Glycine

glycine decarboxylase ; Homo sapiens







44 Article(s)
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1 35460232 Genetic variants in ALDH1L1 and GLDC influence serine to glycine ratio in Hispanic children. 2022 Apr 23 1
2 35508169 Loss of PRMT7 reprograms glycine metabolism to selectively eradicate leukemia stem cells in CML. 2022 Jun 7 1
3 33867731 Evaluation of LKB1 and Serine-Glycine Metabolism Pathway Genes (SHMT1 and GLDC) Expression in AML. 2021 Apr 1
4 33869785 Identification and Characterization of Glycine Decarboxylase as a Direct Target of Snail in the Epithelial-Mesenchymal Transition of Cancer Cells. 2021 Apr 2
5 34244482 mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis. 2021 Jul 9 7
6 34342168 Hormonal regulation of glycine decarboxylase and its relationship to oxidative stress. 2021 Aug 5
7 34513771 Novel GLDC Compound Heterozygous Variant Leading to Nonketotic Hyperglycinemia: Case Report and Literature Review. 2021 2
8 32055850 Glycine by MR spectroscopy is an imaging biomarker of glioma aggressiveness. 2020 Jul 7 2
9 30779965 Glycine decarboxylase regulates the maintenance and induction of pluripotency via metabolic control. 2019 May 1
10 30804330 Glycine decarboxylase induces autophagy and is downregulated by miRNA-30d-5p in hepatocellular carcinoma. 2019 Feb 25 2
11 31279534 Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase Gene. 2019 Oct 1 1
12 31444411 Glycine decarboxylase is a transcriptional target of MYCN required for neuroblastoma cell proliferation and tumorigenicity. 2019 Dec 1
13 31589099 Redox-regulation of mitochondrial metabolism through thioredoxin o1 facilitates light induction of photosynthesis. 2019 1
14 29481666 Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study. 2018 May 1 1
15 29988937 The impact of common genetic variants in the mitochondrial glycine cleavage system on relevant metabolites. 2018 Sep 1
16 30255931 Variants p.Q1236H and p.E1143G in mitochondrial DNA polymerase gamma POLG1 are not associated with increased risk for valproate-induced hepatotoxicity or pancreatic toxicity: A retrospective cohort study of patients with epilepsy. 2018 Nov 1
17 28056489 Use of high-frequency ultrasound to study the prenatal development of cranial neural tube defects and hydrocephalus in Gldc-deficient mice. 2017 Mar 1
18 28325525 Clinical heterogeneity of glycine encephalopathy in three Palestinian siblings: A novel mutation in the glycine decarboxylase (GLDC) gene. 2017 Aug 2
19 28570395 Runs of homozygosity, copy number variation, and risk for depression and suicidal behavior in an Arab Bedouin kindred. 2017 Oct 1
20 29141214 Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure. 2017 Nov 14 2
21 26722042 Epigenetic Silencing of the Putative Tumor Suppressor Gene GLDC (Glycine Dehydrogenase) in Gastric Carcinoma. 2016 Jan 1
22 27481395 Mutation in SLC6A9 encoding a glycine transporter causes a novel form of non-ketotic hyperglycinemia in humans. 2016 Nov 2
23 25855294 SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. 2015 Apr 16 1
24 26067360 Type 2 diabetes alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and recovery. 2015 Aug 1
25 24407464 Diagnosis of glycine encephalopathy in a pediatric patient by detection of a GLDC mutation during initial next generation DNA sequencing. 2014 Mar 2
26 24467211 Glycine decarboxylase is an unusual amino acid decarboxylase involved in tumorigenesis. 2014 Feb 11 7
27 24979213 Differential expression of enzymes associated with serine/glycine metabolism in different breast cancer subtypes. 2014 1
28 25231368 Mutation analysis of glycine decarboxylase, aminomethyltransferase and glycine cleavage system protein-H genes in 13 unrelated families with glycine encephalopathy. 2014 Nov 2
29 22225612 Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis. 2012 Jan 20 2
30 22633639 Two novel missense mutations observed in nonketotic hyperglycinemia. 2012 Jun 1
31 17361008 Genomic deletion within GLDC is a major cause of non-ketotic hyperglycinaemia. 2007 Mar 2
32 16450403 Comprehensive mutation analysis of GLDC, AMT, and GCSH in nonketotic hyperglycinemia. 2006 Apr 1
33 16601880 Genetic heterogeneity of the GLDC gene in 28 unrelated patients with glycine encephalopathy. 2006 Feb 1
34 15670722 Detection of mutations in the glycine decarboxylase gene in patients with nonketotic hyperglycinaemia. 2005 Feb 2
35 15851735 Mild glycine encephalopathy (NKH) in a large kindred due to a silent exonic GLDC splice mutation. 2005 Apr 26 2
36 15864413 A single nucleotide substitution that abolishes the initiator methionine codon of the GLDC gene is prevalent among patients with glycine encephalopathy in Jerusalem. 2005 2
37 12126939 Novel mutations in the P-protein (glycine decarboxylase) gene in patients with glycine encephalopathy (non-ketotic hyperglycinemia). 2002 Jul 3
38 10806385 Interaction between the lipoamide-containing H-protein and the lipoamide dehydrogenase (L-protein) of the glycine decarboxylase multienzyme system. 1. Biochemical studies. 2000 May 1
39 10571879 Glycine and serine catabolism in non-photosynthetic higher plant cells: their role in C1 metabolism. 1999 Oct 2
40 7625831 Activation of glycine decarboxylase in pea leaf mitochondria by ATP. 1995 Jul 10 1
41 20301531 Nonketotic Hyperglycinemia 1993 1
42 3395333 The impaired expression of glycine decarboxylase in patients with hyperglycinemias. 1988 Jul 15 1
43 7153213 The mitochondrial glycine cleavage system: inactivation of glycine decarboxylase as a side reaction of the glycine decarboxylation in the presence of aminomethyl carrier protein. 1982 Nov 2
44 4362331 The metabolism of nitrilotriacetate by a pseudomonad. 1973 Dec 1