thymoquinone

tumor protein p53 ; Homo sapiens







21 Article(s)
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1 33747489 Therapeutic perspective of thymoquinone: A mechanistic treatise. 2021 Mar 1
2 34959424 Phyto-Phospholipid Conjugated Scorpion Venom Nanovesicles as Promising Carrier That Improves Efficacy of Thymoquinone against Adenocarcinoma Human Alveolar Basal Epithelial Cells. 2021 Dec 13 1
3 32272181 Thymoquinone synergizes with arsenic and interferon alpha to target human T-cell leukemia/lymphoma. 2020 Jun 15 1
4 33041795 Thymoquinone Selectively Induces Hepatocellular Carcinoma Cell Apoptosis in Synergism With Clinical Therapeutics and Dependence of p53 Status. 2020 3
5 30521787 Cabazitaxel and thymoquinone co-loaded lipospheres as a synergistic combination for breast cancer. 2019 Nov 1
6 31433961 Thymoquinone induces apoptosis of human epidermoid carcinoma A431 cells through ROS-mediated suppression of STAT3. 2019 Oct 1 1
7 28901264 Inhibition of Proliferation and Induction of Apoptosis by Thymoquinone via Modulation of TGF Family, p53, p21 and Bcl-2α in Leukemic Cells. 2018 1
8 29656006 Par-4-dependent p53 up-regulation plays a critical role in thymoquinone-induced cellular senescence in human malignant glioma cells. 2018 Jul 10 2
9 26848703 Thymoquinone from Nigella sativa Seeds Promotes the Antitumor Activity of Noncytotoxic Doses of Topotecan in Human Colorectal Cancer Cells in Vitro. 2016 Mar 1
10 27141285 Effect of Thymoquinone on P53 Gene Expression and Consequence Apoptosis in Breast Cancer Cell Line. 2016 2
11 25975351 Differential Cellular Effects of Plk1 Inhibitors Targeting the ATP-binding Domain or Polo-box Domain. 2015 Dec 1
12 25241984 Apoptotic activities of thymoquinone, an active ingredient of black seed (Nigella sativa), in cervical cancer cell lines. 2014 Oct 31 2
13 22960073 NADPH quinone oxidoreductase 1 mediates breast cancer cell resistance to thymoquinone-induced apoptosis. 2012 Sep 28 1
14 20807569 Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis. 2011 Jan 1
15 20026309 Induction of apoptosis by thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator UHRF1. 2010 May 1 2
16 22993551 Thymoquinone hydrazone derivatives cause cell cycle arrest in p53-competent colorectal cancer cells. 2010 Mar 1
17 18632613 Thymoquinone triggers inactivation of the stress response pathway sensor CHEK1 and contributes to apoptosis in colorectal cancer cells. 2008 Jul 15 4
18 17218778 Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells. 2007 Feb 4
19 16314136 Thymoquinone: a promising anti-cancer drug from natural sources. 2006 2
20 15906362 Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells. 2005 Nov 10 2
21 15375533 Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism. 2004 Oct 1