5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one

tumor protein p53 ; Homo sapiens







10 Article(s)
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Pub. Year
#Total Relationships
1 34188177 Novel CDK9 inhibitor oroxylin A promotes wild-type P53 stability and prevents hepatocellular carcinoma progression by disrupting both MDM2 and SIRT1 signaling. 2022 Apr 1
2 34149863 Molecular Targets and Mechanisms of Scutellariae radix-Coptidis rhizoma Drug Pair for the Treatment of Ulcerative Colitis Based on Network Pharmacology and Molecular Docking. 2021 1
3 31884961 Correction to: Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells. 2019 Dec 30 2
4 26958937 Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wild-type p53. 2016 Mar 29 5
5 25902914 Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells. 2015 Apr 23 12
6 23470866 Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest. 2013 May 23 1
7 23612020 Two p53-related metabolic regulators, TIGAR and SCO2, contribute to oroxylin A-mediated glucose metabolism in human hepatoma HepG2 cells. 2013 Jul 10
8 22607196 Oroxylin A improves the sensitivity of HT-29 human colon cancer cells to 5-FU through modulation of the COX-2 signaling pathway. 2012 Aug 1
9 19585117 Synergistic effect of 5-fluorouracil and the flavanoid oroxylin A on HepG2 human hepatocellular carcinoma and on H22 transplanted mice. 2010 Feb 1
10 19626645 Involvement of p53 in oroxylin A-induced apoptosis in cancer cells. 2009 Dec 12