Doxorubicin

tumor necrosis factor ; Rattus norvegicus







87 Article(s)
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1 32106718 Montelukast ameliorates doxorubicin-induced cardiotoxicity via modulation of p-glycoprotein and inhibition of ROS-mediated TNF-α/NF-κB pathways. 2022 Mar 1
2 34635025 Cardioprotective effect of allyl isothiocyanate in a rat model of doxorubicin acute toxicity. 2022 Mar 1
3 34766659 Biochemical and histological alterations of doxorubicin-induced neurotoxicity in rats: Protective role of luteolin. 2022 Mar 1
4 34837640 Curcumin Ameliorates Doxorubicin-Induced Cardiotoxicity and Hepatotoxicity Via Suppressing Oxidative Stress and Modulating iNOS, NF-κB, and TNF-α in Rats. 2022 Feb 2
5 35135461 Pharmacological Study of A3 Adenosine Receptor agonist (AB Meca) in Xenograft Lung Cancer Model in Mice through In Silico and In Vivo Approach: Targeting TNF-α. 2022 1
6 35408518 Cardiorenal Protective Effect of Costunolide against Doxorubicin-Induced Toxicity in Rats by Modulating Oxidative Stress, Inflammation and Apoptosis. 2022 Mar 25 1
7 35523286 Infliximab and/or MESNA alleviate doxorubicin-induced Alzheimer's disease-like pathology in rats: A new insight into TNF-α/Wnt/β-catenin signaling pathway. 2022 Jul 15 1
8 35624893 Anti-Inflammatory, Anti-Apoptotic, and Antioxidant Roles of Honey, Royal Jelly, and Propolis in Suppressing Nephrotoxicity Induced by Doxorubicin in Male Albino Rats. 2022 May 23 1
9 31240966 Protective effects of gallic acid on doxorubicin-induced cardiotoxicity; an experimantal study. 2021 Jun 2
10 32400214 Use of selenium to ameliorate doxorubicin induced hepatotoxicity by targeting pro-inflammatory cytokines. 2021 Jan 1
11 32812453 Evaluation of the protective effect of paricalcitol and vitamin D3 at doxorubicin nephrotoxicity in rats with 99mTechnetium-dimercaptosuccinic acid renal scintigraphy and biochemical methods. 2021 Feb 2
12 33460662 Berberine ameliorates doxorubicin-induced cognitive impairment (chemobrain) in rats. 2021 Mar 15 3
13 33484087 Proanthocyanidin alleviates doxorubicin-induced cardiac injury by inhibiting NF-kB pathway and modulating oxidative stress, cell cycle, and fibrogenesis. 2021 Apr 2
14 33704910 Trimetazidine improved adriamycin-induced cardiomyopathy by downregulating TNF-α, BAX, and VEGF immunoexpression via an antioxidant mechanism. 2021 Jun 1
15 33929391 Ozone Attenuated H9c2 Cell Injury Induced by Doxorubicin. 2021 Jul 1 1
16 34156690 DOX and MET treatment induces cognitive impairment through downregulation of IL-1-alpha and IRS-1 in the rat brain. 2021 Jun 2
17 34170670 Nerolidol, a Sesquiterpene from the Essential Oils of Aromatic Plants, Attenuates Doxorubicin-Induced Chronic Cardiotoxicity in Rats. 2021 Jul 7 1
18 34187945 Protective effects and mechanism of coenzyme Q10 and vitamin C on doxorubicin-induced gastric mucosal injury and effects of intestinal flora. 2021 Jul 1 1
19 34205494 Nerolidol Attenuates Oxidative Stress, Inflammation, and Apoptosis by Modulating Nrf2/MAPK Signaling Pathways in Doxorubicin-Induced Acute Cardiotoxicity in Rats. 2021 Jun 21 1
20 34392583 Thymoquinone has a neuroprotective effect against inflammation, oxidative stress, and endoplasmic reticulum stress in the brain cortex, medulla, and hippocampus due to doxorubicin. 2021 Nov 1
21 34459233 Exosomal Micro-RNA-96 Derived From Bone Marrow Mesenchymal Stem Cells Inhibits Doxorubicin-Induced Myocardial Toxicity by Inhibiting the Rac1/Nuclear Factor-κB Signaling Pathway. 2021 Sep 7 1
22 34494664 Therapeutic effects of thymoquinone in doxorubicin-induced hepatotoxicity via oxidative stress, inflammation and apoptosis. 2021 Nov 1
23 34510376 Dose-Dependent Cardioprotective Effect of Hemin in Doxorubicin-Induced Cardiotoxicity Via Nrf-2/HO-1 and TLR-5/NF-κB/TNF-α Signaling Pathways. 2021 Dec 2
24 34530017 Protective effects of hesperidin through attenuation of Ki67 expression against DMBA-induced breast cancer in female rats. 2021 Nov 15 1
25 30406686 Naringenin prevents doxorubicin-induced toxicity in kidney tissues by regulating the oxidative and inflammatory insult in Wistar rats. 2020 Oct 1
26 32036411 Evaluation of the protective effect of edaravone on doxorubicin nephrotoxicity by [99mTc]DMSA renal scintigraphy and biochemical methods. 2020 Aug 2
27 32086107 P-Coumaric Acid Mitigates Doxorubicin-Induced Nephrotoxicity Through Suppression of Oxidative Stress, Inflammation and Apoptosis. 2020 Jan 3
28 32258120 Sinapic Acid Ameliorates Oxidative Stress, Inflammation, and Apoptosis in Acute Doxorubicin-Induced Cardiotoxicity via the NF-κB-Mediated Pathway. 2020 2
29 32627270 Nimbolide prevents myocardial damage by regulating cardiac biomarkers, antioxidant level, and apoptosis signaling against doxorubicin-induced cardiotoxicity in rats. 2020 Jul 6 2
30 32647085 Effect of meloxicam (cyclooygenase-2 inhibitor) versus vitamin D3 (cholecalciferol) as ameliorating agents of progressive doxorubicin-induced nephrotoxicity in rats. 2020 Jun 30 1
31 32745770 Protective effects of diallyl trisulfide (DATS) against doxorubicin-induced inflammation and oxidative stress in the brain of rats. 2020 Nov 20 2
32 32765656 Catalpol ameliorates doxorubicin-induced inflammation and oxidative stress in H9C2 cells through PPAR-γ activation. 2020 Aug 1
33 32963742 Adrenomedullin protects rat dorsal root ganglion neurons against doxorubicin-induced toxicity by ameliorating oxidative stress. 2020 Sep 1
34 32968640 MiR-181c protects cardiomyocyte injury by preventing cell apoptosis through PI3K/Akt signaling pathway. 2020 Aug 1
35 33011199 Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain in Sprague-Dawley rats: Emphasis on the modulation of oxidative stress and neuroinflammation. 2020 Dec 15 1
36 33155237 Ulinastatin reduces myocardial injury induced by doxorubicin in SD rats. 2020 Oct 1
37 30551518 Effect of gemfibrozil on cardiotoxicity induced by doxorubicin in male experimental rats. 2019 Jan 1
38 30734091 Irbesartan suppresses cardiac toxicity induced by doxorubicin via regulating the p38-MAPK/NF-κB and TGF-β1 pathways. 2019 Jun 2
39 30836069 β-Caryophyllene, a natural bicyclic sesquiterpene attenuates doxorubicin-induced chronic cardiotoxicity via activation of myocardial cannabinoid type-2 (CB2) receptors in rats. 2019 May 1 1
40 30991846 Mesenchymal stem cells pretreated with platelet-rich plasma modulate doxorubicin-induced cardiotoxicity. 2019 Jul 1
41 31115031 Lixisenatide protects doxorubicin-induced renal fibrosis by activating wNF-κB/TNF-α and TGF-β/Smad pathways. 2019 May 3
42 31172809 Embryonic stem cell-derived exosomes inhibit doxorubicin-induced TLR4-NLRP3-mediated cell death-pyroptosis. 2019 Aug 1 1
43 29085977 All-trans-retinoic acid ameliorates doxorubicin-induced cardiotoxicity: in vivo potential involvement of oxidative stress, inflammation, and apoptosis via caspase-3 and p53 down-expression. 2018 Jan 1
44 29321061 Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis. 2018 Jan 10 2
45 29779119 A Chemosensitizer Drug: Disulfiram Prevents Doxorubicin-Induced Cardiac Dysfunction and Oxidative Stress in Rats. 2018 Oct 1
46 30351976 Protective effect of irbesartan against doxorubicin-induced nephrotoxicity in rats: implication of AMPK, PI3K/Akt, and mTOR signaling pathways. 2018 Dec 1
47 27897404 Doxorubicin inhibits muscle inflammation after eccentric exercise. 2017 Apr 1
48 28100487 Doxorubicin-induced nitrosative stress is mitigated by vitamin C via the modulation of nitric oxide synthases. 2017 Apr 1 1
49 28586512 Ellagic acid and rosmarinic acid attenuate doxorubicin-induced testicular injury in rats. 2017 Sep 1
50 28614779 The effect of the nitroxide pirolin on oxidative stress induced by doxorubicin and taxanes in the rat brain. 2017 Apr 1