veliparib

BRCA2 DNA repair associated ; Homo sapiens







9 Article(s)
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1 35435472 A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovarian or triple-negative breast cancer. 2022 May 1
2 32218813 Pharmacological ascorbate induces 'BRCAness' and enhances the effects of Poly(ADP-Ribose) polymerase inhibitors against BRCA1/2 wild-type ovarian cancer. 2020 Apr 1
3 27739325 A randomized Phase II study of veliparib with temozolomide or carboplatin/paclitaxel versus placebo with carboplatin/paclitaxel in BRCA1/2 metastatic breast cancer: design and rationale. 2017 Feb 1
4 28356425 Efficacy of the PARP Inhibitor Veliparib with Carboplatin or as a Single Agent in Patients with Germline BRCA1- or BRCA2-Associated Metastatic Breast Cancer: California Cancer Consortium Trial NCT01149083. 2017 Aug 1 1
5 27488020 Treatment of breast cancer 2 (BRCA2)-mutant follicular dendritic cell sarcoma with a poly ADP-ribose polymerase (PARP) inhibitor: a case report. 2016 Aug 3 1
6 25818403 A phase II evaluation of the potent, highly selective PARP inhibitor veliparib in the treatment of persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer in patients who carry a germline BRCA1 or BRCA2 mutation - An NRG Oncology/Gynecologic Oncology Group study. 2015 Jun 2
7 23474559 BRCA-associated pancreatic cancer: the evolving management. 2013 Mar 10 2
8 22291137 Failure of iniparib to inhibit poly(ADP-Ribose) polymerase in vitro. 2012 Mar 15 1
9 22101337 Poly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent. 2011 Dec 1 1