Oximes

butyrylcholinesterase ; Homo sapiens







79 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35526478 Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents. 2022 Aug 5 5
2 33592259 Reactivation of organophosphate-inhibited serum butyrylcholinesterase by novel substituted phenoxyalkyl pyridinium oximes and traditional oximes. 2021 Mar 30 4
3 33990679 Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase. 2021 May 14 5
4 32086265 Early diagnosis of nerve agent exposure with a mobile test kit and implications for medical countermeasures: a trigger to react. 2020 Apr 3
5 32198755 Diagnostics and treatment of nerve agent poisoning-current status and future developments. 2020 Nov 1
6 32583098 Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers. 2020 Sep 2
7 32639532 Enantioseparation, in vitro testing, and structural characterization of triple-binding reactivators of organophosphate-inhibited cholinesterases. 2020 Aug 14 3
8 32786529 Catalytic Detoxification of Organophosphorus Nerve Agents by Butyrylcholinesterase-Polymer-Oxime Bioscavengers. 2020 Sep 14 2
9 33105595 Benzobicyclo[3.2.1]octene Derivatives as a New Class of Cholinesterase Inhibitors. 2020 Oct 22 1
10 31004594 Butyrylcholinesterase inhibited by nerve agents is efficiently reactivated with chlorinated pyridinium oximes. 2019 Jul 1 1
11 31276662 Reactivation potency of two novel oximes (K456 and K733) against paraoxon-inhibited acetyl and butyrylcholinesterase: In silico and in vitro models. 2019 Sep 1 2
12 29735900 Synthesis, Biological Evaluation, and Docking Studies of Novel Bisquaternary Aldoxime Reactivators on Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon. 2018 May 7 2
13 27125569 Mechanistic studies of new oximes reactivators of human butyryl cholinesterase inhibited by cyclosarin and sarin. 2017 May 4
14 27358236 Pseudocatalytic scavenging of the nerve agent VX with human blood components and the oximes obidoxime and HI-6. 2017 Mar 3
15 28693885 Post-exposure treatment with the oxime RS194B rapidly reverses early and advanced symptoms in macaques exposed to sarin vapor. 2017 Aug 25 2
16 28737687 New Cinchona Oximes Evaluated as Reactivators of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Organophosphorus Compounds. 2017 Jul 22 3
17 26899146 Emergence of catalytic bioscavengers against organophosphorus agents. 2016 Nov 25 1
18 27238725 Design and synthesis of N-substituted-2-hydroxyiminoacetamides and interactions with cholinesterases. 2016 Nov 25 2
19 27654152 A comprehensive evaluation of novel oximes in creation of butyrylcholinesterase-based nerve agent bioscavengers. 2016 Nov 1 5
20 27693733 Pyridoxal oxime derivative potency to reactivate cholinesterases inhibited by organophosphorus compounds. 2016 Nov 16 2
21 28327676 Management of Organophosphorus Poisoning. 2016 Sep 1
22 28959540 The possible role of intravenous lipid emulsion in the treatment of chemical warfare agent poisoning. 2016 1
23 24912784 Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyrylcholinesterase. 2015 Mar 5
24 25450746 Adaptation of a dynamic in vitro model with real-time determination of butyrylcholinesterase activity in the presence of cyclosarin and an oxime. 2015 Feb 1
25 23339663 Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry. 2013 Feb 18 1
26 23461011 [Studying kinetics of oxime-induced reactivation of malathion-inhibited cholinesterase]. 2013 2
27 22160885 Nano-intercalated organophosphorus-hydrolyzing enzymes in organophosphorus antagonism. 2012 Mar 2
28 22703537 Effect of different oximes on rat and human cholinesterases inhibited by methamidophos: a comparative in vitro and in silico study. 2012 Dec 1
29 23115436 Recent advances in the treatment of organophosphorous poisonings. 2012 Jun 1
30 21464125 New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases. 2011 Jun 3 1
31 21673941 In vitro ability of currently available oximes to reactivate organophosphate pesticide-inhibited human acetylcholinesterase and butyrylcholinesterase. 2011 1
32 21983245 Potential of two new oximes in reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by organophosphate compounds: an in vitro study. 2011 Dec 4
33 20004171 Butyrylcholinesterase for protection from organophosphorus poisons: catalytic complexities and hysteretic behavior. 2010 Feb 15 1
34 20206154 Pseudo-catalytic scavenging: searching for a suitable reactivator of phosphorylated butyrylcholinesterase. 2010 Sep 6 5
35 20345348 Interaction of nerve agent antidotes with cholinergic systems. 2010 1
36 20929049 Pharmacological agents in the prophylaxis/treatment of organophosphorous pesticide intoxication. 2010 Jul 2
37 21152278 Reactivation of human acetylcholinesterase and butyrylcholinesterase inhibited by leptophos-oxon with different oxime reactivators in vitro. 2010 Aug 3 2
38 19368529 Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun. 2009 Jun 12 4
39 19428953 Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: a kinetic analysis. 2009 May 17 3
40 19586353 In vitro oxime-assisted reactivation of paraoxon-inhibited human acetylcholinesterase and butyrylcholinesterase. 2009 Jul 1
41 20032868 Novel bisquaternary oximes--reactivation of acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon. 2009 Dec 1 1
42 18344198 In vitro oxime protection of human red blood cell acetylcholinesterase inhibited by diisopropyl-fluorophosphate. 2008 May 1
43 18975951 Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation. 2008 Nov 26 4
44 16904809 Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase. 2007 Apr 20 2
45 17126503 Cholinesterase pseudo-activity, oximolysis, esterolysis, thiocholine ester hydrolysis by oximes: what's in a name? 2007 Jan 10 1
46 17716616 Limitation of the Ellman method: cholinesterase activity measurement in the presence of oximes. 2007 Nov 15 2
47 18220560 Cholinesterase reactivators: the fate and effects in the organism poisoned with organophosphates/nerve agents. 2007 Dec 1
48 16644174 LC-UV and LC-MS evaluation of stress degradation behaviour of avizafone. 2006 Jun 16 1
49 16982122 Pretreatment with pyridinium oximes improves antidotal therapy against tabun poisoning. 2006 Nov 10 4
50 12475193 Review of oximes in the antidotal treatment of poisoning by organophosphorus nerve agents. 2002 1