NVP-CGM097

tumor protein p53 ; Homo sapiens







6 Article(s)
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1 34140638 Pharmacokinetic-pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies. 2021 Aug 2
2 27871087 The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1. 2018 2
3 30217415 In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor. 2018 Nov 1 1
4 27507190 Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma. 2016 Jun 7 1
5 25965177 A distinct p53 target gene set predicts for response to the selective p53-HDM2 inhibitor NVP-CGM097. 2015 May 12 2
6 26206331 Inhibition of Wild-Type p53-Expressing AML by the Novel Small Molecule HDM2 Inhibitor CGM097. 2015 Oct 4