2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid

BRCA2 DNA repair associated ; Homo sapiens







5 Article(s)
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1 29313279 A phase 1 study of PARP-inhibitor ABT-767 in advanced solid tumors with BRCA1/2 mutations and high-grade serous ovarian, fallopian tube, or primary peritoneal cancer. 2018 Oct 1
2 28247011 Population pharmacokinetics of ABT-767 in BRCA1 or BRCA2 mutation carriers with advanced solid tumors or in subjects with high grade serous ovarian, primary peritoneal or fallopian tube cancer. 2017 Mar 1
3 22778154 Enhancement of synthetic lethality via combinations of ABT-888, a PARP inhibitor, and carboplatin in vitro and in vivo using BRCA1 and BRCA2 isogenic models. 2012 Sep 1
4 22833573 Identification of DNA repair pathways that affect the survival of ovarian cancer cells treated with a poly(ADP-ribose) polymerase inhibitor in a novel drug combination. 2012 Oct 2
5 22101337 Poly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent. 2011 Dec 1 1