1 enhances glucose-driven insulin secretion. 2011 Jun 1
34 21440571 Glucokinase inhibitor glucosamine stimulates feeding and activates hypothalamic neuropeptide Y and orexin neurons. 2011 Sep 12 2
35 21484215 Glucokinase mediates coupling of glycolysis to mitochondrial metabolism but not to beta cell damage at high glucose exposure levels. 2011 Jul 6
36 21571864 Upregulation of β-cell genes and improved function in rodent islets following chronic glucokinase activation. 2011 Aug 3
37 21664426 The glucokinase activator GKA50 causes an increase in cell volume and activation of volume-regulated anion channels in rat pancreatic β-cells. 2011 Aug 6 1
38 21861178 Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E. 2011 Nov 1
39 20179264 Brain glucosamine boosts protective glucoprivic feeding. 2010 Apr 6
40 20465996 A small-molecule glucokinase activator lowers blood glucose in the sulfonylurea-desensitized rat. 2010 Aug 25 5
41 20566445 Pioglitazone versus metformin in two rat models of glucose intolerance and diabetes. 2010 Jul 1
42 20633633 Gestational 30% and 40% fat diets increase brain GLUT2 and neuropeptide Y immunoreactivity in neonatal Wistar rats. 2010 Nov 1
43 20843823 Quantitative image analysis reveals that phosphorylation of liver-type isozyme of fructose-6-phosphate 2-kinase/fructose-2,6-bisphosphatase does not affect nuclear translocation of glucokinase in rat primary hepatocytes. 2010 Dec 1
44 18612599 Adaptation of glucokinase gene expression in the rat dorsal vagal complex in a model for recurrent intermediate insulin-induced hypoglycemia: impact of gender. 2009 Jan 3
45 18952838 Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes plasma glucose in zucker diabetic fatty rats. 2009 Jan 1
46 19247671 A hepatic protein modulates glucokinase activity in fish and avian liver: a comparative study. 2009 Jul 2
47 19267880 PREB regulates transcription of pancreatic glucokinase in response to glucose and cAMP. 2009 Aug 3
48 19279382 Sex differences in acclimation of hypothalamic arcuate glucokinase gene and protein expression to repeated intermediate insulin administration. 2009 2
49 19641898 Effects of glucokinase activators GKA50 and LY2121260 on proliferation and apoptosis in pancreatic INS-1 beta cells. 2009 Oct 6
50 19744543 In situ coexpression of glucose and monocarboxylate transporter mRNAs in metabolic-sensitive caudal dorsal vagal complex catecholaminergic neurons: transcriptional reactivity to insulin-induced hypoglycemia and caudal hindbrain glucose or lactate repletion during insulin-induced hypoglycemia. 2009 Dec 15 1