| 1 |
34218351 | Experimental investigation of a combinational iron chelating protoporphyrin IX prodrug for fluorescence detection and photodynamic therapy. | 2022 Mar |
2 |
| 2 |
35054318 | Recognized and Emerging Features of Erythropoietic and X-Linked Protoporphyria. | 2022 Jan 8 |
3 |
| 3 |
35094360 | Methods to Measure the Inhibition of ABCG2 Transporter and Ferrochelatase Activity to Enhance Aminolevulinic Acid-Protoporphyrin IX Fluorescence-Guided Tumor Detection and Resection. | 2022 |
4 |
| 4 |
35149260 | Analysis of corticosteroid and antiepileptic drug treatment effects on heme biosynthesis mRNA expression in lower-grade gliomas: Potential implications for 5-ALA metabolization. | 2022 Jun |
1 |
| 5 |
35309058 | Microcytosis in Erythropoietic Protoporphyria. | 2022 |
3 |
| 6 |
32909293 | Zinc-protoporphyrin determination by HPLC with fluorescence detection as a biomarker of lead effect in artisanal pottery workers. | 2021 Feb |
1 |
| 7 |
33475175 | Erythropoietic protoporphyria- associated hepatopathy: expanding the spectra of brown pigments encountered in hepatic specimens. | 2021 Jul |
1 |
| 8 |
33756123 | Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria. | 2021 Aug 19 |
1 |
| 9 |
34280433 | The ubiquitous mitochondrial protein unfoldase CLPX regulates erythroid heme synthesis by control of iron utilization and heme synthesis enzyme activation and turnover. | 2021 Aug |
1 |
| 10 |
34402499 | Insight into the function of active site residues in the catalytic mechanism of human ferrochelatase. | 2021 Sep 17 |
1 |
| 11 |
34940556 | Iron, Heme Synthesis and Erythropoietic Porphyrias: A Complex Interplay. | 2021 Nov 23 |
2 |
| 12 |
32313951 | Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of erythropoietic protoporphyria. | 2020 May 21 |
1 |
| 13 |
32755804 | Heme Synthesis Inhibition Blocks Angiogenesis via Mitochondrial Dysfunction. | 2020 Aug 21 |
4 |
| 14 |
33275677 | Updates on the diagnosis and management of the most common hereditary porphyrias: AIP and EPP. | 2020 Dec 4 |
4 |
| 15 |
30517741 | The Isoniazid Metabolites Hydrazine and Pyridoxal Isonicotinoyl Hydrazone Modulate Heme Biosynthesis. | 2019 Mar 1 |
3 |
| 16 |
30660387 | GLRX5 mutations impair heme biosynthetic enzymes ALA synthase 2 and ferrochelatase in Human congenital sideroblastic anemia. | 2019 Nov |
2 |
| 17 |
30704898 | Erythropoietic Protoporphyria and X-Linked Protoporphyria: pathophysiology, genetics, clinical manifestations, and management. | 2019 Nov |
1 |
| 18 |
30765471 | Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis. | 2019 Sep |
2 |
| 19 |
30767226 | Ferrochelatase Deficiency Abrogated the Enhancement of Aminolevulinic Acid-mediated Protoporphyrin IX by Iron Chelator Deferoxamine. | 2019 Jul |
2 |
| 20 |
30938825 | Erythropoietic Protoporphyria in a Japanese Population. | 2019 Jun 1 |
1 |
| 21 |
31076252 | Delta-aminolevulinic acid synthase 2 expression in combination with iron as modifiers of disease severity in erythropoietic protoporphyria. | 2019 Nov |
3 |
| 22 |
31555729 | The essential role of the transporter ABCG2 in the pathophysiology of erythropoietic protoporphyria. | 2019 Sep |
2 |
| 23 |
31602323 | Loss of ferrochelatase is protective against colon cancer cells: ferrochelatase a possible regulator of the long noncoding RNA H19. | 2019 Oct |
2 |
| 24 |
29116687 | Erythropoietic protoporphyria in an adult with sequential liver and hematopoietic stem cell transplantation: A case report. | 2018 Mar |
2 |
| 25 |
29721068 | Enhancement of Cancer-Specific Protoporphyrin IX Fluorescence by Targeting Oncogenic Ras/MEK Pathway. | 2018 |
2 |
| 26 |
29985945 | Inhibition of ferrochelatase impairs vascular eNOS/NO and sGC/cGMP signaling. | 2018 |
4 |
| 27 |
28104494 | Thoughts on interactions between PGRMC1 and diverse attested and potential hydrophobic ligands. | 2017 Jul |
1 |
| 28 |
28149023 | Status of Serum Calcium, Vitamin D and Parathyroid Hormone and Hematological Indices Among Lead Exposed Jewelry Workers in Dhaka, Bangladesh. | 2017 Mar |
2 |
| 29 |
28185024 | Disturbed iron metabolism in erythropoietic protoporphyria and association of GDF15 and gender with disease severity. | 2017 May |
1 |
| 30 |
28553927 | Erythropoietin signaling regulates heme biosynthesis. | 2017 May 29 |
2 |
| 31 |
26588930 | Protoporphyrin IX: the Good, the Bad, and the Ugly. | 2016 Feb |
2 |
| 32 |
26669872 | [Erythropoietic protoporphyria : Clinical manifestations, diagnosis and new therapeutic possibilities]. | 2016 Mar |
1 |
| 33 |
26863403 | Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors. | 2016 May 20 |
3 |
| 34 |
27599036 | A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase. | 2016 Sep 20 |
9 |
| 35 |
27704751 | Identification of FECH gene multiple variations in two Chinese patients with erythropoietic protoporphyria and a review. | 2016 Oct. |
1 |
| 36 |
27801584 | Human Ferrochelatase: Insights for the Mechanism of Ferrous Iron Approaching Protoporphyrin IX by QM/MM and QTCP Free Energy Studies. | 2016 Dec 27 |
1 |
| 37 |
28003770 | Advances in the management of erythropoietic protoporphyria - role of afamelanotide. | 2016 |
1 |
| 38 |
25179834 | In ferrochelatase-deficient protoporphyria patients, ALAS2 expression is enhanced and erythrocytic protoporphyrin concentration correlates with iron availability. | 2015 Jan |
2 |
| 39 |
25414439 | Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites. | 2015 Jan 15 |
1 |
| 40 |
25482442 | Aminolevulinate synthase 2 mediates erythrocyte differentiation by regulating larval globin expression during Xenopus primary hematopoiesis. | 2015 Jan 2 |
1 |
| 41 |
25809721 | Effects of Silencing Heme Biosynthesis Enzymes on 5-Aminolevulinic Acid-mediated Protoporphyrin IX Fluorescence and Photodynamic Therapy. | 2015 Jul-Aug |
1 |
| 42 |
26287972 | Identification of the Mitochondrial Heme Metabolism Complex. | 2015 |
1 |
| 43 |
24864106 | [Heme metabolism as an integral part of iron homeostasis]. | 2014 Jan 2 |
2 |
| 44 |
25278616 | Tracking cancer drugs in living cells by thermal profiling of the proteome. | 2014 Oct 3 |
1 |
| 45 |
22862424 | The p53-dependent expression of frataxin controls 5-aminolevulinic acid-induced accumulation of protoporphyrin IX and photo-damage in cancerous cells. | 2013 Jan-Feb |
1 |
| 46 |
23446439 | Investigation by MD simulation of the key residues related to substrate-binding and heme-release in human ferrochelatase. | 2013 Jun |
1 |
| 47 |
23516484 | Identification of a bacteria-like ferrochelatase in Strongyloides venezuelensis, an animal parasitic nematode. | 2013 |
4 |
| 48 |
23610429 | Interdomain lateral gene transfer of an essential ferrochelatase gene in human parasitic nematodes. | 2013 May 7 |
3 |
| 49 |
24043703 | Salicylic acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity. | 2013 Dec |
1 |
| 50 |
22705251 | A multifunctional 5-aminolevulinic acid derivative induces erythroid differentiation of K562 human erythroleukemic cells. | 2012 Aug 30 |
1 |