Sorafenib

BCL2 antagonist/killer 1 ; Homo sapiens







12 Article(s)
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Title
Pub. Year
#Total Relationships
1 29959200 Arsenic Trioxide and Sorafenib Induce Synthetic Lethality of FLT3-ITD Acute Myeloid Leukemia Cells. 2018 Sep 1
2 27632413 Sorafenib potentiates ABT-737-induced apoptosis in human oral cancer cells. 2017 Jan 1
3 28154184 Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma. 2017 Apr 21 2
4 25617717 The proteomic 2D-DIGE approach reveals the protein voltage-dependent anion channel 2 as a potential therapeutic target in epithelial thyroid tumours. 2015 Mar 15 1
5 21604268 Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli. 2012 Apr 1
6 22188816 Sorafenib sensitizes (-)-gossypol-induced growth suppression in androgen-independent prostate cancer cells via Mcl-1 inhibition and Bak activation. 2012 Feb 1
7 22446485 Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process. 2012 Jun 21 1
8 22689683 The sorafenib plus nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of FLT3 and p53 status. 2012 Nov 1
9 20197401 Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells. 2010 Mar 1
10 18200035 Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway. 2008 Apr 1
11 18765530 Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. 2008 Sep 1 1
12 17698840 Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization. 2007 Oct 12 1