Cholesterol

proprotein convertase subtilisin/kexin type 9 ; Homo sapiens







724 Article(s)
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1 34196811 Lipoprotein(a). 2022 1
2 34375677 Efficacy evaluation of PCSK9 monoclonal antibody (Evolocumab) in combination with Rosuvastatin and Ezetimibe on cholesterol levels in patients with coronary heart disease (CHD): A retrospective analysis from a single center in China. 2022 Apr 1
3 34582002 Cost-Effectiveness Analysis of Evolocumab for the Treatment of Dyslipidemia in the Kingdom of Saudi Arabia. 2022 Mar 1
4 34758978 Effect of Loss-of-Function Genetic Variants in PCSK9 on Glycemic Traits, Neurocognitive Impairment, and Hepatobiliary Function. 2022 Jan 1 1
5 34809446 PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Triggers Vascular Smooth Muscle Cell Senescence and Apoptosis: Implication of Its Direct Role in Degenerative Vascular Disease. 2022 Jan 5
6 34907967 Therapeutic application of genome editing in dyslipidemia. 2022 Apr 1 1
7 34922870 Determinants of Plaque Progression Despite Very Low Low-Density Lipoprotein-Cholesterol Levels With the PCSK9 Inhibitor, Evolocumab. 2022 Apr 1
8 35007650 Associations of pro-protein convertase subtilisin-like kexin type 9, soluble low-density lipoprotein receptor and coronary artery disease: A case-control study. 2022 Mar 1 2
9 35048716 Effects of PCSK9 Targeting: Alleviating Oxidation, Inflammation, and Atherosclerosis. 2022 Feb 2
10 35050192 Gene Therapy Targeting PCSK9. 2022 Jan 12 1
11 35052871 Effects of Alirocumab on Triglyceride Metabolism: A Fat-Tolerance Test and Nuclear Magnetic Resonance Spectroscopy Study. 2022 Jan 17 1
12 35159928 The Impact of the COVID-19 Outbreak on Patients' Adherence to PCSK9 Inhibitors Therapy. 2022 Jan 18 1
13 35162992 Emerging Insights on the Diverse Roles of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Chronic Liver Diseases: Cholesterol Metabolism and Beyond. 2022 Jan 19 9
14 35175350 Low-density lipoprotein cholesterol levels exceed the recommended European threshold for PCSK9i initiation: lessons from the HEYMANS study. 2022 Jun 6 1
15 35213538 Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation. 2022 Feb 1
16 35221836 Potential dual inhibitors of PCSK-9 and HMG-R from natural sources in cardiovascular risk management. 2022 2
17 35237909 Metformin enhances LDL-cholesterol uptake by suppressing the expression of the pro-protein convertase subtilisin/kexin type 9 (PCSK9) in liver cells. 2022 Jun 2
18 35246337 Efficacy and Safety of PCSK9 Monoclonal Antibodies in Patients With Diabetes. 2022 Feb 1
19 35252378 Proprotein Convertase Subtilisin/Kexin Type 9 and Inflammation: An Updated Review. 2022 2
20 35263196 The Biological Relevance of PCSK9: When Less Is Better…. 2022 Mar 9 4
21 35294778 Effect of a PCSK9 inhibitor and a statin on cholesterol efflux capacity: A limitation of current cholesterol-lowering treatments? 2022 Jul 1
22 35307759 Antitumor activity and molecular mechanism of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition. 2022 Jun 1
23 35320320 Effect of PCSK9 inhibition with evolocumab on lipoprotein subfractions in familial dysbetalipoproteinemia (type III hyperlipidemia). 2022 4
24 35323658 The Emerging Roles of Intracellular PCSK9 and Their Implications in Endoplasmic Reticulum Stress and Metabolic Diseases. 2022 Feb 26 1
25 35326219 Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Beyond Lipids: The Role in Oxidative Stress and Thrombosis. 2022 Mar 16 2
26 35336039 Computational Design and Biological Evaluation of Analogs of Lupin Peptide P5 Endowed with Dual PCSK9/HMG-CoAR Inhibiting Activity. 2022 Mar 18 2
27 35381104 Latest clinical evidence about the effect of PCSK9 monoclonal antibodies in patients with familial hypercholesterolaemia: an updated meta-analysis. 2022 2
28 35387881 PCSK9 and Cardiovascular Disease in Individuals with Moderately Decreased Kidney Function. 2022 Jun 1
29 35454343 Ramadan Intermittent Fasting Is Associated with Changes in Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Metabolically Healthy Obese Subjects. 2022 Mar 31 2
30 35467263 Resistin Modulates Low-Density Lipoprotein Cholesterol Uptake in Human Placental Explants via PCSK9. 2022 Apr 25 1
31 35494422 The Relationship of Circulating Proprotein Convertase Subtilisin/Kexin Type 9 With TSH and Lipid Profile in Newly Diagnosed Patients With Subclinical and Overt Hypothyroidism. 2022 1
32 35508320 PCSK9 inhibitors and ezetimibe for the reduction of cardiovascular events: a clinical practice guideline with risk-stratified recommendations. 2022 May 4 1
33 35552680 The Multifaceted Biology of PCSK9. 2022 May 12 1
34 35571202 Updated Understanding of the Crosstalk Between Glucose/Insulin and Cholesterol Metabolism. 2022 2
35 35585420 Retinoic acid increases the cellular cholesterol predominantly in a mTOR-independent manner. 2022 May 18 2
36 35599686 Testosterone Deficiency Promotes Hypercholesteremia and Attenuates Cholesterol Liver Uptake via AR/PCSK9/LDLR Pathways. 2022 1
37 35600486 Effect of Alirocumab on Coronary Calcification in Patients With Coronary Artery Disease. 2022 2
38 32090592 Are anti-inflammatory agents and nutraceuticals - novel inhibitors of PCSK9? 2021 3
39 32875580 Physiology and role of PCSK9 in vascular disease: Potential impact of localized PCSK9 in vascular wall. 2021 Apr 1
40 32988222 PCSK9 (Proprotein Convertase Subtilisin/Kexin 9) Enhances Platelet Activation, Thrombosis, and Myocardial Infarct Expansion by Binding to Platelet CD36. 2021 Jan 5 1
41 32991689 PCSK9 and LRP5 in macrophage lipid internalization and inflammation. 2021 Jul 27 2
42 33091218 PCSK9 rs11591147 R46L loss-of-function variant protects against liver damage in individuals with NAFLD. 2021 Feb 2
43 33108009 Effects of proprotein convertase subtilisin/kexin type 9 and nilotinib plasma concentrations on nilotinib-induced hypercholesterolaemia in patients with chronic myeloid leukaemia. 2021 Apr 3
44 33128247 Micro- and macrovascular cardiac allograft vasculopathy in relation to 91 cardiovascular biomarkers in heart transplant recipients-An exploratory study. 2021 Jan 3
45 33177004 In vitro selection generates RNA aptamer that antagonizes PCSK9-LDLR interaction and recovers cellular LDL uptake. 2021 Mar 2
46 33226544 Assessment of Low LDL Cholesterol in Patients Treated by PCSK9 Inhibition: Comparison of Martin/Hopkins and Friedewald Estimations. 2021 Aug 1
47 33236356 PCSK9 and atherosclerosis: Looking beyond LDL regulation. 2021 Apr 3
48 33295631 Proprotein convertase subtilisin/kexin type 9 in the dyslipidaemia of patients with axial spondyloarthritis is related to disease activity. 2021 May 14 2
49 33307067 PCSK9: Associated with cardiac diseases and their risk factors? 2021 Jun 15 2
50 33326580 High-sugar feeding and increasing cholesterol levels in infants. 2021 Mar 21 1