7-ethyl-7-hydroxy-10H-1,3-Dioxolo(4,5-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8,11(7H,12H)-dione

tumor protein p53 ; Homo sapiens







4 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34377229 Kras mutation subtypes distinctly affect colorectal cancer cell sensitivity to FL118, a novel inhibitor of survivin, Mcl-1, XIAP, cIAP2 and MdmX. 2021 2
2 24959385 Anticancer drug FL118 is more than a survivin inhibitor: where is the Achilles' heel of cancer? 2014 2
3 25512388 FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX. 2014 Dec 15 9
4 23029106 A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity. 2012 3