Sorafenib

BH3 interacting domain death agonist ; Homo sapiens







33 Article(s)
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1 29468456 Phase 1, open-label, dose-escalation study of sorafenib in combination with eribulin in patients with advanced, metastatic, or refractory solid tumors. 2018 Apr 1
2 28120036 Phase Ib study of codrituzumab in combination with sorafenib in patients with non-curable advanced hepatocellular carcinoma (HCC). 2017 Feb 1
3 29181069 Sorafenib combined with hepatectomy in patients with intermediate-stage and advanced hepatocellular carcinoma. 2017 Oct 1
4 25332069 Phase II trial evaluating the efficacy of sorafenib (BAY 43-9006) and correlating early fluorodeoxyglucose positron emission tomography-CT response to outcome in patients with recurrent and/or metastatic head and neck cancer. 2016 Mar 1
5 27765348 Ginkgo biloba extract in combination with sorafenib is clinically safe and tolerable in advanced hepatocellular carcinoma patients. 2016 Nov 15 1
6 24346857 Phase II trial of sorafenib in advanced salivary adenoid cystic carcinoma of the head and neck. 2015 Feb 2
7 25043125 Inhibition of myeloid cell leukemia-1: Association with sorafenib-induced apoptosis in human mucoepidermoid carcinoma cells and tumor xenograft. 2015 Sep 4
8 26020033 Phase I trial of sorafenib following liver transplantation in patients with high-risk hepatocellular carcinoma. 2015 Mar 2
9 26097873 Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells. 2015 1
10 24309512 Multi-kinase inhibition in ovarian cancer. 2014 Jan 1
11 24399106 Critical role of sorafenib exposure over time for its antitumor activity in thyroid cancer. 2014 Jun 1
12 24786603 Phase I study of sorafenib combined with radiation therapy and temozolomide as first-line treatment of high-grade glioma. 2014 May 27 1
13 25173458 TACE plus sorafenib for the treatment of hepatocellular carcinoma: results of the multicenter, phase II SOCRATES trial. 2014 Nov 1
14 26158148 Efficacy of Sorafenib for Advanced Hepatocellular Carcinoma and Prognostic Factors. 2014 Jun 1
15 23263993 A phase I study of sorafenib, oxaliplatin and 2 days of high dose capecitabine in advanced pancreatic and biliary tract cancer: a Wisconsin oncology network study. 2013 Aug 2
16 23591401 A randomized phase II trial of maintenance therapy with Sorafenib in front-line ovarian carcinoma. 2013 Jul 1
17 23811306 Early prediction of response to sorafenib in patients with advanced hepatocellular carcinoma: the role of dynamic contrast enhanced ultrasound. 2013 Nov 1
18 23876062 A phase 3 tRial comparing capecitabinE in combination with SorafenIb or pLacebo for treatment of locally advanced or metastatIc HER2-Negative breast CancEr (the RESILIENCE study): study protocol for a randomized controlled trial. 2013 Jul 22 2
19 22678005 Clinical response after sorafenib for hepatocellular carcinoma in elderly patients: a report of two cases. 2012 Mar-Apr 1
20 22767146 Sorafenib in advanced melanoma: a critical role for pharmacokinetics? 2012 Jul 24 1
21 23277740 Efficacy of sorafenib after liver transplantation in patients with primary hepatic carcinoma exceeding the Milan criteria: a preliminary study. 2012 1
22 20521052 A phase I open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer. 2011 Apr 1
23 20593250 Long-term stable disease in metastatic renal cell carcinoma: sorafenib sequenced to sunitinib and everolimus: a case study. 2011 Dec 1
24 20706860 Pharmacokinetic interaction involving sorafenib and the calcium-channel blocker felodipine in a patient with hepatocellular carcinoma. 2011 Dec 2
25 21224376 Evaluation of KRAS mutations, angiogenic biomarkers, and DCE-MRI in patients with advanced non-small-cell lung cancer receiving sorafenib. 2011 Mar 1 1
26 21240686 Sorafenib in unresectable intrahepatic cholangiocellular carcinoma: a case report. 2011 Jan 1
27 21954442 Phase I trial of sorafenib in patients with recurrent or progressive malignant glioma. 2011 Dec 4
28 21036880 Continuous administration of sorafenib in combination with transarterial chemoembolization in patients with hepatocellular carcinoma: results of a phase I study. 2010 4
29 21122388 [Clinical observation of transarterial chemoembolization combined with sorafenib for advanced hepatocellular carcinoma]. 2010 Sep 1
30 21122420 [Therapeutic efficacy and prognostic factors of sorafenib treatment in patients with unresectable primary hepatocellular carcinoma]. 2010 Aug 1
31 19101137 Combination of sorafenib and doxorubicin in patients with advanced hepatocellular carcinoma: results from a phase I extension trial. 2009 Mar 1
32 18477034 Phase I and pharmacokinetic study of sorafenib, an oral multikinase inhibitor, in Japanese patients with advanced refractory solid tumors. 2008 Jul 2
33 18765530 Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. 2008 Sep 1 1