lactacystin

tumor protein p53 ; Homo sapiens







16 Article(s)
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Pub. Year
#Total Relationships
1 19337030 An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity. 2009 Jul 4
2 16051302 Accumulation of p53 in response to adenovirus early region 1A sensitizes human cells to tumor necrosis factor alpha-induced apoptosis. 2005 Sep 30 1
3 16127151 Cleavage of p53-vimentin complex enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of rheumatoid arthritis synovial fibroblasts. 2005 Sep 3
4 15147952 Transcriptional repression of E2F gene by proteasome inhibitors in human osteosarcoma cells. 2004 Jun 11 1
5 11158615 Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1. 2001 Jan 30 1
6 11375905 Deoxycholic acid suppresses p53 by stimulating proteasome-mediated p53 protein degradation. 2001 Jun 3
7 11397792 Human mdm2 mediates multiple mono-ubiquitination of p53 by a mechanism requiring enzyme isomerization. 2001 Aug 17 3
8 10845931 p53 stabilization and functional impairment in the absence of genetic mutation or the alteration of the p14(ARF)-MDM2 loop in ex vivo and cultured adult T-cell leukemia/lymphoma cells. 2000 Jun 15 1
9 10891461 Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes. 2000 Jul 1 2
10 11073163 Proteasome inhibitors induced caspase-dependent apoptosis and accumulation of p21WAF1/Cip1 in human immature leukemic cells. 2000 Oct 1
11 9989601 Proteasome inhibitors induce mitochondria-independent apoptosis in human glioma cells. 1999 Jan 25 2
12 10082548 Requirement of ATM in phosphorylation of the human p53 protein at serine 15 following DNA double-strand breaks. 1999 Apr 4
13 10628338 Induction of G1 arrest and selective growth inhibition by lactacystin in human umbilical vein endothelial cells. 1999 Sep-Oct 2
14 9438391 mdm2 and bax, downstream mediators of the p53 response, are degraded by the ubiquitin-proteasome pathway. 1998 Jan 1
15 9266962 Transcriptional squelching by ectopic expression of E2F-1 and p53 is alleviated by proteasome inhibitors MG-132 and lactacystin. 1997 Aug 14 2
16 8878553 Proteasome-dependent regulation of p21WAF1/CIP1 expression. 1996 Oct 14 1