| 1 |
32686977 | An in vitro approach to simulate the process of 5-fluorouracil degradation with dihydropyrimidine dehydrogenase: the process in accordance to the first-order kinetic reaction. | 2021 Jan |
2 |
| 2 |
28927087 | Gimeracil enhances the antitumor effect of cisplatin in oral squamous cell carcinoma cells in vitro and in vivo. | 2017 Sep |
6 |
| 3 |
25169655 | Elevation in 5-FU-induced apoptosis in head and neck cancer stem cells by a combination of CDHP and GSK3β inhibitors. | 2015 Mar |
1 |
| 4 |
26396918 | Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression. | 2015 |
1 |
| 5 |
25360167 | Successful curative resection of gallbladder cancer following S-1 chemotherapy: A case report and review of the literature. | 2014 Dec |
1 |
| 6 |
23420099 | Factors affecting the sensitivity of human-derived esophageal carcinoma cell lines to 5-fluorouracil and cisplatin. | 2013 Feb |
1 |
| 7 |
22510597 | Effects of depletion of dihydropyrimidine dehydrogenase on focus formation and RPA phosphorylation. | 2012 |
2 |
| 8 |
21378348 | A phase I study evaluating the effect of CDHP as a component of S-1 on the pharmacokinetics of 5-fluorouracil. | 2011 Feb |
2 |
| 9 |
21668582 | Gimeracil, an inhibitor of dihydropyrimidine dehydrogenase, inhibits the early step in homologous recombination. | 2011 Sep |
8 |
| 10 |
18172246 | Can inhibiting dihydropyrimidine dehydrogenase limit hand-foot syndrome caused by fluoropyrimidines? | 2008 Jan 1 |
2 |
| 11 |
18309485 | High intratumoral dihydropyrimidine dehydrogenase mRNA levels in pancreatic cancer associated with a high rate of response to S-1. | 2008 Dec |
2 |
| 12 |
18799915 | [Case report of gastric cancer patient who suffered life-threatening adverse events including severe myelosuppression during neoadjuvant chemotherapy with S-1 and CDDP combination]. | 2008 Sep |
2 |
| 13 |
19093184 | Successful treatment of advanced gallbladder cancer with an anticancer drug S-1: assessment based on intratumoral gene. | 2008 Dec |
2 |
| 14 |
17092280 | The significance of the expression of dihydropyrimidine dehydrogenase in prostate cancer. | 2007 Mar |
2 |
| 15 |
17603216 | Development of a pharmacokinetic model to optimize the dosage regimen of TS-1, a combination preparation of tegafur, gimeracil and oteracil potassium. | 2007 Jun |
3 |
| 16 |
17699726 | Alteration of dihydropyrimidine dehydrogenase expression by IFN-alpha affects the antiproliferative effects of 5-fluorouracil in human hepatocellular carcinoma cells. | 2007 Aug |
3 |
| 17 |
17982671 | Epigenetic regulation of chemosensitivity to 5-fluorouracil and cisplatin by zebularine in oral squamous cell carcinoma. | 2007 Dec |
2 |
| 18 |
16897969 | [Pharmacokinetics of S-1]. | 2006 Jun |
2 |
| 19 |
15949589 | Role of dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine against non-small cell lung cancer--in correlation with the tumoral expression of thymidylate synthase and dihydropyrimidine dehydrogenase. | 2005 Jul |
3 |
| 20 |
15993511 | The role of thymidylate synthase and dihydropyrimidine dehydrogenase in resistance to 5-fluorouracil in human lung cancer cells. | 2005 Sep |
3 |
| 21 |
16315929 | [A trial of TS-1 administration on the basis of the pharmacokinetic study for an advanced gastric cancer patient with impaired renal function]. | 2005 Oct |
4 |
| 22 |
12739060 | Pharmacokinetics of S-1, an oral formulation of ftorafur, oxonic acid and 5-chloro-2,4-dihydroxypyridine (molar ratio 1:0.4:1) in patients with solid tumors. | 2003 Jul |
2 |
| 23 |
12751387 | Significance of dihydropyrimidine dehydrogenase activity in renal cell carcinoma. | 2003 Mar |
2 |
| 24 |
12775012 | S-1 in gastric cancer: a comprehensive review. | 2003 |
2 |
| 25 |
14551502 | Dihydropyrimidine dehydrogenase inhibition as a strategy for the oral administration of 5-fluorouracil: utility in the treatment of advanced colorectal cancer. | 2003 Oct |
1 |
| 26 |
12044515 | Enhancement of the antitumour activity of 5-fluorouracil (5-FU) by inhibiting dihydropyrimidine dehydrogenase activity (DPD) using 5-chloro-2,4-dihydroxypyridine (CDHP) in human tumour cells. | 2002 Jun |
11 |
| 27 |
12111108 | Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor agent in animal model and in patients with impaired renal function. | 2002 Jul |
2 |
| 28 |
11290431 | The significance of dihydropyrimidine dehydrogenase (DPD) activity in bladder cancer. | 2001 Mar |
2 |