Glucose

insulin receptor substrate 1 ; Rattus norvegicus







65 Article(s)
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1 33233028 Berberine promotes peri-implant osteogenesis in diabetic rats by ROS-mediated IRS-1 pathway. 2021 Jan 1
2 33402476 Relationship Between Insulin-Receptor Substrate 1 and Langerhans' Islet in a Rat Model of Type 2 Diabetes Mellitus. 2021 Jan-Feb 1
3 33708999 Hyperinsulinemia Induced Altered Insulin Signaling Pathway in Muscle of High Fat- and Carbohydrate-Fed Rats: Effect of Exercise. 2021 1
4 34659435 Electroacupuncture at Bilateral ST36 Acupoints: Inducing the Hypoglycemic Effect through Enhancing Insulin Signal Proteins in a Streptozotocin-Induced Rat Model during Isoflurane Anesthesia. 2021 1
5 34734480 Exercise ameliorates insulin resistance and improves ASK1-mediated insulin signalling in obese rats. 2021 Dec 1
6 30596894 The Effects of Aging on Rho-Kinase and Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Rats. 2020 Feb 14 1
7 32032622 Physical exercise increases ROCK activity in the skeletal muscle of middle-aged rats. 2020 Mar 2
8 31089370 Study of the Antidiabetic Activity of Punica granatum L. Fruits Aqueous Extract on the Alloxan-Diabetic Wistar Rats. 2019 Winter 1
9 31629802 Rho-kinase activity is upregulated in the skeletal muscle of aged exercised rats. 2019 Dec 2
10 29219181 Exercise increases Rho-kinase activity and insulin signaling in skeletal muscle. 2018 Jun 2
11 30285704 A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats. 2018 Oct 1 1
12 28533752 Protocatechuic Acid, a Phenolic from Sansevieria roxburghiana Leaves, Suppresses Diabetic Cardiomyopathy via Stimulating Glucose Metabolism, Ameliorating Oxidative Stress, and Inhibiting Inflammation. 2017 1
13 26919700 MiR-126 Suppresses the Glucose-Stimulated Proliferation via IRS-2 in INS-1 β Cells. 2016 3
14 25268311 JNK and IKKβ phosphorylation is reduced by glucocorticoids in adipose tissue from insulin-resistant rats. 2015 Jan 1
15 25354240 Preserved Na/HCO3 cotransporter sensitivity to insulin may promote hypertension in metabolic syndrome. 2015 Mar 1
16 25779204 Carbamylated low-density lipoprotein attenuates glucose uptake via a nitric oxide-mediated pathway in rat L6 skeletal muscle cells. 2015 Jul 1
17 25802191 Anti-diabetic efficacy of KICG1338, a novel glycogen synthase kinase-3β inhibitor, and its molecular characterization in animal models of type 2 diabetes and insulin resistance. 2015 Jul 5 1
18 24462915 Molecular mechanisms underlying the effects of cyclosporin A and sirolimus on glucose and lipid metabolism in liver, skeletal muscle and adipose tissue in an in vivo rat model. 2014 Mar 15 1
19 24527778 PPARβ activation restores the high glucose-induced impairment of insulin signalling in endothelial cells. 2014 Jun 1
20 24845581 Effective glycaemic control critically determines insulin cardioprotection against ischaemia/reperfusion injury in anaesthetized dogs. 2014 Jul 15 1
21 25122003 Urocortin 3 activates AMPK and AKT pathways and enhances glucose disposal in rat skeletal muscle. 2014 Nov 1
22 23702602 The association of adipose-derived dimethylarginine dimethylaminohydrolase-2 with insulin sensitivity in experimental type 2 diabetes mellitus. 2013 Aug 1
23 24312573 Meta-modeling of methylprednisolone effects on glucose regulation in rats. 2013 1
24 22187297 Acute insulin resistance following surgical trauma in rats. 2012 Jun 1
25 21228767 Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity. 2011 Apr 2
26 21301931 Sex steroids influence glucose oxidation through modulation of insulin receptor expression and IRS-1 serine phosphorylation in target tissues of adult male rat. 2011 Jun 1
27 21716329 Angiotensin II shifts insulin signaling into vascular remodeling from glucose metabolism in vascular smooth muscle cells. 2011 Oct 1
28 19171190 Calcium-calmodulin-dependent kinase II (CaMKII) mediates insulin-stimulated proliferation and glucose uptake. 2009 May 2
29 19481554 Regulation of glucose-dependent insulin secretion by insulin: possible role of AMP-activated protein kinase. 2009 Jul 17 4
30 19699714 The ginsenoside Rg3 has a stimulatory effect on insulin signaling in L6 myotubes. 2009 Nov 6 1
31 17570255 Short-term in vitro inhibition of glycogen synthase kinase 3 potentiates insulin signaling in type I skeletal muscle of Zucker Diabetic Fatty rats. 2007 Jul 1
32 18000310 Low expression of insulin signaling molecules impairs glucose uptake in adipocytes after early overnutrition. 2007 Dec 1
33 15386812 Mediation of beta-endorphin in exercise-induced improvement in insulin resistance in obese Zucker rats. 2005 Mar-Apr 1
34 15591151 Western diet modulates insulin signaling, c-Jun N-terminal kinase activity, and insulin receptor substrate-1ser307 phosphorylation in a tissue-specific fashion. 2005 Mar 1
35 15845625 Insulin receptor substrates-1 and -2 are both depleted but via different mechanisms after down-regulation of glucose transport in rat adipocytes. 2005 Jul 2
36 15889998 Hyperglycemia potentiates H(2)O(2) production in adipocytes and enhances insulin signal transduction: potential role for oxidative inhibition of thiol-sensitive protein-tyrosine phosphatases. 2005 May-Jun 1
37 15921682 ERK1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells. 2005 Aug 15 1
38 15936776 Oxidative stress--mediated alterations in glucose dynamics in a genetic animal model of type II diabetes. 2005 Sep 30 2
39 16150913 Both saturated and n-6 polyunsaturated fat diets reduce phosphorylation of insulin receptor substrate-1 and protein kinase B in muscle during the initial stages of in vivo insulin stimulation. 2005 Dec 1
40 14764603 Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner. 2004 Apr 23 1
41 15004002 Enhanced insulin action on glucose transport and insulin signaling in 7-day unweighted rat soleus muscle. 2004 Jul 2
42 15068957 Interactions of exercise training and alpha-lipoic acid on insulin signaling in skeletal muscle of obese Zucker rats. 2004 Sep 1
43 15072564 Restoration of insulin secretion in pancreatic islets of protein-deficient rats by reduced expression of insulin receptor substrate (IRS)-1 and IRS-2. 2004 Apr 3
44 15240096 Reduction of insulin-stimulated glucose uptake by peroxynitrite is concurrent with tyrosine nitration of insulin receptor substrate-1. 2004 Jul 30 1
45 15326564 Alpha-lipoic acid mitigates insulin resistance in Goto-Kakizaki rats. 2004 Aug 2
46 15473137 Protein kinase C (PKC) beta modulates serine phosphorylation of insulin receptor substrate-1 (IRS-1)--effect of overexpression of PKCbeta on insulin signal transduction. 2004 May 1
47 12534369 High glucose and insulin in combination cause insulin receptor substrate-1 and -2 depletion and protein kinase B desensitisation in primary cultured rat adipocytes: possible implications for insulin resistance in type 2 diabetes. 2003 Jan 6
48 11842069 Clenbuterol prevents epinephrine from antagonizing insulin-stimulated muscle glucose uptake. 2002 Mar 1
49 11888850 Dexamethasone impairs insulin signalling and glucose transport by depletion of insulin receptor substrate-1, phosphatidylinositol 3-kinase and protein kinase B in primary cultured rat adipocytes. 2002 Mar 1
50 11916914 Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation. 2002 Apr 1