| 1 |
33773191 | Bibenzyl analogue DS-1 inhibits MDM2-mediated p53 degradation and sensitizes apoptosis in lung cancer cells. | 2021 May |
1 |
| 2 |
34478701 | Hidden electrostatic energy contributions define dynamic allosteric communications within p53 during molecular recognition. | 2021 Oct 19 |
1 |
| 3 |
31547774 | Sulfonamide phenylalanine (SPA) series of analogues as an antibacterial, antifungal, anticancer agents along with p53 tumor suppressor-DNA complex inhibitor - part 1. | 2020 Sep |
1 |
| 4 |
32337406 | Computational Investigation on the p53-MDM2 Interaction Using the Potential of Mean Force Study. | 2020 Apr 21 |
1 |
| 5 |
32457871 | Hybrid Molecular Dynamics for Elucidating Cooperativity Between Halogen Bond and Water Molecules During the Interaction of p53-Y220C and the PhiKan5196 Complex. | 2020 |
1 |
| 6 |
32583165 | 1H, 13C and 15N backbone resonance assignment of BRCA1 fragment 219-504. | 2020 Oct |
1 |
| 7 |
32649952 | Pentamidine inhibit S100A4 - p53 interaction and decreases cell proliferation activity. | 2020 Sep 30 |
1 |
| 8 |
30873235 | Design of indole- and MCR-based macrocycles as p53-MDM2 antagonists. | 2019 |
1 |
| 9 |
29260852 | Targeting the Prion-like Aggregation of Mutant p53 to Combat Cancer. | 2018 Jan 16 |
1 |
| 10 |
29988358 | Benzimidazoisoquinoline derivatives inhibit glioblastoma cell proliferation through down-regulating Raf/MEK/ERK and PI3K/AKT pathways. | 2018 |
1 |
| 11 |
28696098 | Enhanced Binding Affinity via Destabilization of the Unbound State: A Millisecond Hydrogen-Deuterium Exchange Study of the Interaction between p53 and a Pleckstrin Homology Domain. | 2017 Aug 15 |
1 |
| 12 |
26585176 | An anthraquinone derivative from Luffa acutangula induces apoptosis in human lung cancer cell line NCI-H460 through p53-dependent pathway. | 2016 |
1 |
| 13 |
26812210 | Monitoring Ligand-Induced Protein Ordering in Drug Discovery. | 2016 Mar 27 |
1 |
| 14 |
27600721 | Aggregation tendencies in the p53 family are modulated by backbone hydrogen bonds. | 2016 Sep 7 |
2 |
| 15 |
27792778 | Hydrogen Bond Dynamic Propensity Studies for Protein Binding and Drug Design. | 2016 |
2 |
| 16 |
26098630 | A Novel Protein Interaction between Nucleotide Binding Domain of Hsp70 and p53 Motif. | 2015 |
1 |
| 17 |
26579714 | Investigating DNA Binding and Conformational Variation in Temperature Sensitive p53 Cancer Mutants Using QM-MM Simulations. | 2015 |
2 |
| 18 |
24601644 | Novel inhibitors of the MDM2-p53 interaction featuring hydrogen bond acceptors as carboxylic acid isosteres. | 2014 Apr 10 |
1 |
| 19 |
25056872 | Electrochemical detection of DNA binding by tumor suppressor p53 protein using osmium-labeled oligonucleotide probes and catalytic hydrogen evolution at the mercury electrode. | 2014 Sep |
1 |
| 20 |
23030661 | p53-Pathway activity and apoptosis in hydrogen sulfide-exposed stem cells separated from human gingival epithelium. | 2013 Jun |
1 |
| 21 |
23863845 | Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. | 2013 Oct |
1 |
| 22 |
24253321 | QM-MM simulations on p53-DNA complex: a study of hot spot and rescue mutants. | 2013 Dec |
1 |
| 23 |
21898049 | 1H, 13C, and 15N backbone and side-chain chemical shift assignments for the 31 kDa human galectin-7 (p53-induced gene 1) homodimer, a pro-apoptotic lectin. | 2012 Oct |
1 |
| 24 |
23046248 | Discovery, synthesis, and biological evaluation of orally active pyrrolidone derivatives as novel inhibitors of p53-MDM2 protein-protein interaction. | 2012 Nov 26 |
1 |
| 25 |
21460846 | The client protein p53 adopts a molten globule-like state in the presence of Hsp90. | 2011 May |
1 |
| 26 |
21880715 | Structure of human SMYD2 protein reveals the basis of p53 tumor suppressor methylation. | 2011 Nov 4 |
1 |
| 27 |
19856322 | Preferred drifting along the DNA major groove and cooperative anchoring of the p53 core domain: mechanisms and scenarios. | 2010 Mar-Apr |
1 |
| 28 |
20403587 | The effect of R249S carcinogenic and H168R-R249S suppressor mutations on p53-DNA interaction, a multi scale computational study. | 2010 May |
1 |
| 29 |
20821791 | High specificity in protein recognition by hydrogen-bond-surrogate α-helices: selective inhibition of the p53/MDM2 complex. | 2010 Oct 18 |
1 |
| 30 |
19408261 | Thermodynamic and computational studies on the binding of p53-derived peptides and peptidomimetic inhibitors to HDM2. | 2009 May 25 |
1 |
| 31 |
16461914 | Core domain interactions in full-length p53 in solution. | 2006 Feb 14 |
1 |
| 32 |
14706517 | Alteration of the ATM gene occurs in gastric cancer cell lines and primary tumors associated with cellular response to DNA damage. | 2004 Jan 10 |
1 |
| 33 |
18969416 | Fluorescence detection of cytosine/guanine transversion based on a hydrogen bond forming ligand. | 2004 May 10 |
1 |
| 34 |
11917017 | Factors governing loss and rescue of DNA binding upon single and double mutations in the p53 core domain. | 2002 Apr 1 |
1 |
| 35 |
12370832 | Mdm-2 binding and TAF(II)31 recruitment is regulated by hydrogen bond disruption between the p53 residues Thr18 and Asp21. | 2002 Oct 10 |
6 |
| 36 |
11559355 | Hydrogen exchange of the tetramerization domain of the human tumour suppressor p53 probed by denaturants and temperature. | 2001 Sep |
2 |
| 37 |
10909873 | Sequence-specific 1H, 15N, and 13C assignment of the N-terminal domain of the human oncoprotein MDM2 that binds to p53. | 2000 May |
1 |
| 38 |
11101222 | Assignment of 1H(N), 15N, 13C(alpha), 13CO and 13C(beta) resonances in a 67 kDa p53 dimer using 4D-TROSY NMR spectroscopy. | 2000 Oct |
1 |
| 39 |
9499782 | Sebaceous carcinoma. Tumor progression through mutational inactivation of p53. | 1998 Mar |
1 |
| 40 |
8615376 | Suppression of cellular proliferation using p53 DNA recognition site-related oligonucleotides. | 1996 Feb |
1 |
| 41 |
7663341 | Backbone dynamics of the oligomerization domain of p53 determined from 15N NMR relaxation measurements. | 1995 May |
1 |