Lovastatin

ras homolog family member A ; Homo sapiens







21 Article(s)
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1 35168393 Lovastatin Inhibits RhoA to Suppress Canonical Wnt/β-Catenin Signaling and Alternative Wnt-YAP/TAZ Signaling in Colon Cancer. 2022 Jan-Dec 2
2 26409448 The role of RhoA in vulvar squamous cell carcinoma: a carcinogenesis, progression, and target therapy marker. 2016 Mar 3
3 22396212 Prenylation of Rho G-proteins: a novel mechanism regulating gene expression and protein stability in human trabecular meshwork cells. 2012 Aug 3
4 21907187 Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway. 2011 Dec 1 1
5 20455727 HMG-CoA reductase inhibitor lovastatin causes reversible cytoskeleton perturbation by RhoA signalling suppression in peritoneal cell line Met5A. 2010 May 7
6 20562912 Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: potential regulation by targeting rho proteins. 2010 Aug 19 2
7 19151402 Increased RhoA and RhoB protein accumulation in cultured human trabecular meshwork cells by lovastatin. 2009 Jun 6
8 19571581 Leptin stimulated C-reactive protein production by human coronary artery endothelial cells. 2009 1
9 17920041 Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors. 2008 Jan 15 2
10 18199714 Statin induces apoptosis and cell growth arrest in prostate cancer cells. 2008 Jan 1
11 19038009 Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer. 2008 Dec 1
12 16316623 Lovastatin-induced RhoA modulation and its effect on senescence in prostate cancer cells. 2006 Jan 20 3
13 16751413 Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease. 2006 Jun 15 3
14 16172195 Lovastatin suppresses invasiveness of anaplastic thyroid cancer cells by inhibiting Rho geranylgeranylation and RhoA/ROCK signaling. 2005 Sep 2
15 19956523 Characterization of RhoA-mediated chemoresistance in gastric cancer cells. 2005 Aug 1
16 12933658 Lovastatin induces apoptosis of anaplastic thyroid cancer cells via inhibition of protein geranylgeranylation and de novo protein synthesis. 2003 Sep 2
17 14572607 Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha. 2003 Nov 1 2
18 12082550 Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas. 2002 Jul-Aug 2
19 10559211 Integrin-dependent leukocyte adhesion involves geranylgeranylated protein(s). 1999 Nov 19 1
20 9398081 Lovastatin induces apoptosis by inhibiting mitotic and post-mitotic events in cultured mesangial cells. 1997 Oct 30 1
21 8039707 Utilization of multiple polyadenylation signals in the human RHOA protooncogene. 1994 Jul 8 1