Folic Acid

methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase ; Mus musculus







10 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 29659962 Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects. 2018 Apr 1 2
2 27597531 Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors. 2017 Mar 1
3 28559181 Deletion of one allele of Mthfd1 (methylenetetrahydrofolate dehydrogenase 1) impairs learning in mice. 2017 Aug 14 2
4 27707701 Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development. 2016 Nov 1
5 26408344 MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice. 2015 Dec 1
6 25213861 Nuclear enrichment of folate cofactors and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) protect de novo thymidylate biosynthesis during folate deficiency. 2014 Oct 24 3
7 23190757 Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration. 2013 Jan 4
8 23684804 Dietary and genetic manipulations of folate metabolism differentially affect neocortical functions in mice. 2013 Jul-Aug 1
9 22378735 Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice. 2012 Apr 7
10 19033438 Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. 2009 Jan 16 1