Digoxin

phosphoglycolate phosphatase ; Mus musculus







24 Article(s)
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1 31540689 Estradiol regulation of P-glycoprotein expression in mouse kidney and human tubular epithelial cells, implication for renal clearance of drugs. 2019 Nov 12 1
2 28222448 Acute Effects of Viral Exposure on P-Glycoprotein Function in the Mouse Fetal Blood-Brain Barrier. 2017 1
3 26058994 Drug-Drug Interactions of a Novel κ-Opioid Receptor Agonist, Nalfurafine Hydrochloride, Involving the P-Glycoprotein. 2016 Oct 1
4 27452443 The effect of 17α-ethynylestradiol induced intrahepatic cholestasis of pregnancy on placental P-glycoprotein in mice: Implications in the individualized transplacental digoxin treatment for fetal heart failure. 2016 Aug 2
5 23395915 Effect of repeated dosing on rifampin exposure in BALB/c mice. 2013 Apr 11 2
6 23468867 Effects of sertraline and fluoxetine on p-glycoprotein at barrier sites: in vivo and in vitro approaches. 2013 1
7 23762418 Prenatal endotoxemia and placental drug transport in the mouse: placental size-specific effects. 2013 1
8 23794039 Altered brain uptake of therapeutics in a triple transgenic mouse model of Alzheimer's disease. 2013 Nov 1
9 22266779 Cerebrospinal fluid can be used as a surrogate to assess brain exposures of breast cancer resistance protein and P-glycoprotein substrates. 2012 Apr 3
10 21191377 Rifampin's acute inhibitory and chronic inductive drug interactions: experimental and model-based approaches to drug-drug interaction trial design. 2011 Feb 3
11 21421739 1Alpha,25-dihydroxyvitamin D3 up-regulates P-glycoprotein via the vitamin D receptor and not farnesoid X receptor in both fxr(-/-) and fxr(+/+) mice and increased renal and brain efflux of digoxin in mice in vivo. 2011 Jun 1
12 19833843 Functional characterization of mouse organic anion transporting peptide 1a4 in the uptake and efflux of drugs across the blood-brain barrier. 2010 Jan 1
13 17683917 A review on the impact of P-glycoprotein on the penetration of drugs into the brain. Focus on psychotropic drugs. 2008 Mar 1
14 18812023 Lack of difference in pulmonary absorption of digoxin, a P-glycoprotein substrate, in mdr1a-deficient and mdr1a-competent mice. 2008 Oct 1
15 16306209 Ontogeny of renal P-glycoprotein expression in mice: correlation with digoxin renal clearance. 2005 Dec 5
16 14569074 Effect of interferon-gamma on the pharmacokinetics of digoxin, a P-glycoprotein substrate, intravenously injected into the mouse. 2004 Jan 1
17 14744937 Effect of recombinant interleukin-2 pretreatment on oral and intravenous digoxin pharmacokinetics and P-glycoprotein activity in mice. 2004 Feb 1
18 12950465 Evidence for an active transport of morphine-6-beta-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier. 2003 Sep 2
19 11914641 Recombinant interleukin-2 treatment decreases P-glycoprotein activity and paclitaxel metabolism in mice. 2002 Jan 1
20 11959808 Resolution of P-glycoprotein and non-P-glycoprotein effects on drug permeability using intestinal tissues from mdr1a (-/-) mice. 2002 Apr 1
21 12128165 Altered drug disposition of the platelet activating factor antagonist apafant in mdr1a knockout mice. 2002 Aug 4
22 12130739 Effect of interleukin-2 on intestinal P-glycoprotein expression and functionality in mice. 2002 Aug 2
23 10562306 Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure. 1999 Nov 1
24 8647944 P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. 1996 Jun 1 1