Fatty Acids

fatty acid synthase ; Mus musculus







69 Article(s)
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1 33507880 Neonatal hyperoxia inhibits proliferation and survival of atrial cardiomyocytes by suppressing fatty acid synthesis. 2021 Mar 8 1
2 33538705 Effects of ChREBP deficiency on adrenal lipogenesis and steroidogenesis. 2021 Mar 1
3 33870215 Long-term intake of ginger protease-degraded collagen hydrolysate reduces blood lipid levels and adipocyte size in mice. 2021 1
4 33974005 Effects of orlistat combined with enzalutamide and castration through inhibition of fatty acid synthase in a PC3 tumor-bearing mouse model. 2021 May 28 2
5 33989779 Histone H3K9 butyrylation is regulated by dietary fat and stress via an Acyl-CoA dehydrogenase short chain-dependent mechanism. 2021 Nov 1
6 34021470 A lack of ChREBP inhibits mitochondrial cristae formation in brown adipose tissue. 2021 Oct 1
7 34900534 Integrative lipidomic and transcriptomic study unravels the therapeutic effects of saikosaponins A and D on non-alcoholic fatty liver disease. 2021 Nov 1
8 31991181 Role of hepatic neuropeptide Y-Y1 receptors in a methionine-choline-deficient model of non-alcoholic steatohepatitis. 2020 Mar 15 1
9 32169656 Gut microbiota protects from triptolide-induced hepatotoxicity: Key role of propionate and its downstream signalling events. 2020 May 1
10 32850342 Inhibition of Fatty Acid Synthase Upregulates Expression of CD36 to Sustain Proliferation of Colorectal Cancer Cells. 2020 5
11 33054209 FoxO1 Knockdown Promotes Fatty Acid Synthesis via Modulating SREBP1 Activities in the Dairy Goat Mammary Epithelial Cells. 2020 Oct 28 1
12 30779961 Treatment with an inhibitor of fatty acid synthase attenuates bone loss in ovariectomized mice. 2019 May 2
13 31405565 METTL3 inhibits hepatic insulin sensitivity via N6-methyladenosine modification of Fasn mRNA and promoting fatty acid metabolism. 2019 Oct 8 3
14 31527721 Fatty Acid Inhibition Sensitizes Androgen-Dependent and -Independent Prostate Cancer to Radiotherapy via FASN/NF-κB Pathway. 2019 Sep 16 1
15 31921669 Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma. 2019 3
16 28960380 Distinct role of nuclear receptor corepressor 1 regulated de novo fatty acids synthesis in liver regeneration and hepatocarcinogenesis in mice. 2018 Mar 1
17 29149647 Dietary fish oil differentially ameliorates high-fructose diet-induced hepatic steatosis and hyperlipidemia in mice depending on time of feeding. 2018 Feb 1
18 29175182 Impact of diesel exhaust exposure on the liver of mice fed on omega-3 polyunsaturated fatty acids-deficient diet. 2018 Jan 1
19 29475397 Fatty acid synthase is required for profibrotic TGF-β signaling. 2018 Jul 2
20 29569717 The effect of FASN inhibition on the growth and metabolism of a cisplatin-resistant ovarian carcinoma model. 2018 Aug 15 2
21 29572893 Subchronic cadmium exposure upregulates the mRNA level of genes associated to hepatic lipid metabolism in adult female CD1 mice. 2018 Jul 1
22 29684438 The cytoskeleton in 'couch potato-ism': Insights from a murine model of impaired actin dynamics. 2018 Aug 1
23 30618759 Anti-hypercholesterolemic Effects and a Good Safety Profile of SCM-198 in Animals: From ApoE Knockout Mice to Rhesus Monkeys. 2018 2
24 27879277 Eukaryotic translation initiation factor 5A2 promotes metabolic reprogramming in hepatocellular carcinoma cells. 2017 Jan 1
25 27918556 Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model. 2017 Feb 2
26 28223413 Transcriptional activation of lipogenesis by insulin requires phosphorylation of MED17 by CK2. 2017 Feb 21 1
27 28285648 Branched-chain amino acids alleviate hepatic steatosis and liver injury in choline-deficient high-fat diet induced NASH mice. 2017 Apr 1
28 28483667 Effect of brain-derived neurotrophic factor (BDNF) on hepatocyte metabolism. 2017 Jul 3
29 28752043 Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming. 2017 Aug 3
30 29099085 Eburicoic Acid, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects in Palmitate-Treated C2C12 Myotubes and in High-Fat Diet-Fed Mice. 2017 Nov 2 1
31 25979685 Gene expression related to lipid and glucose metabolism in white adipose tissue. 2016 Jan-Feb 1
32 26670611 Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. 2016 Feb 5 1
33 26878389 Diet-induced alteration of fatty acid synthase in prostate cancer progression. 2016 Feb 15 2
34 27277576 Lovastatin, but not orlistat, reduces intestinal polyp volume in an ApcMin/+ mouse model. 2016 Aug 1
35 27806377 Fatty acid synthesis configures the plasma membrane for inflammation in diabetes. 2016 Nov 10 2
36 25574840 UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis. 2015 Feb 1
37 26134042 Antitumor effects of a drug combination targeting glycolysis, glutaminolysis and de novo synthesis of fatty acids. 2015 Sep 1
38 24668799 Fatty acid synthase is required for mammary gland development and milk production during lactation. 2014 May 15 1
39 24771867 Thyroid hormone responsive protein Spot14 enhances catalysis of fatty acid synthase in lactating mammary epithelium. 2014 Jun 2
40 25038053 Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice. 2014 Sep 2
41 25124514 Sub-chronically exposing mice to a polycyclic aromatic hydrocarbon increases lipid accumulation in their livers. 2014 Sep 1
42 22732909 An indoline-derived compound that markedly reduces mouse body weight. 2013 May 1
43 24223732 Fatty acid synthase as a factor required for exercise-induced cognitive enhancement and dentate gyrus cellular proliferation. 2013 2
44 22132320 Cardiomyocyte triglyceride accumulation and reduced ventricular function in mice with obesity reflect increased long chain Fatty Acid uptake and de novo Fatty Acid synthesis. 2012 1
45 22331133 Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter. 2012 Apr 4
46 22449383 Adenosine A₁ receptors do not play a major role in the regulation of lipogenic gene expression in hepatocytes. 2012 May 15 2
47 22877747 Fatty acid synthase inhibitor orlistat induces apoptosis in T cell lymphoma: role of cell survival regulatory molecules. 2012 Nov 2
48 21442130 Overexpression of fatty acid synthase in Middle Eastern epithelial ovarian carcinoma activates AKT and Its inhibition potentiates cisplatin-induced apoptosis. 2011 2
49 21810592 Apolipoprotein E4 exaggerates diabetic dyslipidemia and atherosclerosis in mice lacking the LDL receptor. 2011 Sep 1
50 19156225 Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice. 2009 1