Paclitaxel

mitogen-activated protein kinase 14 ; Homo sapiens







32 Article(s)
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1 32829374 Octreotide-Paclitaxel Conjugate Reverses Paclitaxel Resistance by p38 Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in A2780/Taxol Human Ovarian Cancer Cells. 2020 Aug 23 3
2 30829071 Plastin 3 down-regulation augments the sensitivity of MDA-MB-231 cells to paclitaxel via the p38 MAPK signalling pathway. 2019 Dec 6
3 30084832 Paclitaxel Sensitivity of Ovarian Cancer Can be Enhanced by Knocking Down Pairs of Kinases that Regulate MAP4 Phosphorylation and Microtubule Stability. 2018 Oct 15 1
4 28117030 Three Combined Treatments, a Novel HDAC Inhibitor OBP-801/YM753, 5-Fluorouracil, and Paclitaxel, Induce G₂ Phase Arrest Through the p38 Pathway in Human Ovarian Cancer Cells. 2017 Sep 21 1
5 26799187 p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells. 2016 Feb 16 8
6 25858687 Lentinan exerts synergistic apoptotic effects with paclitaxel in A549 cells via activating ROS-TXNIP-NLRP3 inflammasome. 2015 Aug 2
7 26503059 IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel. 2015 Oct 27 1
8 24681252 CX3CL1-mediated macrophage activation contributed to paclitaxel-induced DRG neuronal apoptosis and painful peripheral neuropathy. 2014 Aug 1
9 24787013 Reversion of apoptotic resistance of TP53-mutated Burkitt lymphoma B-cells to spindle poisons by exogenous activation of JNK and p38 MAP kinases. 2014 May 1 1
10 23228696 Metformin-mediated downregulation of p38 mitogen-activated protein kinase-dependent excision repair cross-complementing 1 decreases DNA repair capacity and sensitizes human lung cancer cells to paclitaxel. 2013 Feb 15 7
11 21074392 Involvement of oxidative stress in taxol-induced apoptosis in chronic myelogenous leukemia K562 cells. 2012 May 1
12 21968419 c-Jun N-terminal kinase mediates microtubule-depolymerizing agent-induced microtubule depolymerization and G2/M arrest in MCF-7 breast cancer cells. 2012 Jan 1
13 19918793 Taxol induces paraptosis independent of both protein synthesis and MAPK pathway. 2010 Feb 1
14 20624405 Additive effects of C(2)-ceramide on paclitaxel-induced premature senescence of human lung cancer cells. 2010 Sep 11 1
15 19048624 Synergistic anti-tumor effect of paclitaxel with CRM197, an inhibitor of HB-EGF, in ovarian cancer. 2009 Mar 15 3
16 19717209 Potentiation of paclitaxel-induced apoptosis by galectin-13 overexpression via activation of Ask-1-p38-MAP kinase and JNK/SAPK pathways and suppression of Akt and ERK1/2 activation in U-937 human macrophage cells. 2009 Dec 1
17 17987264 Retinoids induced astrocytic differentiation with down regulation of telomerase activity and enhanced sensitivity to taxol for apoptosis in human glioblastoma T98G and U87MG cells. 2008 Mar 1
18 18068334 Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2. 2008 Feb 4
19 18704310 Targeting of p38 mitogen-activated protein kinases to early growth response gene 1 (EGR-1) in the human paclitaxel-resistance ovarian carcinoma cells. 2008 Aug 1
20 17974988 Chemotherapeutic agents up-regulate the cytomegalovirus promoter: implications for bioluminescence imaging of tumor response to therapy. 2007 Nov 1 1
21 18231754 The relationship between p38MAPK and apoptosis during paclitaxel resistance of ovarian cancer cells. 2007 Dec 5
22 16515784 ERK activation by thymosin-beta-4 (TB4) overexpression induces paclitaxel-resistance. 2006 May 15 3
23 15657900 Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity. 2005 May 20 3
24 15700118 Inhibition of HER-2 by three independent targeting strategies increases paclitaxel resistance of SKOV-3 ovarian carcinoma cells. 2005 Feb 1
25 12796407 Paclitaxel induces apoptosis via protein kinase A- and p38 mitogen-activated protein-dependent inhibition of the Na+/H+ exchanger (NHE) NHE isoform 1 in human breast cancer cells. 2003 Jun 3
26 12821934 Role of the p38 MAPK pathway in cisplatin-based therapy. 2003 Jun 26 2
27 12181443 Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific. 2002 Sep 1
28 12516968 Fas-mediated signaling enhances sensitivity of human soft tissue sarcoma cells to anticancer drugs by activation of p38 kinase. 2002 Dec 1
29 11313944 Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53. 2001 Jan 11 3
30 11408609 Sequence-dependent potentiation of paclitaxel-mediated apoptosis in human leukemia cells by inhibitors of the mitogen-activated protein kinase kinase/mitogen-activated protein kinase pathway. 2001 Jul 2
31 11597122 Quercetin abrogates taxol-mediated signaling by inhibiting multiple kinases. 2001 Oct 15 1
32 10623471 Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells. 2000 Jan 10 1