Chloroquine

tumor protein p53 ; Homo sapiens







28 Article(s)
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1 35163553 Different Cell Responses to Hinokitiol Treatment Result in Senescence or Apoptosis in Human Osteosarcoma Cell Lines. 2022 Jan 31 1
2 32640976 WRN inhibits oxidative stress-induced apoptosis of human lensepithelial cells through ATM/p53 signaling pathway and its expression is downregulated by DNA methylation. 2020 Jul 8 1
3 30483736 Attenuation of autophagy flux by 6-shogaol sensitizes human liver cancer cells to TRAIL-induced apoptosis via p53 and ROS. 2019 Feb 1
4 29435010 Chloroquine potentiates the anticancer effect of sunitinib on renal cell carcinoma by inhibiting autophagy and inducing apoptosis. 2018 Mar 1
5 29665004 Thiostrepton degrades mutant p53 by eliciting an autophagic response in SW480 cells. 2018 Oct 2
6 28076793 Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis. 2017 Jan 10 2
7 28131902 CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk. 2017 Mar 7
8 27109480 Anti-inflammatory activity of chloroquine and amodiaquine through p21-mediated suppression of T cell proliferation and Th1 cell differentiation. 2016 May 27 1
9 27599722 Reactivation of mutant p53 by capsaicin, the major constituent of peppers. 2016 Sep 6 1
10 25681668 The synergistic effect of combination temozolomide and chloroquine treatment is dependent on autophagy formation and p53 status in glioma cells. 2015 May 1 7
11 25734693 The utility of chloroquine in cancer therapy. 2015 May 2
12 24727941 Chloroquine potentiates the anti-cancer effect of lidamycin on non-small cell lung cancer cells in vitro. 2014 May 1
13 24804820 The cytoprotective role of gemcitabine-induced autophagy associated with apoptosis inhibition in triple-negative MDA-MB-231 breast cancer cells. 2014 Jul 1
14 25551567 Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine. 2014 1
15 23238993 Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells from apoptosis. 2013 Mar 1
16 24083726 Autophagy inhibition sensitizes cisplatin cytotoxicity in human gastric cancer cell line SGC7901. 2013 1
17 21964832 Effect of berberine on p53 expression by TPA in breast cancer cells. 2012 Jan 1
18 22142888 Akt and p53 are potential mediators of reduced mammary tumor growth by cloroquine and the mTOR inhibitor RAD001. 2012 Feb 15 2
19 22716215 Chloroquine enhances the chemotherapeutic activity of 5-fluorouracil in a colon cancer cell line via cell cycle alteration. 2012 Jul 1
20 20175992 Selective binding of tumor suppressor p53 protein to topologically constrained DNA: Modulation by intercalative drugs. 2010 Mar 19 2
21 20308316 Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells. 2010 Apr 4
22 20406898 Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent. 2010 May 3
23 19597352 A role for p53 in the regulation of extracellular matrix metalloproteinase inducer in human cancer cells. 2009 Sep 1
24 18097482 Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis. 2008 Jan 1
25 17235397 Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. 2007 Feb 1
26 18089834 Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis. 2007 Dec 15 4
27 16426903 Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity. 2006 Apr 8 1
28 12082016 High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter. 2002 Jun 1