Bortezomib

BH3 interacting domain death agonist ; Homo sapiens







10 Article(s)
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1 29167312 Inhibition of O-GlcNAcase Sensitizes Apoptosis and Reverses Bortezomib Resistance in Mantle Cell Lymphoma through Modification of Truncated Bid. 2018 Feb 1
2 23449448 Phosphorylation of signal transducer and activator of transcription 1 reduces bortezomib-mediated apoptosis in cancer cells. 2013 Feb 28 1
3 22393246 ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines. 2012 Jun 1
4 21459798 Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway. 2011 May 15 3
5 21525171 Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis. 2011 Jun 15 2
6 17898295 The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro. 2007 Oct 1
7 16528474 JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways. 2006 Apr 1
8 15813915 In vitro cytotoxic effect of proteasome inhibitor bortezomib in combination with purine nucleoside analogues on chronic lymphocytic leukaemia cells. 2005 May 1
9 15929791 Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy. 2005 Jun 1 1
10 14513055 The proteasome inhibitor bortezomib promotes mitochondrial injury and apoptosis induced by the small molecule Bcl-2 inhibitor HA14-1 in multiple myeloma cells. 2003 Oct 1