| 1 |
32825184 | HP1γ Sensitizes Cervical Cancer Cells to Cisplatin through the Suppression of UBE2L3. | 2020 Aug 19 |
2 |
| 2 |
29973205 | Inhibition of CRM1 activity sensitizes endometrial and ovarian cell lines to TRAIL-induced cell death. | 2018 Jul 4 |
3 |
| 3 |
26516353 | Nucleocytoplasmic Translocation of UBXN2A Is Required for Apoptosis during DNA Damage Stresses in Colon Cancer Cells. | 2015 |
3 |
| 4 |
22412944 | Chemotherapeutic sensitization of leptomycin B resistant lung cancer cells by pretreatment with doxorubicin. | 2012 |
3 |
| 5 |
22517433 | An evaluation of small-molecule p53 activators as chemoprotectants ameliorating adverse effects of anticancer drugs in normal cells. | 2012 May 1 |
2 |
| 6 |
20803015 | p53-Dependent anticancer effects of leptomycin B on lung adenocarcinoma. | 2011 Jun |
4 |
| 7 |
19751709 | Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells. | 2009 Dec 10 |
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| 8 |
18784437 | Combined effects of p53 gene therapy and leptomycin B in human esophageal squamous cell carcinoma. | 2008 |
2 |
| 9 |
17245118 | CYFIP2, a direct p53 target, is leptomycin-B sensitive. | 2007 Jan 1 |
1 |
| 10 |
17290384 | Selective induction of apoptosis by leptomycin B in keratinocytes expressing HPV oncogenes. | 2007 Jun 1 |
2 |
| 11 |
17409429 | Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells. | 2007 Apr 1 |
2 |
| 12 |
16467109 | Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53. | 2006 Feb 1 |
1 |
| 13 |
15625077 | HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage. | 2005 Mar |
1 |
| 14 |
15994771 | Involvement of nuclear export in human papillomavirus type 18 E6-mediated ubiquitination and degradation of p53. | 2005 Jul |
1 |
| 15 |
14757188 | Phosphorylation and nuclear accumulation are distinct events contributing to the activation of p53. | 2004 Feb 26 |
1 |
| 16 |
15193998 | Leptomycin B-induced apoptosis is mediated through caspase activation and down-regulation of Mcl-1 and XIAP expression, but not through the generation of ROS in U937 leukemia cells. | 2004 Jul 15 |
1 |
| 17 |
12539224 | Leptomycin B stabilizes and activates p53 in primary prostatic epithelial cells and induces apoptosis in the LNCaP cell line. | 2003 Mar 1 |
4 |
| 18 |
12592381 | Nuclear export inhibitor leptomycin B induces the appearance of novel forms of human Mdm2 protein. | 2003 Feb 24 |
4 |
| 19 |
12653667 | Protecting p53 from degradation. | 2003 Apr |
1 |
| 20 |
12704785 | Central and carboxy-terminal regions of human p53 protein are essential for interaction and complex formation with PARP-1. | 2003 May 15 |
2 |
| 21 |
12807744 | Hypoxia induces p53 through a pathway distinct from most DNA-damaging and stress-inducing agents. | 2003 Jul |
2 |
| 22 |
12958168 | Nuclear and cytoplasmic degradation of endogenous p53 and HDM2 occurs during down-regulation of the p53 response after multiple types of DNA damage. | 2003 Sep |
1 |
| 23 |
14662026 | Leptomycin B enhances CDDP-sensitivity via nuclear accumulation of p53 protein in HPV-positive cells. | 2003 Dec |
4 |
| 24 |
11375905 | Deoxycholic acid suppresses p53 by stimulating proteasome-mediated p53 protein degradation. | 2001 Jun |
3 |
| 25 |
10645001 | Nuclear exclusion of p53 in a subset of tumors requires MDM2 function. | 2000 Jan 13 |
1 |
| 26 |
10900010 | Activation of p53 in cervical carcinoma cells by small molecules. | 2000 Jul 18 |
1 |
| 27 |
11025661 | p53 is associated with cellular microtubules and is transported to the nucleus by dynein. | 2000 Oct |
1 |
| 28 |
11127820 | MDM2-dependent ubiquitination of nuclear and cytoplasmic P53. | 2000 Nov 30 |
2 |
| 29 |
10075936 | A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. | 1999 Mar 15 |
3 |
| 30 |
10222137 | An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs. | 1999 May 1 |
3 |
| 31 |
10602494 | Effects on normal fibroblasts and neuroblastoma cells of the activation of the p53 response by the nuclear export inhibitor leptomycin B. | 1999 Dec 2 |
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| 32 |
9819415 | Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6. | 1998 Dec |
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