nutlin

tumor protein p53 ; Homo sapiens







14 Article(s)
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Pub. Year
#Total Relationships
1 33216890 Transient expansion of TP53 mutated clones in polycythemia vera patients treated with idasanutlin. 2020 Nov 24 1
2 31607444 P53-induced reduction of lipid peroxidation supports brain microvascular endothelium integrity. 2019 Sep 1
3 29932882 p53 inhibition by MDM2 in human pterygium. 2018 Oct 1
4 26883108 Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3. 2016 Mar 22 1
5 24366007 Nutlin-3 induces HO-1 expression by activating JNK in a transcription-independent manner of p53. 2014 Mar 2
6 24885082 Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia. 2014 May 21 1
7 23856246 The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology. 2013 Jul 15 1
8 22578852 Comparison of the antitumor effects of an MDM2 inhibitor, nutlin-3, in feline lymphoma cell lines with or without p53 mutation. 2012 Jun 30 2
9 20871630 p21 does not protect cancer cells from apoptosis induced by nongenotoxic p53 activation. 2011 Jan 20 1
10 20371712 Nutlin-3a induces cytoskeletal rearrangement and inhibits the migration and invasion capacity of p53 wild-type cancer cells. 2010 Apr 2
11 20424123 Transcriptional repression of SKP2 is impaired in MYCN-amplified neuroblastoma. 2010 May 1 1
12 19190243 Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism. 2009 Apr 30 2
13 19411846 The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells. 2009 Jun 1 2
14 19509161 Restoration of p53 pathway by nutlin-3 induces cell cycle arrest and apoptosis in human rhabdomyosarcoma cells. 2009 Jun 15 1